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EMD-15225
beta-2-microglobulin D76N amyloid fibril form 2PFa
EMD-15225
Helical reconstruction3.0 Å
Deposition: 21/06/2022Map released: 22/03/2023
Last modified: 20/11/2024
Sample Organism:
Homo sapiens
Sample: Amyloid fibril polymorph 2PFa of the beta-2-microglobulin D76N variant.
Fitted models: 8a7t
Deposition Authors: Wilkinson M
,
Gallardo R ,
Guthertz N ,
Martinez RM ,
Radford SE ,
Ranson NA
Sample: Amyloid fibril polymorph 2PFa of the beta-2-microglobulin D76N variant.
Fitted models: 8a7t
Deposition Authors: Wilkinson M
,
Gallardo R ,
Guthertz N ,
Martinez RM ,
Radford SE ,
Ranson NA
Disease-relevant beta 2 -microglobulin variants share a common amyloid fold.
Wilkinson M ,
Gallardo RU ,
Martinez RM ,
Guthertz N ,
So M ,
Aubrey LD,
Radford SE ,
Ranson NA
(2023) Nat Commun , 14 , 1190 - 1190
,
Gallardo RU ,
Martinez RM ,
Guthertz N ,
So M ,
Aubrey LD,
Radford SE ,
Ranson NA
(2023) Nat Commun , 14 , 1190 - 1190
Grant Support:
- Wellcome Trust: (United Kingdom)
- Medical Research Council (MRC, United Kingdom): (United Kingdom)
- Royal Society: (United Kingdom)