EMD-18230

Single-particle
3.71 Å
EMD-18230
3D View Gallery
Deposition: 16/08/2023
Map released: 21/02/2024
Last modified: 09/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-18230

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8q7r summary report (pdf.gz) Map-8q7r FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Ubiquitin ligation to substrate by a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-FEM1C with trapped UBE2R2~donor UB-Sil1 peptide

EMD-18230

Single-particle
3.71 Å
EMD-18230
3D View Gallery
Deposition: 16/08/2023
Map released: 21/02/2024
Last modified: 09/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Ubiquitin ligation to substrate by a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-FEM1C with trapped UBE2R2~donor UB-Sil1 peptide
Fitted models: 8q7r

Deposition Authors: Liwocha J , Prabu JR , Kleiger G, Schulman BA
Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting.
Li J , Purser N, Liwocha J , Scott DC, Byers HA, Steigenberger B, Hill S, Tripathi-Giesgen I , Hinkle T, Hansen FM, Prabu JR , Radhakrishnan SK, Kirkpatrick DS, Reichermeier KM, Schulman BA , Kleiger G
(2024) Mol Cell , 84 , 1304
PUBMED: 38382526
DOI: doi:10.1016/j.molcel.2024.01.022
ISSN: 1097-2765
ASTM: MOCEFL
Grant Support: