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EMD-16144
Structure of the SARS-CoV-2 spike glycoprotein in complex with the macrocyclic peptide S1B3inL1
EMD-16144
Single-particle3.2 Å
Deposition: 15/11/2022Map released: 28/06/2023
Last modified: 05/07/2023
Sample Organism:
synthetic construct,
Severe acute respiratory syndrome coronavirus 2,
Tequatrovirus T4
Sample: SARS-CoV-2 spike glycoprotein in complex with the macrocyclic peptide S1B3inL1
Fitted models: 8bon
Deposition Authors: Hurdiss DL
,
Drulyte I
Sample: SARS-CoV-2 spike glycoprotein in complex with the macrocyclic peptide S1B3inL1
Fitted models: 8bon
Deposition Authors: Hurdiss DL
,
Drulyte I
A broad-spectrum macrocyclic peptide inhibitor of the SARS-CoV-2 spike protein.
Thijssen V,
Hurdiss DL ,
Debski-Antoniak OJ,
Spence MA,
Franck C ,
Norman A ,
Aggarwal A,
Mokiem NJ,
van Dongen DAA,
Vermeir SW ,
Liu M ,
Li W ,
Chatziandreou M,
Donselaar T,
Du W ,
Drulyte I ,
Bosch BJ,
Snijder J,
Turville SG,
Payne RJ ,
Jackson CJ,
van Kuppeveld FJM,
Jongkees SAK
(2023) PNAS , 120 , e2303292120 - e2303292120
,
Debski-Antoniak OJ,
Spence MA,
Franck C ,
Norman A ,
Aggarwal A,
Mokiem NJ,
van Dongen DAA,
Vermeir SW ,
Liu M ,
Li W ,
Chatziandreou M,
Donselaar T,
Du W ,
Drulyte I ,
Bosch BJ,
Snijder J,
Turville SG,
Payne RJ ,
Jackson CJ,
van Kuppeveld FJM,
Jongkees SAK
(2023) PNAS , 120 , e2303292120 - e2303292120
Grant Support:
- Innovative Medicines Initiative: 101005077 (Switzerland)