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natural_source_ncbi_code:"88776"

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Current Database

  • EMDB [25]

Current status

  • REL [25]

Sample type

  • Complex [25]
  • Protein [25]
  • RNA [23]
  • Ligand [1]

Organism

  • Influenza a virus [25]
  • Camelidae mixed library [17]
  • Staphylococcus aureus [14]
  • Synthetic construct [8]
  • Homo sapiens [4]

EM Method

  • Single-particle [25]

Resolution

  • ≥ 2Å and < 3Å [3]
  • ≥ 3Å and < 4Å [4]
  • ≥ 4Å and < 5Å [9]
  • ≥ 5Å and < 6Å [6]
  • ≥ 6Å and < 8Å [3]

Model molecular weight

  • 250-500 kDa [25]

Release Date

  • 2024 [2]
  • 2023 [2]
  • 2021 [21]

Author by name

  • Carrique L [23]
  • Fodor E [23]
  • Grimes JM [23]
  • Keown JR [23]
  • Fan H [21]
  • Pardon E [21]
  • Serna Martin I [21]
  • Steyaert J [21]
  • Walker AP [21]
  • Zhu Z [21]
  • Alsoussi WB [2]
  • Baazaoui A [2]
  • Choreno-parra JA [2]
  • Cox RJ [2]
  • Cruz-lagunas A [2]
  • Ellebedy AH [2]
  • Hansen L [2]
  • Jimenez-alvarez L [2]
  • Keown J [2]
  • Krammer F [2]
  • Mcmahon M [2]
  • Mudd PA [2]
  • Ozorowski G [2]
  • Rizk AA [2]
  • Schmitz AJ [2]
  • Sebesta M [2]
  • Stadlbauer D [2]
  • Stefl R [2]
  • Strohmeier S [2]
  • Turner HL [2]
  • Turner JS [2]
  • Vahokoski J [2]
  • Ward AB [2]
  • Wilson IA [2]
  • Yu W [2]
  • Zhu X [2]
  • Zuniga J [2]

Author by ORCID

  • Fodor E [23]
  • Zhu Z [21]
  • Pardon E [21]
  • Steyaert J [21]
  • Walker AP [21]
  • Keown JR [21]
  • Fan H [21]
  • Sebesta M [2]
  • Grimes JM [2]
  • Keown J [2]
  • Baazaoui A [2]

Journal

  • NAT COMMUN [21]
  • IMMUNITY [2]
  • J VIROL [2]

Software

  • CRYOSPARC [23]

Microscope

  • FEI TITAN KRIOS [11]
  • TFS GLACIOS [8]
  • TFS KRIOS [6]

Electron Source

  • FIELD EMISSION GUN [25]

Film or detector model

  • FEI FALCON III 4K X 4K [16]
  • GATAN K2 SUMMIT 4K X 4K [7]
  • FEI FALCON IV 4K X 4K [2]

External links

  • Gene Ontology [25]
  • InterPro [25]
  • PDB [25]
  • PDBe-Kb [25]
  • Pfam [25]
  • UniProt [25]
  • AlphaFold DB [16]
  • ChEBI [1]
  • ChEMBL [1]
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EMD-18945
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1918 H1N1 Viral polymerase heterotrimer in complex with 4 repeat serine-5 phosphorylated PolII peptide
Release date: March 27, 2024
Resolution: 3.23 Å
EM Method: Single-particle
Fitted PDBs: 8r60
Q-score: 0.406

Keown J, Baazaoui A, Sebesta M, Stefl R, Carrique L, Fodor E, Grimes JM

J Virol (2024) 98 pp. e0013824-e0013824 [ Pubmed: 38563748 DOI: doi:10.1128/jvi.00138-24 ]

EMD-18947
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1918 H1N1 Viral polymerase heterotrimer in complex with 4 repeat serine-5 phosphorylated PolII peptide with ordered PB2 C-terminal domains
Release date: March 27, 2024
Resolution: 4.23 Å
EM Method: Single-particle
Fitted PDBs: 8r65
Q-score: 0.18

Keown J, Baazaoui A, Sebesta M, Stefl R, Carrique L, Fodor E, Grimes JM

J Virol (2024) 98 pp. e0013824-e0013824 [ Pubmed: 38563748 DOI: doi:10.1128/jvi.00138-24 ]

EMD-27920
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3H03 Fab in complex with influenza virus neuraminidase from A/Brevig Mission/1/1918 H1N1
Release date: Aug. 9, 2023
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 8e6j
Q-score: 0.556

Hansen L, McMahon M, Turner HL, Zhu X, Turner JS, Ozorowski G, Stadlbauer D, Vahokoski J, Schmitz AJ, Rizk AA, Alsoussi WB, Strohmeier S, Yu W, Choreno-Parra JA, Jimenez-Alvarez L, Cruz-Lagunas A, Zuniga J, Mudd PA, Cox RJ, Wilson IA, Ward AB, Ellebedy AH, Krammer F

Immunity (2023) 56 pp. 1927-1938.e8 [ Pubmed: 37506693 DOI: doi:10.1016/j.immuni.2023.07.004 ]

EMD-27921
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2H08 Fab in complex with influenza virus neuraminidase from A/Brevig Mission/1/1918 H1N1
Release date: Aug. 9, 2023
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8e6k
Q-score: 0.512

Hansen L, McMahon M, Turner HL, Zhu X, Turner JS, Ozorowski G, Stadlbauer D, Vahokoski J, Schmitz AJ, Rizk AA, Alsoussi WB, Strohmeier S, Yu W, Choreno-Parra JA, Jimenez-Alvarez L, Cruz-Lagunas A, Zuniga J, Mudd PA, Cox RJ, Wilson IA, Ward AB, Ellebedy AH, Krammer F

Immunity (2023) 56 pp. 1927-1938.e8 [ Pubmed: 37506693 DOI: doi:10.1016/j.immuni.2023.07.004 ]

EMD-12322
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1918 H1N1 Viral influenza polymerase heterotrimer - Endonuclease and priming loop ordered Class2a
Release date: Dec. 1, 2021
Resolution: 2.91 Å
EM Method: Single-particle
Fitted PDBs: 7nha
Q-score: 0.475

Keown JR, Zhu Z, Carrique L, Fan H, Walker AP, Serna Martin I, Pardon E, Steyaert J, Fodor E, Grimes JM

Nat Commun (2022) 13 pp. 251-251 [ DOI: doi:10.1038/s41467-021-27950-w Pubmed: 35017564 ]

EMD-12323
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1918 H1N1 Viral influenza polymerase heterotrimer - Endonuclease ordered Class2b
Release date: Dec. 1, 2021
Resolution: 2.87 Å
EM Method: Single-particle
Fitted PDBs: 7nhc
Q-score: 0.553

Keown JR, Zhu Z, Carrique L, Fan H, Walker AP, Serna Martin I, Pardon E, Steyaert J, Fodor E, Grimes JM

Nat Commun (2022) 13 pp. 251-251 [ DOI: doi:10.1038/s41467-021-27950-w Pubmed: 35017564 ]

EMD-12342
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1918 H1N1 Viral influenza polymerase heterotrimer - full transcriptase Class1
Release date: Dec. 1, 2021
Resolution: 3.23 Å
EM Method: Single-particle
Fitted PDBs: 7nhx
Q-score: 0.406

Keown JR, Zhu Z, Carrique L, Fan H, Walker AP, Serna Martin I, Pardon E, Steyaert J, Fodor E, Grimes JM

Nat Commun (2022) 13 pp. 251-251 [ DOI: doi:10.1038/s41467-021-27950-w Pubmed: 35017564 ]

EMD-12348
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1918 H1N1 Viral influenza polymerase heterotrimer - Replicase class 3
Release date: Dec. 1, 2021
Resolution: 3.32 Å
EM Method: Single-particle
Fitted PDBs: 7ni0
Q-score: 0.385

Keown JR, Zhu Z, Carrique L, Fan H, Walker AP, Serna Martin I, Pardon E, Steyaert J, Fodor E, Grimes JM

Nat Commun (2022) 13 pp. 251-251 [ DOI: doi:10.1038/s41467-021-27950-w Pubmed: 35017564 ]

