EMD-16823

Single-particle
6.7 Å
EMD-16823
3D View Gallery
Deposition: 10/03/2023
Map released: 07/02/2024
Last modified: 01/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-16823

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of the murine IL-12 complete extracellular signaling complex (Class 2).

EMD-16823

Single-particle
6.7 Å
EMD-16823
3D View Gallery
Deposition: 10/03/2023
Map released: 07/02/2024
Last modified: 01/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus
Sample: Murine IL-12 in complex with Strep-II tagged mIL-12Rbeta1 and mIL-12Rbeta2.

Deposition Authors: Felix J , Bloch Y , Savvides SN
Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.
Bloch Y , Felix J , Merceron R, Provost M, Symakani RA , De Backer R , Lambert E, Mehdipour AR, Savvides SN
(2024) Nat Struct Mol Biol , 31 , 591 - 597
PUBMED: 38287195
DOI: doi:10.1038/s41594-023-01190-6
ISSN: 1545-9985