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EMD-12694
Cryo-EM structure of an Escherichia coli TnaC(R23F)-ribosome complex stalled in response to L-tryptophan
EMD-12694
Single-particle2.4 Å
Deposition: 29/03/2021Map released: 01/09/2021
Last modified: 12/03/2025
Sample Organism:
Escherichia coli (strain K12)
Sample: 70S ribosome stalled during translation of TnaC(R23F) with Pro24 in the P-site.
Fitted models: 7o1a
Deposition Authors: van der Stel AX
,
Gordon ER
Sample: 70S ribosome stalled during translation of TnaC(R23F) with Pro24 in the P-site.
Fitted models: 7o1a
Deposition Authors: van der Stel AX
,
Gordon ER
Structural basis for the tryptophan sensitivity of TnaC-mediated ribosome stalling.
van der Stel AX ,
Gordon ER ,
Sengupta A ,
Martinez AK,
Klepacki D,
Perry TN,
Herrero Del Valle A ,
Vazquez-Laslop N ,
Sachs MS ,
Cruz-Vera LR ,
Innis CA
(2021) Nat Commun , 12 , 5340 - 5340
,
Gordon ER ,
Sengupta A ,
Martinez AK,
Klepacki D,
Perry TN,
Herrero Del Valle A ,
Vazquez-Laslop N ,
Sachs MS ,
Cruz-Vera LR ,
Innis CA
(2021) Nat Commun , 12 , 5340 - 5340
Grant Support:
- European Research Council (ERC): 724040 (France)
- National Science Foundation (NSF, United States): MCB-1158271 (United States)
- National Science Foundation (NSF, United States): MCB-1951405 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R01 GM47498 (United States)