EMD-15022

Single-particle
2.68 Å
EMD-15022
3D View Gallery
Deposition: 24/05/2022
Map released: 07/06/2023
Last modified: 24/07/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-15022

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7zyg summary report (pdf.gz) Map-7zyg FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

CryoEM structure of Ku heterodimer bound to DNA, PAXX and XLF

EMD-15022

Single-particle
2.68 Å
EMD-15022
3D View Gallery
Deposition: 24/05/2022
Map released: 07/06/2023
Last modified: 24/07/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Ku70/80 hetero dimer bound to DNA, PAXX and XLF
Fitted models: 7zyg

Deposition Authors: Hardwick SW , Kefala-Stavridi A, Chirgadze DY , Blundell TL , Chaplin AK
PAXX binding to the NHEJ machinery explains functional redundancy with XLF.
Seif-El-Dahan M, Kefala-Stavridi A, Frit P , Hardwick SW , Chirgadze DY , Maia De Oliviera T , Britton S , Barboule N, Bossaert M , Pandurangan AP , Meek K , Blundell TL , Ropars V, Calsou P , Charbonnier JB , Chaplin AK
(2023) Sci Adv , 9 , eadg2834 - eadg2834
PUBMED: 37256950
DOI: doi:10.1126/sciadv.adg2834
ISSN: 2375-2548
Grant Support: