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sample_name:"DCAF2"

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Current Database

  • EMDB [3]

Current status

  • REL [3]

Sample type

  • Complex [3]
  • Protein [3]
  • Ligand [2]

Organism

  • Homo sapiens [3]

EM Method

  • Single-particle [3]

Resolution

  • ≥ 3Å and < 4Å [3]

Model molecular weight

  • 100-250 kDa [3]

Release Date

  • 2025 [3]

Author by name

  • Cioffi AG [3]
  • Daczkowski CM [3]
  • Erlanson DA [3]
  • Everley RA [3]
  • Hermann JC [3]
  • Lin Y [3]
  • Mcmahon EJ [3]
  • Narayan V [3]
  • Neve RM [3]
  • Shaghafi M [3]
  • Visperas PR [3]
  • Wang W [3]
  • Webster KR [3]

Journal

  • STRUCTURE [3]

Software

  • CRYOSPARC [3]
  • COOT [1]

Microscope

  • TFS KRIOS [3]

Electron Source

  • FIELD EMISSION GUN [3]

Film or detector model

  • GATAN K3 6K X 4K [3]

External links

  • AlphaFold DB [3]
  • Gene Ontology [3]
  • PDB [3]
  • PDBe-Kb [3]
  • Pfam [3]
  • UniProt [3]
  • Complex Portal [1]
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EMD-45224
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3D View
Cryo EM structure of DCAF2
Release date: Oct. 1, 2025
Resolution: 3.36 Å
EM Method: Single-particle
Fitted PDBs: 9c5t
Q-score: 0.442

McMahon EJ, Cioffi AG, Visperas PR, Lin Y, Shaghafi M, Daczkowski CM, Hermann JC, Everley RA, Neve RM, Erlanson DA, Webster KR, Narayan V, Wang W

Structure (2025) 33 pp. 2020-2028.e7 [ Pubmed: 41045927 DOI: doi:10.1016/j.str.2025.09.006 ]

EMD-45225
Download Map
3D View
Cryo EM structure of DCAF2:Compound 1 complex
Release date: Oct. 1, 2025
Resolution: 3.05 Å
EM Method: Single-particle
Fitted PDBs: 9c5u
Q-score: 0.472

McMahon EJ, Cioffi AG, Visperas PR, Lin Y, Shaghafi M, Daczkowski CM, Hermann JC, Everley RA, Neve RM, Erlanson DA, Webster KR, Narayan V, Wang W

Structure (2025) 33 pp. 2020-2028.e7 [ Pubmed: 41045927 DOI: doi:10.1016/j.str.2025.09.006 ]

EMD-45226
Download Map
3D View
Cryo EM structure of a DCAF2:degrader:BRD4 ternary complex
Release date: Oct. 1, 2025
Resolution: 3.36 Å
EM Method: Single-particle
Fitted PDBs: 9c5v
Q-score: 0.338

McMahon EJ, Cioffi AG, Visperas PR, Lin Y, Shaghafi M, Daczkowski CM, Hermann JC, Everley RA, Neve RM, Erlanson DA, Webster KR, Narayan V, Wang W

Structure (2025) 33 pp. 2020-2028.e7 [ Pubmed: 41045927 DOI: doi:10.1016/j.str.2025.09.006 ]

Sort by: Download
Showing 1 - 3 of 3. Page 1 of 1
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [3]

Current status

  • REL [3]

Sample type

  • Complex [3]
  • Protein [3]
  • Ligand [2]

Organism

  • Homo sapiens [3]

EM Method

  • Single-particle [3]

Resolution

  • ≥ 3Å and < 4Å [3]

Model molecular weight

  • 100-250 kDa [3]

Release Date

  • 2025 [3]

Author by name

  • Cioffi AG [3]
  • Daczkowski CM [3]
  • Erlanson DA [3]
  • Everley RA [3]
  • Hermann JC [3]
  • Lin Y [3]
  • Mcmahon EJ [3]
  • Narayan V [3]
  • Neve RM [3]
  • Shaghafi M [3]
  • Visperas PR [3]
  • Wang W [3]
  • Webster KR [3]

Journal

  • STRUCTURE [3]

Software

  • CRYOSPARC [3]
  • COOT [1]

Microscope

  • TFS KRIOS [3]

Electron Source

  • FIELD EMISSION GUN [3]

Film or detector model

  • GATAN K3 6K X 4K [3]

External links

  • AlphaFold DB [3]
  • Gene Ontology [3]
  • PDB [3]
  • PDBe-Kb [3]
  • Pfam [3]
  • UniProt [3]
  • Complex Portal [1]