EMD-10578

Single-particle
9.3 Å
EMD-10578
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Deposition: 27/12/2019
Map released: 19/02/2020
Last modified: 04/03/2020
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-10578
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Ubiquitin Ligation to substrate by a cullin-RING E3 ligase: NEDD8-CUL1-RBX1 SKP1-dimeric bTRCP2-IkBa-(UB)~UBE2D2

EMD-10578

Single-particle
9.3 Å
EMD-10578
3D View Gallery
Deposition: 27/12/2019
Map released: 19/02/2020
Last modified: 04/03/2020
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Ubiquitin Ligation to substrate by a cullin-RING E3 ligase: NEDD8-CUL1-RBX1 SKP1-dimeric bTRCP2-IkB-(UB)~UBE2D2

Deposition Authors: Baek K, Prabu JR, Schulman BA
NEDD8 nucleates a multivalent cullin-RING-UBE2D ubiquitin ligation assembly.
Baek K, Krist DT, Prabu JR, Hill S, Klugel M, Neumaier LM, von Gronau S, Kleiger G, Schulman BA
(2020) Nature , 578 , 461 - 466
PUBMED: 32051583
DOI: doi:10.1038/s41586-020-2000-y
ISSN: 1476-4687
ASTM: NATUAS
Grant Support: