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sample_name:"CTP synthase"

Filter By

Current Database

  • EMDB [43]

Current status

  • REL [43]

Sample type

  • Protein [41]
  • Complex [36]
  • Ligand [36]
  • Cellular component [6]
  • Sample [1]

Organism

  • Homo sapiens [11]
  • Saccharomyces cerevisiae [10]
  • Drosophila melanogaster [8]
  • Escherichia coli [6]
  • Mycobacterium tuberculosis [4]
  • Mus musculus [3]
  • Escherichia coli [1]

EM Method

  • Single-particle [36]
  • Helical reconstruction [7]

Resolution

  • ≥ 2Å and < 3Å [17]
  • ≥ 3Å and < 4Å [12]
  • ≥ 4Å and < 5Å [1]
  • ≥ 5Å and < 6Å [1]
  • ≥ 6Å and < 8Å [9]
  • ≥ 8Å and < 12Å [3]

Model molecular weight

  • 100-250 kDa [3]
  • 250-500 kDa [22]
  • 500-1000 kDa [8]
  • 1-2 MDa [7]

Release Date

  • 2025 [5]
  • 2024 [3]
  • 2023 [2]
  • 2021 [22]
  • 2020 [2]
  • 2019 [2]
  • 2017 [6]
  • 2014 [1]

Author by name

  • Kollman JM [33]
  • Lynch EM [32]
  • Hansen JM [27]
  • Albanese S [10]
  • Borrelli K [10]
  • Dimaio F [10]
  • Dimattia MA [10]
  • Farrell DP [10]
  • Guo CJ [10]
  • Horowitz A [10]
  • Kaila N [10]
  • Kennedy MA [10]
  • Kreutter KD [10]
  • Liu JL [10]
  • Mcelwee JJ [10]
  • Quispe J [10]
  • Quispe JD [10]
  • Toms AV [10]
  • Verras A [10]
  • Van Zundert Gcp [10]
  • Dimattia MA [8]
  • Zhong J [8]
  • Baldwin EP [7]
  • Barry RM [7]
  • Gitai Z [7]
  • Chang CC [6]
  • Endrizzi JA [6]
  • Hicks DR [6]
  • Hu HH [6]
  • Maker A [6]
  • Shepherd M [6]
  • Zhou X [6]
  • Lu GM [4]
  • Xian Z [3]
  • Guo SY [2]
  • Ji-long L [2]
  • Kollman J [2]
  • Liu D [2]
  • Lu JL [2]
  • Lynch E [2]
  • Sun Q [2]
  • Wu YF [2]
  • Zhang Z [2]
  • Zhou S [2]
  • Bao X [1]
  • Bao XJ [1]
  • Bitbol A-F [1]
  • Charles EJ [1]
  • Guo C [1]
  • Habrian CH [1]
  • Ji-long L [1]
  • Li H-J [1]
  • Lorestani A [1]
  • Wang Z [1]
  • Wingreen NS [1]

Author by ORCID

  • Lynch EM [28]
  • Hansen JM [27]
  • Kollman JM [12]
  • Quispe J [10]
  • Quispe JD [10]
  • Dimaio F [10]
  • Borrelli K [10]
  • Albanese S [10]
  • Baldwin EP [7]
  • Barry RM [7]
  • Guo CJ [6]
  • Chang CC [6]
  • Maker A [6]
  • Liu JL [6]
  • Hu HH [6]
  • Zhong J [4]
  • Zhou X [4]
  • Lu GM [4]
  • Guo C [1]
  • Wingreen NS [1]
  • Li H-J [1]
  • Bitbol A-F [1]
  • Wang Z [1]

Journal

  • PNAS [14]
  • ELIFE [11]
  • NAT STRUCT MOL BIOL [8]
  • TO BE PUBLISHED [4]
  • J GENET GENOMICS [2]
  • J MOL BIOL [2]
  • CELL BIOSCI [1]
  • MLIFE [1]

Software

  • RELION [18]
  • CRYOSPARC [5]
  • SPIDER [5]
  • HSEARCH_LORENTZ [4]
  • CTFFIND [3]
  • CISTEM [2]
  • CHIMERA [1]
  • SPIDER, HSEARCH_LORENTZ, EMAN1, CTFFIND [1]
  • UCSF CHIMERA [1]

Microscope

  • FEI TITAN KRIOS [32]
  • FEI TECNAI F20 [5]
  • TFS GLACIOS [2]
  • TFS KRIOS [2]
  • FEI POLARA 300 [1]
  • FEI TALOS ARCTICA [1]

Electron Source

  • FIELD EMISSION GUN [43]

Film or detector model

  • GATAN K2 SUMMIT 4K X 4K [31]
  • GATAN K3 6K X 4K [10]
  • GATAN K3 BIOQUANTUM 6K X 4K [1]
  • GATAN ULTRASCAN 4000 4K X 4K [1]

External links

  • PDB [40]
  • UniProt [40]
  • ChEBI [36]
  • ChEMBL [36]
  • DrugBank [36]
  • AlphaFold DB [31]
  • PDBe-Kb [23]
  • Pfam [23]
  • Gene Ontology [22]
  • InterPro [22]
Sort by: Download
Showing 1 - 10 of 43. Page 1 of 5
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EMD-65191
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3D View
human CTPS1 with 2CTP and DON
Release date: Dec. 24, 2025
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 9vmm
Q-score: 0.479

Guo CJ, Bao X, Liu JL

Cell Biosci (2025) 15 pp. 112-112 [ Pubmed: 40739251 DOI: doi:10.1186/s13578-025-01450-6 ]

EMD-42605
Download Map
3D View
M. tuberculosis CTP synthase filament bound to substrates
Release date: July 2, 2025
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8uv4
Q-score: 0.469

Lynch EM, Kollman JM

To Be Published

EMD-42611
Download Map
3D View
M. tuberculosis CTP synthase tetramer bound to CTP
Release date: July 2, 2025
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8uv8
Q-score: 0.447

Lynch EM, Kollman JM

To Be Published

EMD-42612
Download Map
3D View
M. tuberculosis CTP synthase bound to inhibitor GSK1570606A
Release date: July 2, 2025
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8uv9
Q-score: 0.606

Lynch EM, Kollman JM

To Be Published

EMD-42613
Download Map
3D View
M. tuberculosis CTP synthase bound to inhibitor GSK735826A
Release date: July 2, 2025
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8uva
Q-score: 0.576

Lynch EM, Kollman JM

To Be Published

EMD-61008
Download Map
3D View
dmCTPS tetramer with dATP dUTP dGTP and DON
Release date: Nov. 27, 2024
Resolution: 2.73 Å
EM Method: Single-particle
Fitted PDBs: 9iz1
Q-score: 0.473

Guo CJ, Zhang Z, Lu JL, Zhong J, Wu YF, Guo SY, Liu JL

J Mol Biol (2024) 436 pp. 168750-168750 [ DOI: doi:10.1016/j.jmb.2024.168750 Pubmed: 39173734 ]

EMD-61009
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3D View
Focus refinement dmCTPS bound with dATP dUTP dGTP and DON
Release date: Nov. 27, 2024
Resolution: 2.79 Å
EM Method: Single-particle
Fitted PDBs: 9iz2
Q-score: 0.527

Guo CJ, Zhang Z, Lu JL, Zhong J, Wu YF, Guo SY, Liu JL

J Mol Biol (2024) 436 pp. 168750-168750 [ DOI: doi:10.1016/j.jmb.2024.168750 Pubmed: 39173734 ]

EMD-35278
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3D View
ecCTPS filament bound with CTP, NADH, DON
Release date: Feb. 14, 2024
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8i9o
Q-score: 0.514

Guo C, Wang Z, Liu JL

Mlife (2024) 3 pp. 240-250 [ Pubmed: 38948148 DOI: doi:10.1002/mlf2.12119 ]

EMD-32541
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3D View
Structural basis for ligand binding modes of CTP synthase
Release date: Jan. 11, 2023
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7wiz
Q-score: 0.537

Zhou X, Guo CJ, Chang CC, Zhong J, Hu HH, Lu GM, Liu JL

PNAS (2021) 118 [ DOI: doi:10.1073/pnas.2026621118 Pubmed: 34301892 ]

EMD-32542
Download Map
3D View
Structural basis for ligand binding modes of CTP synthase
Release date: Jan. 11, 2023
Resolution: 3.15 Å
EM Method: Single-particle
Fitted PDBs: 7wj4
Q-score: 0.517

Zhou X, Guo CJ, Chang CC, Zhong J, Hu HH, Lu GM, Liu JL

PNAS (2021) 118 [ DOI: doi:10.1073/pnas.2026621118 Pubmed: 34301892 ]

Sort by: Download
Showing 1 - 10 of 43. Page 1 of 5
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [43]

Current status

  • REL [43]

Sample type

  • Protein [41]
  • Complex [36]
  • Ligand [36]
  • Cellular component [6]
  • Sample [1]

Organism

  • Homo sapiens [11]
  • Saccharomyces cerevisiae [10]
  • Drosophila melanogaster [8]
  • Escherichia coli [6]
  • Mycobacterium tuberculosis [4]
  • Mus musculus [3]
  • Escherichia coli [1]

