Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-16010

Single-particle
5.92 Å
EMD-16010
3D View Gallery
Deposition: 21/10/2022
Map released: 08/03/2023
Last modified: 16/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-16010
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8bev summary report (pdf.gz) Map and 8bev FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of SARS-CoV-2 spike (HexaPro variant) in complex with nanobody W25 (map 3, focus refinement on RBD, W25 and adjacent NTD)

EMD-16010

Single-particle
5.92 Å
EMD-16010
3D View Gallery
Deposition: 21/10/2022
Map released: 08/03/2023
Last modified: 16/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Severe acute respiratory syndrome coronavirus 2, Vicugna pacos
Sample: Severe acute respiratory syndrome coronavirus 2 spike protein in complex with nanobody W25
Fitted models: 8bev

Deposition Authors: Lauer S , Spahn CMT , Schwefel D
A nanobody recognizes a unique conserved epitope and potently neutralizes SARS-CoV-2 omicron variants.
Modhiran N, Lauer SM , Amarilla AA, Hewins P, Lopes van den Broek SI , Low YS, Thakur N, Liang B , Nieto GV, Jung J, Paramitha D, Isaacs A, Sng JDJ, Song D, Jorgensen JT, Cheuquemilla Y, Burger J, Andersen IV , Himelreichs J, Jara R , MacLoughlin R, Miranda-Chacon Z , Chana-Cuevas P, Kramer V, Spahn C, Mielke T, Khromykh AA, Munro T, Jones ML , Young PR, Chappell K, Bailey D, Kjaer A , Herth MM, Jurado KA, Schwefel D , Rojas-Fernandez A , Watterson D
(2023) iScience , 26 , 107085 - 107085
PUBMED: 37361875
DOI: doi:10.1016/j.isci.2023.107085
ISSN: 2589-0042