EMD-14113
Structure of the human 48S initiation complex in open state (h48S AUG open)
EMD-14113
Single-particle4.7 Å
Deposition: 03/01/2022Map released: 11/05/2022
Last modified: 23/10/2024
Sample Organism:
Homo sapiens
Sample: Human 48S initiation complex 40S-eIF1-eIF1A-eIF2-eIF3-tRNA-Met-mRNA
Fitted models: 7qp6
Deposition Authors: Yi S-H, Petrychenko V
,
Schliep JE ,
Goyal A ,
Linden A ,
Chari A ,
Urlaub H ,
Stark H ,
Rodnina MV ,
Adio S ,
Fischer N
Sample: Human 48S initiation complex 40S-eIF1-eIF1A-eIF2-eIF3-tRNA-Met-mRNA
Fitted models: 7qp6
Deposition Authors: Yi S-H, Petrychenko V
,
Schliep JE ,
Goyal A ,
Linden A ,
Chari A ,
Urlaub H ,
Stark H ,
Rodnina MV ,
Adio S ,
Fischer N
Conformational rearrangements upon start codon recognition in human 48S translation initiation complex.
Yi SH ,
Petrychenko V ,
Schliep JE ,
Goyal A ,
Linden A ,
Chari A ,
Urlaub H ,
Stark H ,
Rodnina MV ,
Adio S ,
Fischer N
(2022) Nucleic Acids Res , 50 , 5282 - 5298
,
Petrychenko V ,
Schliep JE ,
Goyal A ,
Linden A ,
Chari A ,
Urlaub H ,
Stark H ,
Rodnina MV ,
Adio S ,
Fischer N
(2022) Nucleic Acids Res , 50 , 5282 - 5298
Grant Support:
- German Research Foundation (DFG): Leibniz Prize (to M.V.R.) & SFB 860 (Germany)
- Max Planck Society: (Germany)