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EMD-13594
Cryo-EM structure of Saccharomyces cerevisiae TOROID (TORC1 Organized in Inhibited Domains).
EMD-13594
Single-particle3.87 Å
Deposition: 17/09/2021Map released: 18/01/2023
Last modified: 23/10/2024
Sample Organism:
Saccharomyces cerevisiae
Sample: TORC1 Organized in Inhibited Domains (TOROID)
Fitted models: 7pqh
Deposition Authors: Felix J
,
Prouteau M ,
Bourgoint C ,
Bonadei L,
Desfosses A ,
Gabus C,
Sadian Y,
Savvides SN ,
Gutsche I ,
Loewith R
Sample: TORC1 Organized in Inhibited Domains (TOROID)
Fitted models: 7pqh
Deposition Authors: Felix J
,
Prouteau M ,
Bourgoint C ,
Bonadei L,
Desfosses A ,
Gabus C,
Sadian Y,
Savvides SN ,
Gutsche I ,
Loewith R
EGOC inhibits TOROID polymerization by structurally activating TORC1.
Prouteau M ,
Bourgoint C ,
Felix J ,
Bonadei L,
Sadian Y,
Gabus C,
Savvides SN ,
Gutsche I ,
Desfosses A ,
Loewith R
(2023) Nat Struct Mol Biol , 30 , 273 - 285
,
Bourgoint C ,
Felix J ,
Bonadei L,
Sadian Y,
Gabus C,
Savvides SN ,
Gutsche I ,
Desfosses A ,
Loewith R
(2023) Nat Struct Mol Biol , 30 , 273 - 285
Grant Support:
- European Research Council (ERC): 834394 (European Union)
- Swiss National Science Foundation: 179517 (European Union)
- H2020 Marie Curie Actions of the European Commission: 789385 (European Union)
- European Research Council (ERC): 64778 (European Union)