EMD-16891
Structure of the UBE1L activating enzyme bound to ISG15 and UBE2L6
EMD-16891
Single-particle3.5 Å
Deposition: 22/03/2023Map released: 13/12/2023
Last modified: 02/07/2025
Sample Organism:
Homo sapiens
Sample: Ternary complex consisting of UBE1L, UBE2L6, and full-length ISG15.
Fitted models: 8oif
Deposition Authors: Wallace I
,
Kheewoong B,
Prabu JR ,
Vollrath R,
von Gronau S,
Schulman BA ,
Swatek KN
Sample: Ternary complex consisting of UBE1L, UBE2L6, and full-length ISG15.
Fitted models: 8oif
Deposition Authors: Wallace I
,
Kheewoong B,
Prabu JR ,
Vollrath R,
von Gronau S,
Schulman BA ,
Swatek KN
Insights into the ISG15 transfer cascade by the UBE1L activating enzyme.
Wallace I ,
Baek K ,
Prabu JR ,
Vollrath R,
von Gronau S,
Schulman BA ,
Swatek KN
(2023) Nat Commun , 14 , 7970 - 7970
,
Baek K ,
Prabu JR ,
Vollrath R,
von Gronau S,
Schulman BA ,
Swatek KN
(2023) Nat Commun , 14 , 7970 - 7970
Grant Support:
- Medical Research Council (MRC, United Kingdom): MC_UU_00018/10 (United Kingdom)
- Royal Society: RGS_R2_222185 (United Kingdom)
- Max Planck Society: (Germany)
- European Research Council (ERC): (European Union)