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sample_name:"Heterodimer of PIK3CA with PIK3R1"

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EMD-24081
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Cryo-EM Structure of p110alpha in complex with p85alpha
Release date: Nov. 10, 2021
Resolution: 2.79 Å
EM Method: Single-particle
Fitted PDBs: 7myn
Q-score: 0.472

Liu X, Yang S, Hart JR, Xu Y, Zou X, Zhang H, Zhou Q, Xia T, Zhang Y, Yang D, Wang MW, Vogt PK

PNAS (2021) 118 [ Pubmed: 34725156 DOI: doi:10.1073/pnas.2109327118 ]

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Filter By

Current Database

  • EMDB [1]

Current status

  • REL [1]

Sample type

  • Complex [1]
  • Ligand [1]
  • Protein [1]

Organism

  • Homo sapiens [1]

EM Method

  • Single-particle [1]

Resolution

  • ≥ 2Å and < 3Å [1]

Model molecular weight

  • 100-250 kDa [1]

Release Date

  • 2021 [1]

Author by name

  • Hart JR [1]
  • Liu X [1]
  • Vogt PK [1]
  • Wang MW [1]
  • Xia T [1]
  • Xu Y [1]
  • Yang D [1]
  • Yang S [1]
  • Zhang H [1]
  • Zhang Y [1]
  • Zhou Q [1]
  • Zou X [1]

Author by ORCID

  • Wang MW [1]
  • Zhou Q [1]
  • Hart JR [1]
  • Vogt PK [1]
  • Yang D [1]

Journal

  • PNAS [1]

Microscope

  • FEI TITAN KRIOS [1]

Electron Source

  • OTHER [1]

Film or detector model

  • GATAN K3 6K X 4K [1]

External links

  • AlphaFold DB [1]
  • ChEBI [1]
  • ChEMBL [1]
  • Complex Portal [1]
  • DrugBank [1]
  • Gene Ontology [1]
  • InterPro [1]
  • PDB [1]
  • PDBe-Kb [1]
  • Pfam [1]
  • UniProt [1]