EMD-17748

Single-particle
2.26 Å
EMD-17748
3D View Gallery
Deposition: 27/06/2023
Map released: 15/01/2025
Last modified: 12/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-17748

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8pkn summary report (pdf.gz) Map-8pkn FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

CryoEM structure of catalytic domain of human HMG-CoA reductase with its inhibitor atorvastatin

EMD-17748

Single-particle
2.26 Å
EMD-17748
3D View Gallery
Deposition: 27/06/2023
Map released: 15/01/2025
Last modified: 12/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Catalytic part of hHMGCoA reductase
Fitted models: 8pkn

Deposition Authors: Manikandan K, Van Rooyen J
Cryo-EM structures of apo and atorvastatin-bound human 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
Karuppasamy M, van Rooyen J
(2025) Acta Crystallogr F Struct Biol Commun , 81 , 118 - 122
PUBMED: 39976191
DOI: doi:10.1107/S2053230X25001098
ISSN: 2053-230X
ASTM: ACSFEN
Grant Support: