EMD-11937

Helical reconstruction
3.4 Å
EMD-11937
3D View Gallery
Deposition: 15/11/2020
Map released: 24/11/2021
Last modified: 01/12/2021
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-11937
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CryoEM structure of the MDA5-dsRNA filament in complex with ADP with 92-degree helical twist

EMD-11937

Helical reconstruction
3.4 Å
EMD-11937
3D View Gallery
Deposition: 15/11/2020
Map released: 24/11/2021
Last modified: 01/12/2021
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Pseudomonas virus phi6, Mus musculus
Sample: MDA5-dsRNA filament in complex with ADP

Deposition Authors: Yu Q , Modis Y
MDA5 disease variant M854K prevents ATP-dependent structural discrimination of viral and cellular RNA.
Yu Q , Herrero Del Valle A , Singh R , Modis Y
(2021) Nat Commun , 12 , 6668 - 6668
PUBMED: 34795277
DOI: doi:10.1038/s41467-021-27062-5
ISSN: 2041-1723