Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-17699

Single-particle
3.2 Å
EMD-17699
3D View Gallery
Deposition: 22/06/2023
Map released: 14/08/2024
Last modified: 29/01/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-17699
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8pj4 summary report (pdf.gz) Map and 8pj4 FULL report (pdf.gz)
EMICSS annotations (xml)

Structure of human 48S translation initiation complex after eIF5 release (48S-4)

EMD-17699

Single-particle
3.2 Å
EMD-17699
3D View Gallery
Deposition: 22/06/2023
Map released: 14/08/2024
Last modified: 29/01/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human 48S initiation complex 40S-eIF1A-eIF2-eIF3-eIF5B-tRNA-Met-mRNA
Fitted models: 8pj4

Deposition Authors: Petrychenko V , Yi S-H, Liedtke D , Peng BZ, Rodnina MV, Fischer N
Structural basis for translational control by the human 48S initiation complex.
Petrychenko V , Yi SH, Liedtke D , Peng BZ, Rodnina MV, Fischer N
(2025) Nat Struct Mol Biol , 32 , 62 - 72
PUBMED: 39289545
DOI: doi:10.1038/s41594-024-01378-4
ISSN: 1545-9985