EMD-12143

Single-particle
3.37 Å
EMD-12143
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Deposition: 21/12/2020
Map released: 22/09/2021
Last modified: 10/07/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-12143
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Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
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ASCT2 in the presence of the inhibitor ERA-21 in the outward-open conformation.

EMD-12143

Single-particle
3.37 Å
EMD-12143
3D View Gallery
Deposition: 21/12/2020
Map released: 22/09/2021
Last modified: 10/07/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: ASCT2 in the presence of the inhibitor ERA-21 in the outward-open conformation.
Fitted models: 7bct

Deposition Authors: Garibsingh RA , Ndaru E
Rational design of ASCT2 inhibitors using an integrated experimental-computational approach.
Garibsingh RA , Ndaru E , Garaeva AA , Shi Y, Zielewicz L, Zakrepine P, Bonomi M , Slotboom DJ , Paulino C , Grewer C , Schlessinger A
(2021) PNAS , 118
PUBMED: 34507995
DOI: doi:10.1073/pnas.2104093118
ISSN: 1091-6490
ASTM: PNASA6