EMD-17518

Single-particle
2.0 Å
EMD-17518
3D View Gallery
Deposition: 30/05/2023
Map released: 20/03/2024
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-17518

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8p75 summary report (pdf.gz) Map-8p75 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of CAK in complex with inhibitor ICEC0880 (ring-down conformation)

EMD-17518

Single-particle
2.0 Å
EMD-17518
3D View Gallery
Deposition: 30/05/2023
Map released: 20/03/2024
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: CDK-activating kinase
Fitted models: 8p75

Deposition Authors: Cushing VI , Koh AF , Feng J, Jurgaityte K , Bahl AK, Ali S , Kotecha A , Greber BJ
High-resolution cryo-EM of the human CDK-activating kinase for structure-based drug design.
Cushing VI , Koh AF , Feng J, Jurgaityte K , Bondke A, Kroll SHB, Barbazanges M , Scheiper B, Bahl AK, Barrett AGM , Ali S , Kotecha A , Greber BJ
(2024) Nat Commun , 15 , 2265 - 2265
PUBMED: 38480681
DOI: doi:10.1038/s41467-024-46375-9
ISSN: 2041-1723