EM Method

  • Single-particle [36]
  • Helical reconstruction [7]

Resolution

  • ≥ 2Å and < 3Å [17]
  • ≥ 3Å and < 4Å [12]
  • ≥ 4Å and < 5Å [1]
  • ≥ 5Å and < 6Å [1]
  • ≥ 6Å and < 8Å [9]
  • ≥ 8Å and < 12Å [3]

Model molecular weight

  • 100-250 kDa [3]
  • 250-500 kDa [22]
  • 500-1000 kDa [8]
  • 1-2 MDa [7]

Release Date

  • 2025 [5]
  • 2024 [3]
  • 2023 [2]
  • 2021 [22]
  • 2020 [2]
  • 2019 [2]
  • 2017 [6]
  • 2014 [1]

Author by name

  • Kollman JM [33]
  • Lynch EM [32]
  • Hansen JM [27]
  • Albanese S [10]
  • Borrelli K [10]
  • Dimaio F [10]
  • Dimattia MA [10]
  • Farrell DP [10]
  • Guo CJ [10]
  • Horowitz A [10]
  • Kaila N [10]
  • Kennedy MA [10]
  • Kreutter KD [10]
  • Liu JL [10]
  • Mcelwee JJ [10]
  • Quispe J [10]
  • Quispe JD [10]
  • Toms AV [10]
  • Verras A [10]
  • Van Zundert Gcp [10]
  • Dimattia MA [8]
  • Zhong J [8]
  • Baldwin EP [7]
  • Barry RM [7]
  • Gitai Z [7]
  • Chang CC [6]
  • Endrizzi JA [6]
  • Hicks DR [6]
  • Hu HH [6]
  • Maker A [6]
  • Shepherd M [6]
  • Zhou X [6]
  • Lu GM [4]
  • Xian Z [3]
  • Guo SY [2]
  • Ji-long L [2]
  • Kollman J [2]
  • Liu D [2]
  • Lu JL [2]
  • Lynch E [2]
  • Sun Q [2]
  • Wu YF [2]
  • Zhang Z [2]
  • Zhou S [2]
  • Bao X [1]
  • Bao XJ [1]
  • Bitbol A-F [1]
  • Charles EJ [1]
  • Guo C [1]
  • Habrian CH [1]
  • Ji-long L [1]
  • Li H-J [1]
  • Lorestani A [1]
  • Wang Z [1]
  • Wingreen NS [1]

Author by ORCID

  • Lynch EM [28]
  • Hansen JM [27]
  • Kollman JM [12]
  • Quispe J [10]
  • Quispe JD [10]
  • Dimaio F [10]
  • Borrelli K [10]
  • Albanese S [10]
  • Baldwin EP [7]
  • Barry RM [7]
  • Guo CJ [6]
  • Chang CC [6]
  • Maker A [6]
  • Liu JL [6]
  • Hu HH [6]
  • Zhong J [4]
  • Zhou X [4]
  • Lu GM [4]
  • Guo C [1]
  • Wingreen NS [1]
  • Li H-J [1]
  • Bitbol A-F [1]
  • Wang Z [1]

Journal

  • PNAS [14]
  • ELIFE [11]
  • NAT STRUCT MOL BIOL [8]
  • TO BE PUBLISHED [4]
  • J GENET GENOMICS [2]
  • J MOL BIOL [2]
  • CELL BIOSCI [1]
  • MLIFE [1]

Software

  • RELION [18]
  • CRYOSPARC [5]
  • SPIDER [5]
  • HSEARCH_LORENTZ [4]
  • CTFFIND [3]
  • CISTEM [2]
  • CHIMERA [1]
  • SPIDER, HSEARCH_LORENTZ, EMAN1, CTFFIND [1]
  • UCSF CHIMERA [1]

Microscope

  • FEI TITAN KRIOS [32]
  • FEI TECNAI F20 [5]
  • TFS GLACIOS [2]
  • TFS KRIOS [2]
  • FEI POLARA 300 [1]
  • FEI TALOS ARCTICA [1]

Electron Source

  • FIELD EMISSION GUN [43]

Film or detector model

  • GATAN K2 SUMMIT 4K X 4K [31]
  • GATAN K3 6K X 4K [10]
  • GATAN K3 BIOQUANTUM 6K X 4K [1]
  • GATAN ULTRASCAN 4000 4K X 4K [1]

External links

  • PDB [40]
  • UniProt [40]
  • ChEBI [36]
  • ChEMBL [36]
  • DrugBank [36]
  • AlphaFold DB [31]
  • PDBe-Kb [23]
  • Pfam [23]
  • Gene Ontology [22]
  • InterPro [22]