EMD-13795

Helical reconstruction
3.7 Å
EMD-13795
3D View Gallery
Deposition: 28/10/2021
Map released: 22/03/2023
Last modified: 04/10/2023
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-13795

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7q3u summary report (pdf.gz) Map-7q3u FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of TDP43 core peptide amyloid fiber

EMD-13795

Helical reconstruction
3.7 Å
EMD-13795
3D View Gallery
Deposition: 28/10/2021
Map released: 22/03/2023
Last modified: 04/10/2023
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Helical filament from TDP43 core peptide
Fitted models: 7q3u

Deposition Authors: Nazarov S, Lashuel H
Seeding the aggregation of TDP-43 requires post-fibrillization proteolytic cleavage.
Kumar ST , Nazarov S, Porta S, Maharjan N, Cendrowska U, Kabani M, Finamore F, Xu Y, Lee VM , Lashuel HA
(2023) Nat Neurosci , 26 , 983 - 996
PUBMED: 37248338
DOI: doi:10.1038/s41593-023-01341-4
ISSN: 1097-6256
Grant Support: