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sample_name:"bCNT3 trimer"

Filter By

Current Database

  • EMDB [24]

Current status

  • REL [24]

Sample type

  • Complex [24]
  • Protein [24]
  • Ligand [11]

Organism

  • Bos taurus [24]

EM Method

  • Single-particle [24]

Resolution

  • ≥ 2Å and < 3Å [7]
  • ≥ 3Å and < 4Å [12]
  • ≥ 4Å and < 5Å [3]
  • ≥ 5Å and < 6Å [1]
  • ≥ 6Å and < 8Å [1]

Model molecular weight

  • 100-250 kDa [11]

Release Date

  • 2024 [24]

Author by name

  • Borgnia MJ [24]
  • Fedor JG [24]
  • Im W [24]
  • Kong L [24]
  • Lee S-Y [24]
  • Lee SY [24]
  • Sharma K [24]
  • Suo Y [24]
  • Wright NJ [24]
  • Yin Y [24]
  • Zhang F [24]

Author by ORCID

  • Im W [24]
  • Borgnia MJ [24]
  • Lee SY [24]
  • Kong L [24]
  • Sharma K [24]
  • Wright NJ [24]
  • Suo Y [24]

Journal

  • NAT CHEM BIOL [24]

Software

  • CRYOSPARC [24]

Microscope

  • FEI TITAN KRIOS [24]

Electron Source

  • FIELD EMISSION GUN [24]

Film or detector model

  • GATAN K3 BIOQUANTUM 6K X 4K [24]

External links

  • AlphaFold DB [23]
  • PDBe-Kb [23]
  • UniProt [23]
  • InterPro [11]
  • PDB [11]
  • Pfam [11]
  • Gene Ontology [10]
  • ChEBI [9]
  • DrugBank [6]
  • ChEMBL [5]
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Showing 1 - 10 of 24. Page 1 of 3
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EMD-41730
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3D View
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Ribavirin
Release date: March 13, 2024
Resolution: 2.54 Å
EM Method: Single-particle
Fitted PDBs: 8tz1
Q-score: 0.596

Wright NJ, Zhang F, Suo Y, Kong L, Yin Y, Fedor JG, Sharma K, Borgnia MJ, Im W, Lee SY

Nat Chem Biol (2024) 20 pp. 1144-1153 [ DOI: doi:10.1038/s41589-024-01559-8 Pubmed: 38418906 ]

EMD-41731
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3D View
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in MSP2N2 nanodiscs, apo state
Release date: March 13, 2024
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8tz2
Q-score: 0.555

Wright NJ, Zhang F, Suo Y, Kong L, Yin Y, Fedor JG, Sharma K, Borgnia MJ, Im W, Lee SY

Nat Chem Biol (2024) 20 pp. 1144-1153 [ DOI: doi:10.1038/s41589-024-01559-8 Pubmed: 38418906 ]

EMD-41732
Download Map
3D View
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with GS-441524, consensus reconstruction
Release date: March 13, 2024
Resolution: 2.31 Å
EM Method: Single-particle
Fitted PDBs: 8tz3
Q-score: 0.649

Wright NJ, Zhang F, Suo Y, Kong L, Yin Y, Fedor JG, Sharma K, Borgnia MJ, Im W, Lee SY

Nat Chem Biol (2024) 20 pp. 1144-1153 [ DOI: doi:10.1038/s41589-024-01559-8 Pubmed: 38418906 ]

EMD-41733
Download Map
3D View
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with GS-441524, subset reconstruction
Release date: March 13, 2024
Resolution: 3.23 Å
EM Method: Single-particle
Fitted PDBs: 8tz4
Q-score: 0.503

Wright NJ, Zhang F, Suo Y, Kong L, Yin Y, Fedor JG, Sharma K, Borgnia MJ, Im W, Lee SY

Nat Chem Biol (2024) 20 pp. 1144-1153 [ DOI: doi:10.1038/s41589-024-01559-8 Pubmed: 38418906 ]

EMD-41734
Download Map
3D View
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with N-hydroxycytidine
Release date: March 13, 2024
Resolution: 2.74 Å
EM Method: Single-particle
Fitted PDBs: 8tz5
Q-score: 0.559

Wright NJ, Zhang F, Suo Y, Kong L, Yin Y, Fedor JG, Sharma K, Borgnia MJ, Im W, Lee SY

Nat Chem Biol (2024) 20 pp. 1144-1153 [ DOI: doi:10.1038/s41589-024-01559-8 Pubmed: 38418906 ]

