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EMD-11005

Single-particle
4.7 Å
EMD-11005
3D View Gallery
Deposition: 06/05/2020
Map released: 23/09/2020
Last modified: 09/12/2020
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-11005
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3D volume (map.gz) Experimental metadata (xml)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
EMICSS annotations (xml)

Structure of human cGAS bound to the nucleosome (focused refinement of cGAS-NCP subcomplex)

EMD-11005

Single-particle
4.7 Å
EMD-11005
3D View Gallery
Deposition: 06/05/2020
Map released: 23/09/2020
Last modified: 09/12/2020
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Cryo EM structure of cGAS-NCP1 complex

Deposition Authors: Pathare GR, Cavadini S, Kempf G, Thoma NH
Structural mechanism of cGAS inhibition by the nucleosome.
Pathare GR , Decout A , Gluck S , Cavadini S, Makasheva K , Hovius R , Kempf G, Weiss J , Kozicka Z , Guey B , Melenec P , Fierz B , Thoma NH , Ablasser A
(2020) Nature , 587 , 668 - 672
PUBMED: 32911482
DOI: doi:10.1038/s41586-020-2750-6
ISSN: 1476-4687
ASTM: NATUAS