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EMD-18218
Structure of CUL9-RBX1 ubiquitin E3 ligase complex in unneddylated and neddylated conformation - focused dimeric core
EMD-18218
Single-particle3.5 Å
Deposition: 16/08/2023Map released: 17/04/2024
Last modified: 31/07/2024
Sample Organism:
Homo sapiens
Sample: Structure of CUL9-RBX1 ubiquitin E3 ligase complex in unneddylated and neddylated conformation - focused dimeric core
Deposition Authors: Hopf LVM
,
Horn-Ghetko D ,
Schulman BA
Sample: Structure of CUL9-RBX1 ubiquitin E3 ligase complex in unneddylated and neddylated conformation - focused dimeric core
Deposition Authors: Hopf LVM
,
Horn-Ghetko D ,
Schulman BA
Noncanonical assembly, neddylation and chimeric cullin-RING/RBR ubiquitylation by the 1.8 MDa CUL9 E3 ligase complex.
Horn-Ghetko D ,
Hopf LVM ,
Tripathi-Giesgen I ,
Du J ,
Kostrhon S,
Vu DT,
Beier V,
Steigenberger B,
Prabu JR ,
Stier L,
Bruss EM ,
Mann M ,
Xiong Y ,
Schulman BA
(2024) Nat Struct Mol Biol , 31 , 1083 - 1094
,
Hopf LVM ,
Tripathi-Giesgen I ,
Du J ,
Kostrhon S,
Vu DT,
Beier V,
Steigenberger B,
Prabu JR ,
Stier L,
Bruss EM ,
Mann M ,
Xiong Y ,
Schulman BA
(2024) Nat Struct Mol Biol , 31 , 1083 - 1094
Grant Support:
- European Research Council (ERC): 789016 (European Union)
- Max Planck Society: (Germany)