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EMD-14719

Single-particle
2.61 Å
EMD-14719 Deposition: 05/04/2022
Map released: 09/11/2022
Last modified: 13/12/2023
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-14719

FANCD2 Middle and C-terminal domains with USP1-NTE (focused refinement)

EMD-14719

Single-particle
2.61 Å
EMD-14719 Deposition: 05/04/2022
Map released: 09/11/2022
Last modified: 13/12/2023
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: FANCD2 mono-ubiquitinated on K561

Deposition Authors: Rennie ML , Walden H
Cryo-EM reveals a mechanism of USP1 inhibition through a cryptic binding site.
Rennie ML , Arkinson C, Chaugule VK, Walden H
(2022) Sci Adv , 8 , eabq6353 - eabq6353
PUBMED: 36170365
DOI: doi:10.1126/sciadv.abq6353
ISSN: 2375-2548