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EMD-14121

Single-particle
2.1 Å
EMD-14121
3D View Gallery
Deposition: 06/01/2022
Map released: 18/01/2023
Last modified: 12/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-14121
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7qq3 summary report (pdf.gz) Map and 7qq3 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of the E.coli 50S ribosomal subunit in complex with the antibiotic Myxovalargin A.

EMD-14121

Single-particle
2.1 Å
EMD-14121
3D View Gallery
Deposition: 06/01/2022
Map released: 18/01/2023
Last modified: 12/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Escherichia coli K-12, Escherichia coli, Myxococcus fulvus
Sample: Cryo-EM structure of the E.coli 50S ribosomal subunit in complex with the antibiotic Myxovalargin A.
Fitted models: 7qq3

Deposition Authors: Koller TO , Beckert B, Wilson DN
The Myxobacterial Antibiotic Myxovalargin: Biosynthesis, Structural Revision, Total Synthesis, and Molecular Characterization of Ribosomal Inhibition.
Koller TO , Scheid U, Kosel T, Herrmann J , Krug D , Boshoff HIM , Beckert B, Evans JC , Schlemmer J, Sloan B, Weiner DM, Via LE, Moosa A , Ioerger TR, Graf M, Zinshteyn B, Abdelshahid M, Nguyen F, Arenz S, Gille F, Siebke M, Seedorf T, Plettenburg O , Green R, Warnke AL , Ullrich J, Warrass R, Barry 3rd CE , Warner DF , Mizrahi V , Kirschning A , Wilson DN , Muller R
(2023) J Am Chem Soc , 145 , 851 - 863
PUBMED: 36603206
DOI: doi:10.1021/jacs.2c08816
ISSN: 1520-5126
ASTM: JACSAT
Grant Support: