EMD-14470
Structure of yeast RNA Polymerase III-Ty1 integrase complex at 2.7 A (focus subunit C11, no C11 C-terminal Zn-ribbon in the funnel pore).
EMD-14470
Single-particle2.76 Å
Deposition: 01/03/2022Map released: 05/04/2023
Last modified: 09/07/2025
Sample Organism:
Saccharomyces cerevisiae S288C
Sample: Cryo-EM structure of the crosslinked RNA Polymerase III-Ty1 integrase complex at 2.7 A (focus subunit C11, no C11 C-terminal Zn-ribbon in the funnel pore)
Fitted models: 7z31
Deposition Authors: Nguyen PQ
,
Huecas S ,
Plaza-Pegueroles A ,
Fernandez-Tornero C
Sample: Cryo-EM structure of the crosslinked RNA Polymerase III-Ty1 integrase complex at 2.7 A (focus subunit C11, no C11 C-terminal Zn-ribbon in the funnel pore)
Fitted models: 7z31
Deposition Authors: Nguyen PQ
,
Huecas S ,
Plaza-Pegueroles A ,
Fernandez-Tornero C
Structural basis of Ty1 integrase tethering to RNA polymerase III for targeted retrotransposon integration.
Nguyen PQ ,
Huecas S ,
Asif-Laidin A ,
Plaza-Pegueroles A ,
Capuzzi B ,
Palmic N,
Conesa C,
Acker J ,
Reguera J,
Lesage P ,
Fernandez-Tornero C
(2023) Nat Commun , 14 , 1729 - 1729
,
Huecas S ,
Asif-Laidin A ,
Plaza-Pegueroles A ,
Capuzzi B ,
Palmic N,
Conesa C,
Acker J ,
Reguera J,
Lesage P ,
Fernandez-Tornero C
(2023) Nat Commun , 14 , 1729 - 1729
Grant Support:
- European Molecular Biology Organization (EMBO): 8023 (European Union)
- Fondation ARC: ARCDOC42020010001355 (France)
- Agence Nationale de la Recherche (ANR): ANR-17-CE11-0025 (France)
- Spanish Ministry of Science, Innovation, and Universities: BFU2017-87397-P (Spain)
- Spanish National Research Council: 2020AEP152 (Spain)
- European Regional Development Fund: PID2020-116722GB-I00 (European Union)