EMD-41735
Download Map
3D View
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with PSI-6206
Release date: March 13, 2024
Resolution: 2.69 Å
EM Method: Single-particle
Fitted PDBs: 8tz6
Q-score: 0.555

Wright NJ, Zhang F, Suo Y, Kong L, Yin Y, Fedor JG, Sharma K, Borgnia MJ, Im W, Lee SY

Nat Chem Biol (2024) 20 pp. 1144-1153 [ DOI: doi:10.1038/s41589-024-01559-8 Pubmed: 38418906 ]

EMD-41736
Download Map
3D View
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 1, INT1-INT1-INT1 conformation
Release date: March 13, 2024
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8tz7
Q-score: 0.53

Wright NJ, Zhang F, Suo Y, Kong L, Yin Y, Fedor JG, Sharma K, Borgnia MJ, Im W, Lee SY

Nat Chem Biol (2024) 20 pp. 1144-1153 [ DOI: doi:10.1038/s41589-024-01559-8 Pubmed: 38418906 ]

EMD-41737
Download Map
3D View
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 1, INT1-INT1-INT3 conformation
Release date: March 13, 2024
Resolution: 3.19 Å
EM Method: Single-particle
Fitted PDBs: 8tz8
Q-score: 0.504

Wright NJ, Zhang F, Suo Y, Kong L, Yin Y, Fedor JG, Sharma K, Borgnia MJ, Im W, Lee SY

Nat Chem Biol (2024) 20 pp. 1144-1153 [ DOI: doi:10.1038/s41589-024-01559-8 Pubmed: 38418906 ]

EMD-41738
Download Map
3D View
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 2, INT2-INT2-INT2 conformation
Release date: March 13, 2024
Resolution: 3.67 Å
EM Method: Single-particle
Fitted PDBs: 8tz9
Q-score: 0.387

Wright NJ, Zhang F, Suo Y, Kong L, Yin Y, Fedor JG, Sharma K, Borgnia MJ, Im W, Lee SY

Nat Chem Biol (2024) 20 pp. 1144-1153 [ DOI: doi:10.1038/s41589-024-01559-8 Pubmed: 38418906 ]

EMD-41739
Download Map
3D View
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 2, INT2-INT1-INT1 conformation
Release date: March 13, 2024
Resolution: 3.43 Å
EM Method: Single-particle
Fitted PDBs: 8tza
Q-score: 0.449

Wright NJ, Zhang F, Suo Y, Kong L, Yin Y, Fedor JG, Sharma K, Borgnia MJ, Im W, Lee SY

Nat Chem Biol (2024) 20 pp. 1144-1153 [ DOI: doi:10.1038/s41589-024-01559-8 Pubmed: 38418906 ]

Sort by: Download
Showing 1 - 10 of 24. Page 1 of 3
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [24]

Current status

  • REL [24]

Sample type

  • Complex [24]
  • Protein [24]
  • Ligand [11]

Organism

  • Bos taurus [24]

EM Method

  • Single-particle [24]

Resolution

  • ≥ 2Å and < 3Å [7]
  • ≥ 3Å and < 4Å [12]
  • ≥ 4Å and < 5Å [3]
  • ≥ 5Å and < 6Å [1]
  • ≥ 6Å and < 8Å [1]

Model molecular weight

  • 100-250 kDa [11]

Release Date

  • 2024 [24]

Author by name

  • Borgnia MJ [24]
  • Fedor JG [24]
  • Im W [24]
  • Kong L [24]
  • Lee S-Y [24]
  • Lee SY [24]
  • Sharma K [24]
  • Suo Y [24]
  • Wright NJ [24]
  • Yin Y [24]
  • Zhang F [24]

Author by ORCID

  • Im W [24]
  • Borgnia MJ [24]
  • Lee SY [24]
  • Kong L [24]
  • Sharma K [24]
  • Wright NJ [24]
  • Suo Y [24]

Journal

  • NAT CHEM BIOL [24]

Software

  • CRYOSPARC [24]

Microscope

  • FEI TITAN KRIOS [24]

Electron Source

  • FIELD EMISSION GUN [24]

Film or detector model

  • GATAN K3 BIOQUANTUM 6K X 4K [24]

External links

  • AlphaFold DB [23]
  • PDBe-Kb [23]
  • UniProt [23]
  • InterPro [11]
  • PDB [11]
  • Pfam [11]
  • Gene Ontology [10]
  • ChEBI [9]
  • DrugBank [6]
  • ChEMBL [5]