EMD-12367

Single-particle
3.8 Å
EMD-12367
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Deposition: 14/02/2021
Map released: 25/08/2021
Last modified: 09/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-12367
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7niw summary report (pdf.gz) Map and 7niw FULL report (pdf.gz)
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Nanodisc reconstituted human ABCB4 in complex with 4B1-Fab (posaconazole-bound, inward-open conformation)

EMD-12367

Single-particle
3.8 Å
EMD-12367
3D View Gallery
Deposition: 14/02/2021
Map released: 25/08/2021
Last modified: 09/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Nanodisc reconstituted human ABCB4 in complex with 4B1-Fab (posaconazole-bound, inward-open conformation)
Fitted models: 7niw

Deposition Authors: Nosol K , Locher KP
Structures of ABCB4 provide insight into phosphatidylcholine translocation.
Nosol K , Bang-Sorensen R, Irobalieva RN , Erramilli SK, Stieger B , Kossiakoff AA, Locher KP
(2021) PNAS , 118
PUBMED: 34385322
DOI: doi:10.1073/pnas.2106702118
ISSN: 1091-6490
ASTM: PNASA6