EMD-12361
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1918 H1N1 Viral influenza polymerase heterotrimer with Nb8189 core
Release date: Dec. 1, 2021
Resolution: 6.2 Å
EM Method: Single-particle
Fitted PDBs: 7nik
Q-score: 0.103

Keown JR, Zhu Z, Carrique L, Fan H, Walker AP, Serna Martin I, Pardon E, Steyaert J, Fodor E, Grimes JM

Nat Commun (2022) 13 pp. 251-251 [ DOI: doi:10.1038/s41467-021-27950-w Pubmed: 35017564 ]

EMD-12362
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1918 H1N1 Viral influenza polymerase heterotrimer with Nb8190 core
Release date: Dec. 1, 2021
Resolution: 5.01 Å
EM Method: Single-particle
Fitted PDBs: 7nil
Q-score: 0.137

Keown JR, Zhu Z, Carrique L, Fan H, Walker AP, Serna Martin I, Pardon E, Steyaert J, Fodor E, Grimes JM

Nat Commun (2022) 13 pp. 251-251 [ DOI: doi:10.1038/s41467-021-27950-w Pubmed: 35017564 ]

Sort by: Download
Showing 1 - 10 of 25. Page 1 of 3
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [25]

Current status

  • REL [25]

Sample type

  • Complex [25]
  • Protein [25]
  • RNA [23]
  • Ligand [1]

Organism

  • Influenza a virus [25]
  • Camelidae mixed library [17]
  • Staphylococcus aureus [14]
  • Synthetic construct [8]
  • Homo sapiens [4]

EM Method

  • Single-particle [25]

Resolution

  • ≥ 2Å and < 3Å [3]
  • ≥ 3Å and < 4Å [4]
  • ≥ 4Å and < 5Å [9]
  • ≥ 5Å and < 6Å [6]
  • ≥ 6Å and < 8Å [3]

Model molecular weight

  • 250-500 kDa [25]

Release Date

  • 2024 [2]
  • 2023 [2]
  • 2021 [21]

Author by name

  • Carrique L [23]
  • Fodor E [23]
  • Grimes JM [23]
  • Keown JR [23]
  • Fan H [21]
  • Pardon E [21]
  • Serna Martin I [21]
  • Steyaert J [21]
  • Walker AP [21]
  • Zhu Z [21]
  • Alsoussi WB [2]
  • Baazaoui A [2]
  • Choreno-parra JA [2]
  • Cox RJ [2]
  • Cruz-lagunas A [2]
  • Ellebedy AH [2]
  • Hansen L [2]
  • Jimenez-alvarez L [2]
  • Keown J [2]
  • Krammer F [2]
  • Mcmahon M [2]
  • Mudd PA [2]
  • Ozorowski G [2]
  • Rizk AA [2]
  • Schmitz AJ [2]
  • Sebesta M [2]
  • Stadlbauer D [2]
  • Stefl R [2]
  • Strohmeier S [2]
  • Turner HL [2]
  • Turner JS [2]
  • Vahokoski J [2]
  • Ward AB [2]
  • Wilson IA [2]
  • Yu W [2]
  • Zhu X [2]
  • Zuniga J [2]

Author by ORCID

  • Fodor E [23]
  • Zhu Z [21]
  • Pardon E [21]
  • Steyaert J [21]
  • Walker AP [21]
  • Keown JR [21]
  • Fan H [21]
  • Sebesta M [2]
  • Grimes JM [2]
  • Keown J [2]
  • Baazaoui A [2]

Journal

  • NAT COMMUN [21]
  • IMMUNITY [2]
  • J VIROL [2]

Software

  • CRYOSPARC [23]

Microscope

  • FEI TITAN KRIOS [11]
  • TFS GLACIOS [8]
  • TFS KRIOS [6]

Electron Source

  • FIELD EMISSION GUN [25]

Film or detector model

  • FEI FALCON III 4K X 4K [16]
  • GATAN K2 SUMMIT 4K X 4K [7]
  • FEI FALCON IV 4K X 4K [2]

External links

  • Gene Ontology [25]
  • InterPro [25]
  • PDB [25]
  • PDBe-Kb [25]
  • Pfam [25]
  • UniProt [25]
  • AlphaFold DB [16]
  • ChEBI [1]
  • ChEMBL [1]