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sample_name:"Human OCT1"

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Current Database

  • EMDB [5]

Current status

  • REL [5]

Sample type

  • Complex [5]
  • Protein [5]
  • Ligand [4]

Organism

  • Homo sapiens [5]

EM Method

  • Single-particle [5]

Resolution

  • ≥ 2Å and < 3Å [1]
  • ≥ 3Å and < 4Å [4]

Model molecular weight

  • 50-100 kDa [5]

Release Date

  • 2023 [5]

Author by name

  • Brown SHJ [5]
  • O Mara Ml [5]
  • Quinn A [5]
  • Ryan RM [5]
  • Smith NJ [5]
  • Sobti M [5]
  • Stewart AG [5]
  • Vandenberg JI [5]
  • Zeng YC [5]

Author by ORCID

  • Zeng YC [5]
  • Stewart AG [5]
  • Vandenberg JI [5]
  • Smith NJ [5]
  • Ryan RM [5]
  • O'mara ML [5]
  • Brown SHJ [5]
  • Quinn A [5]

Journal

  • NAT COMMUN [5]

Microscope

  • FEI TITAN KRIOS [5]

Electron Source

  • FIELD EMISSION GUN [5]

Film or detector model

  • GATAN K3 6K X 4K [5]

External links

  • AlphaFold DB [5]
  • Gene Ontology [5]
  • InterPro [5]
  • PDB [5]
  • PDBe-Kb [5]
  • Pfam [5]
  • UniProt [5]
  • ChEMBL [4]
  • ChEBI [3]
  • DrugBank [3]
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Showing 1 - 5 of 5. Page 1 of 1
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EMD-40334
Download Map
3D View
Human OCT1 Apo in inward-open conformation
Release date: Oct. 18, 2023
Resolution: 2.92 Å
EM Method: Single-particle
Fitted PDBs: 8sc1
Q-score: 0.52

Zeng YC, Sobti M, Quinn A, Smith NJ, Brown SHJ, Vandenberg JI, Ryan RM, O'Mara ML, Stewart AG

Nat Commun (2023) 14 pp. 6374-6374 [ Pubmed: 37821493 DOI: doi:10.1038/s41467-023-42086-9 ]

EMD-40335
Download Map
3D View
Human OCT1 bound to diltiazem in inward-open conformation
Release date: Oct. 18, 2023
Resolution: 3.36 Å
EM Method: Single-particle
Fitted PDBs: 8sc2
Q-score: 0.452

Zeng YC, Sobti M, Quinn A, Smith NJ, Brown SHJ, Vandenberg JI, Ryan RM, O'Mara ML, Stewart AG

Nat Commun (2023) 14 pp. 6374-6374 [ Pubmed: 37821493 DOI: doi:10.1038/s41467-023-42086-9 ]

EMD-40336
Download Map
3D View
Human OCT1 bound to fenoterol in inward-open conformation
Release date: Oct. 18, 2023
Resolution: 3.24 Å
EM Method: Single-particle
Fitted PDBs: 8sc3
Q-score: 0.425

Zeng YC, Sobti M, Quinn A, Smith NJ, Brown SHJ, Vandenberg JI, Ryan RM, O'Mara ML, Stewart AG

Nat Commun (2023) 14 pp. 6374-6374 [ Pubmed: 37821493 DOI: doi:10.1038/s41467-023-42086-9 ]

EMD-40337
Download Map
3D View
Human OCT1 bound to metformin in inward-open conformation
Release date: Oct. 18, 2023
Resolution: 3.46 Å
EM Method: Single-particle
Fitted PDBs: 8sc4
Q-score: 0.405

Zeng YC, Sobti M, Quinn A, Smith NJ, Brown SHJ, Vandenberg JI, Ryan RM, O'Mara ML, Stewart AG

Nat Commun (2023) 14 pp. 6374-6374 [ Pubmed: 37821493 DOI: doi:10.1038/s41467-023-42086-9 ]

EMD-40339
Download Map
3D View
Human OCT1 bound to thiamine in inward-open conformation
Release date: Oct. 18, 2023
Resolution: 3.13 Å
EM Method: Single-particle
Fitted PDBs: 8sc6
Q-score: 0.496

Zeng YC, Sobti M, Quinn A, Smith NJ, Brown SHJ, Vandenberg JI, Ryan RM, O'Mara ML, Stewart AG

Nat Commun (2023) 14 pp. 6374-6374 [ Pubmed: 37821493 DOI: doi:10.1038/s41467-023-42086-9 ]

Sort by: Download
Showing 1 - 5 of 5. Page 1 of 1
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [5]

Current status

  • REL [5]

Sample type

  • Complex [5]
  • Protein [5]
  • Ligand [4]

Organism

  • Homo sapiens [5]

EM Method

  • Single-particle [5]

Resolution

  • ≥ 2Å and < 3Å [1]
  • ≥ 3Å and < 4Å [4]

Model molecular weight

  • 50-100 kDa [5]

Release Date

  • 2023 [5]

Author by name

  • Brown SHJ [5]
  • O Mara Ml [5]
  • Quinn A [5]
  • Ryan RM [5]
  • Smith NJ [5]
  • Sobti M [5]
  • Stewart AG [5]
  • Vandenberg JI [5]
  • Zeng YC [5]

Author by ORCID

  • Zeng YC [5]
  • Stewart AG [5]
  • Vandenberg JI [5]
  • Smith NJ [5]
  • Ryan RM [5]
  • O'mara ML [5]
  • Brown SHJ [5]
  • Quinn A [5]

Journal

  • NAT COMMUN [5]

Microscope

  • FEI TITAN KRIOS [5]

Electron Source

  • FIELD EMISSION GUN [5]

Film or detector model

  • GATAN K3 6K X 4K [5]

External links

  • AlphaFold DB [5]
  • Gene Ontology [5]
  • InterPro [5]
  • PDB [5]
  • PDBe-Kb [5]
  • Pfam [5]
  • UniProt [5]
  • ChEMBL [4]
  • ChEBI [3]
  • DrugBank [3]