Electron Microscopy Data Bank

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EMD-15541

Single-particle
4.4 Å

3D View Gallery

Deposition: 05/08/2022
Map released: 01/03/2023
Last modified: 15/03/2023

Overview 3D View Sample Experiment Validation Additional data Links

EMD-15541

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Beta SARS-CoV-2 Spike bound to mouse ACE2 (two up, full)

EMD-15541

Single-particle
4.4 Å
EMD-15541

3D View Gallery

Deposition: 05/08/2022
Map released: 01/03/2023
Last modified: 15/03/2023

Overview 3D View Sample Experiment Validation Additional data Links

Sample Organism: Severe acute respiratory syndrome coronavirus 2
Sample: Beta SARS-CoV-2 Spike bound to mouse ACE2

Deposition Authors: Ni D, Lau K, Turelli P, Beckert B, Nazarov S, Myasnikov A, Trono D, Stahlberg H, Pojer F, Uchikawa E

Cryo-EM structures and binding of mouse and human ACE2 to SARS-CoV-2 variants of concern indicate that mutations enabling immune escape could expand host range

Ni D, Turelli P, Beckert B, Nazarov S, Uchikawa E, Myasnikov A, Pojer F, Trono D, Stahlberg H, Lau K
(2023) PLoS Pathog

DOI: doi:10.1371/journal.ppat.1011206
ISSN: 1553-7374

Secondary citations:

Ni D, Turelli P, Beckert B, Nazarov S, Uchikawa E, Myasnikov A, Pojer F, Trono D, Stahlberg H & Lau K. (2023) Cryo-EM structures and binding of mouse and human ACE2 to SARS-CoV-2 variants of concern indicate that mutations enabling immune escape could expand host range. bioRxiv,

Grant Support:

Swiss National Science Foundation: NCCR transcure (Switzerland)