EMD-18659

Single-particle
2.9 Å
EMD-18659
3D View Gallery
Deposition: 16/10/2023
Map released: 03/04/2024
Last modified: 03/04/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-18659

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8quc summary report (pdf.gz) Map-8quc FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM Structure of Human Kv3.1 in Complex with Modulator AUT1

EMD-18659

Single-particle
2.9 Å
EMD-18659
3D View Gallery
Deposition: 16/10/2023
Map released: 03/04/2024
Last modified: 03/04/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Homotetramer of Human Kv3.1a with modulator AUT1
Fitted models: 8quc

Deposition Authors: Chi G , Mckinley G, Marsden B, Pike ACW, Ye M, Brooke LM, Bakshi S, Pilati N, Marasco A , Gunthorpe M, Alvaro G, Large C, Lakshminaraya B, Williams E, Sauer DB
The binding and mechanism of a positive allosteric modulator of Kv3 channels.
Liang Q , Chi G , Cirqueira L , Zhi L, Marasco A , Pilati N, Gunthorpe MJ , Alvaro G, Large CH , Sauer DB , Treptow W , Covarrubias M
(2024) Nat Commun , 15 , 2533 - 2533
PUBMED: 38514618
DOI: doi:10.1038/s41467-024-46813-8
ISSN: 2041-1723
Grant Support: