EMD-17712

Single-particle
2.4 Å
EMD-17712
3D View Gallery
Deposition: 23/06/2023
Map released: 29/05/2024
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-17712
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8pjk summary report (pdf.gz) Map and 8pjk FULL report (pdf.gz)
EMICSS annotations (xml)

ST171-bound serotonin 5-HT1A receptor - Gi Protein Complex

EMD-17712

Single-particle
2.4 Å
EMD-17712
3D View Gallery
Deposition: 23/06/2023
Map released: 29/05/2024
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: ST171-bound Serotonin 5-HT1A receptor - Gi Protein Complex
Fitted models: 8pjk

Deposition Authors: Schneider J , Gmeiner P , Rasmussen T , Boettcher B
Discovery of a functionally selective serotonin receptor (5-HT 1A R) agonist for the treatment of pain.
Ullrich A , Schneider J , Braz JM , Neu E , Staffen N, Stanek M, Blahova J , Hove T , Albert T, Allikalt A , Lober S, Bhardwaj K , Rodriguez-Rosado S , Fink E, Rasmussen T , Hubner H , Inoue A , Shoichet BK , Basbaum AI , Bottcher B, Weikert D , Gmeiner P
(2025) Sci Adv , 11 , eadv9267 - eadv9267
PUBMED: 40531992
DOI: doi:10.1126/sciadv.adv9267
ISSN: 2375-2548
Grant Support: