EMD-0061

Single-particle
3.91 Å
EMD-0061
3D View Gallery
Deposition: 18/06/2018
Map released: 19/12/2018
Last modified: 15/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-0061

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-6gtc summary report (pdf.gz) Map-6gtc FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Transition state structure of Cpf1(Cas12a)I1 conformation

EMD-0061

Single-particle
3.91 Å
EMD-0061
3D View Gallery
Deposition: 18/06/2018
Map released: 19/12/2018
Last modified: 15/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Francisella tularensis subsp. novicida U112
Sample: Transition state complex I1 conformation
Fitted models: 6gtc

Deposition Authors: Mesa P, Montoya G
Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity.
Stella S , Mesa P, Thomsen J , Paul B , Alcon P , Jensen SB , Saligram B, Moses ME , Hatzakis NS , Montoya G
(2018) Cell , 175 , 1856 - 1871.e21
PUBMED: 30503205
DOI: doi:10.1016/j.cell.2018.10.045
ISSN: 1097-4172
Grant Support: