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EMD-12257

Helical reconstruction
4.4 Å
EMD-12257
3D View Gallery
Deposition: 25/01/2021
Map released: 13/10/2021
Last modified: 10/07/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-12257
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7nb8 summary report (pdf.gz) Map and 7nb8 FULL report (pdf.gz)
EMICSS annotations (xml)

Plasmodium falciparum kinesin-5 motor domain without nucleotide, complexed with 14 protofilament microtubule.

EMD-12257

Helical reconstruction
4.4 Å
EMD-12257
3D View Gallery
Deposition: 25/01/2021
Map released: 13/10/2021
Last modified: 10/07/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Sus scrofa, Plasmodium falciparum (isolate 3D7)
Sample: 14 protofilament microtubule of alpha/beta-tubulin dimers, with kinesin-5 motor domain bound 1:1 to tubulin dimers.
Fitted models: 7nb8

Deposition Authors: Cook AD , Roberts A
Cryo-EM structure of a microtubule-bound parasite kinesin motor and implications for its mechanism and inhibition.
Cook AD , Roberts AJ, Atherton J , Tewari R , Topf M , Moores CA
(2021) J Biol Chem , 297 , 101063 - 101063
PUBMED: 34375637
DOI: doi:10.1016/j.jbc.2021.101063
ISSN: 1083-351X
ASTM: JBCHA3