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sample_name:"XPR1-E622A/F623A mutant in complex with InsP6"

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  • Dai Z [1]
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  • Wang W [1]
  • Liang L [1]
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EMD-60861
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Cryo-EM structure of human XPR1-E622A/F623A mutant in complex with InsP6 in inward-facing state in the presence of 10 mM KH2PO4
Release date: April 2, 2025
Resolution: 3.03 Å
EM Method: Single-particle
Fitted PDBs: 9itg
Q-score: 0.478

Zuo P, Wang W, Dai Z, Zheng J, Yu S, Wang G, Yin Y, Liang L, Yin Y

Nat Commun (2025) 16 pp. 2879-2879 [ DOI: doi:10.1038/s41467-025-58200-y Pubmed: 40128258 ]

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Filter By

Current Database

  • EMDB [1]

Current status

  • REL [1]

Sample type

  • Complex [1]
  • Ligand [1]
  • Protein [1]

Organism

  • Homo sapiens [1]

EM Method

  • Single-particle [1]

Resolution

  • ≥ 3Å and < 4Å [1]

Model molecular weight

  • 100-250 kDa [1]

Release Date

  • 2025 [1]

Author by name

  • Dai Z [1]
  • Liang L [1]
  • Wang G [1]
  • Wang W [1]
  • Yin Y [1]
  • Yu S [1]
  • Zheng J [1]
  • Zuo P [1]

Author by ORCID

  • Wang W [1]
  • Liang L [1]
  • Dai Z [1]
  • Wang G [1]
  • Zuo P [1]
  • Yin Y [1]
  • Yu S [1]

Journal

  • NAT COMMUN [1]

Microscope

  • FEI TECNAI 20 [1]

Electron Source

  • FIELD EMISSION GUN [1]

Film or detector model

  • FEI FALCON IV 4K X 4K [1]

External links

  • AlphaFold DB [1]
  • ChEBI [1]
  • ChEMBL [1]
  • DrugBank [1]
  • Gene Ontology [1]
  • InterPro [1]
  • PDB [1]
  • PDBe-Kb [1]
  • Pfam [1]
  • UniProt [1]