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sample_name:"FLCN-FNIP2-RagA-RagC-Ragulator Complex"

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EMD-0554
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Cryo-EM Structure of the Lysosomal Folliculin Complex FLCN-FNIP2-RagA-RagC-Ragulator
Release date: Nov. 6, 2019
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 6nzd
Q-score: 0.326

Lawrence RE, Fromm SA, Fu Y, Yokom AL, Kim DJ, Thelen AM, Young LN, Lim CY, Samelson AJ, Hurley JH, Zoncu R

Science (2019) 366 pp. 971-977 [ Pubmed: 31672913 DOI: doi:10.1126/science.aax0364 ]

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Filter By

Current Database

  • EMDB [1]

Current status

  • REL [1]

Sample type

  • Complex [1]
  • Ligand [1]
  • Protein [1]

Organism

  • Homo sapiens [1]

EM Method

  • Single-particle [1]

Resolution

  • ≥ 3Å and < 4Å [1]

Model molecular weight

  • 250-500 kDa [1]

Release Date

  • 2019 [1]

Author by name

  • Fromm SA [1]
  • Fu Y [1]
  • Hurley JH [1]
  • Kim DJ [1]
  • Lawrence RE [1]
  • Lim CY [1]
  • Samelson AJ [1]
  • Thelen AM [1]
  • Yokom AL [1]
  • Young LN [1]
  • Zoncu R [1]

Author by ORCID

  • Hurley JH [1]
  • Fu Y [1]
  • Thelen AM [1]
  • Fromm SA [1]
  • Yokom AL [1]
  • Lim CY [1]
  • Zoncu R [1]
  • Lawrence RE [1]
  • Samelson AJ [1]
  • Young LN [1]

Journal

  • SCIENCE [1]

Software

  • CRYOSPARC [1]

Microscope

  • FEI TITAN KRIOS [1]

Electron Source

  • FIELD EMISSION GUN [1]

Film or detector model

  • GATAN K2 SUMMIT 4K X 4K [1]

External links

  • AlphaFold DB [1]
  • ChEBI [1]
  • ChEMBL [1]
  • DrugBank [1]
  • Gene Ontology [1]
  • InterPro [1]
  • PDB [1]
  • PDBe-Kb [1]
  • Pfam [1]
  • UniProt [1]