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natural_source_ncbi_code:"371094"

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Current Database

  • EMDB [19]

Current status

  • REL [19]

Sample type

  • Complex [18]
  • Protein [18]
  • Ligand [17]
  • RNA [2]
  • Virus [1]

Organism

  • Chikungunya virus [19]
  • Onyong-nyong virus [1]
  • Baculovirus expression vector pfastbac1-hm [1]
  • Synthetic construct [1]
  • In vitro transcription vector pt7-tp(deltai) [1]

EM Method

  • Single-particle [15]
  • Helical reconstruction [3]
  • Subtomogram averaging [1]

Resolution

  • ≥ 2Å and < 3Å [16]
  • ≥ 3Å and < 4Å [1]
  • ≥ 6Å and < 8Å [1]
  • ≥ 20Å and < 30Å [1]

Model molecular weight

  • 100-250 kDa [1]
  • 250-500 kDa [1]
  • 500-1000 kDa [12]
  • 1-2 MDa [2]
  • 2-5 MDa [1]

Release Date

  • 2024 [3]
  • 2023 [6]
  • 2022 [7]
  • 2021 [1]
  • 2020 [2]

Author by name

  • Jones R [10]
  • Reguera J [10]
  • Hons M [8]
  • Arranz R [7]
  • Law MCY [7]
  • Luo D [7]
  • Tan YB [7]
  • Zhang K [7]
  • Law YS [6]
  • Wirawan M [6]
  • Nguyen TM [5]
  • Rabah N [5]
  • Zamarreno N [5]
  • Jeong LS [4]
  • Amadori C [3]
  • Amara A [3]
  • Bouery Y [3]
  • Burlaud-gaillard J [3]
  • Couture L [3]
  • Desfosses A [3]
  • Karpov A [3]
  • Kril V [3]
  • Kummerer BM [3]
  • Meertens L [3]
  • Ptchelkine D [3]
  • Roingeard P [3]
  • Thienel AL [3]
  • Zimberger C [3]
  • Blijleven JS [2]
  • Bragagnolo G [2]
  • Lee KK [2]
  • Mangala Prasad V [2]
  • Smit JM [2]
  • Chen M [1]
  • Chmielewski D [1]
  • He Y [1]
  • Jin J [1]
  • Luo DH [1]

Author by ORCID

  • Jones R [10]
  • Reguera J [10]
  • Hons M [8]
  • Arranz R [7]
  • Rabah N [5]
  • Zamarreno N [5]
  • Roingeard P [3]
  • Amara A [3]
  • Zimberger C [3]
  • Kril V [3]
  • Desfosses A [3]
  • Kummerer BM [3]
  • Meertens L [3]
  • Thienel AL [3]
  • Lee KK [2]
  • Luo D [2]
  • Blijleven JS [2]
  • Law MCY [2]
  • Tan YB [1]
  • Chmielewski D [1]
  • Chen M [1]
  • Zhang K [1]
  • He Y [1]
  • Jin J [1]

Journal

  • NAT COMMUN [5]
  • PNAS [5]
  • CELL REP [4]
  • NATURE [2]
  • CELL HOST MICROBE [1]
  • J BIOL CHEM [1]
  • SCI ADV [1]

Software

  • RELION [7]
  • CRYOSPARC [4]
  • CTFFIND [1]
  • PEET [1]

Microscope

  • FEI TITAN KRIOS [18]
  • TFS TALOS [1]

Electron Source

  • FIELD EMISSION GUN [19]

Film or detector model

  • GATAN K2 SUMMIT 4K X 4K [12]
  • GATAN K3 6K X 4K [3]
  • GATAN K3 BIOQUANTUM 6K X 4K [3]
  • FEI FALCON III 4K X 4K [1]

External links

  • ChEBI [17]
  • ChEMBL [17]
  • DrugBank [17]
  • InterPro [17]
  • PDB [17]
  • PDBe-Kb [17]
  • Pfam [17]
  • UniProt [17]
  • Gene Ontology [15]
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Showing 1 - 10 of 19. Page 1 of 2
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EMD-17678
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3D View
Helical reconstruction of CHIKV nsP3 helical scaffolds
Release date: Aug. 14, 2024
Resolution: 2.35 Å
EM Method: Helical reconstruction
Fitted PDBs: 8phz

Kril V, Hons M, Amadori C, Zimberger C, Couture L, Bouery Y, Burlaud-Gaillard J, Karpov A, Ptchelkine D, Thienel AL, Kummerer BM, Desfosses A, Jones R, Roingeard P, Meertens L, Amara A, Reguera J

Nat Commun (2024) 15 pp. 8106-8106 [ Pubmed: 39285216 DOI: doi:10.1038/s41467-024-51952-z ]

EMD-17729
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Helical reconstruction of CHIKV nsP3 helical scaffolds
Release date: Aug. 14, 2024
Resolution: 2.52 Å
EM Method: Helical reconstruction
Fitted PDBs: 8pk7

Kril V, Hons M, Amadori C, Zimberger C, Couture L, Bouery Y, Burlaud-Gaillard J, Karpov A, Ptchelkine D, Thienel AL, Kummerer BM, Desfosses A, Jones R, Roingeard P, Meertens L, Amara A, Reguera J

Nat Commun (2024) 15 pp. 8106-8106 [ Pubmed: 39285216 DOI: doi:10.1038/s41467-024-51952-z ]

EMD-17730
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masked refinement giving rise to better defined protruding densities of the potential macrodomain outside the AUD helical assemblies.
Release date: July 10, 2024
Resolution: 2.98 Å
EM Method: Helical reconstruction

Kril V, Hons M, Amadori C, Zimberger C, Couture L, Bouery Y, Burlaud-Gaillard J, Karpov A, Ptchelkine D, Thienel AL, Kummerer BM, Desfosses A, Jones R, Roingeard P, Meertens L, Amara A, Reguera J

Nat Commun (2024) 15 pp. 8106-8106 [ Pubmed: 39285216 DOI: doi:10.1038/s41467-024-51952-z ]

EMD-36159
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Cryo-EM Structure of Chikungunya Virus Nonstructural Protein 1 with m7GpppAmU
Release date: Nov. 15, 2023
Resolution: 2.41 Å
EM Method: Single-particle
Fitted PDBs: 8jce
Q-score: 0.643

Law MCY, Zhang K, Tan YB, Nguyen TM, Luo D

J Biol Chem (2023) 299 pp. 105415-105415 [ Pubmed: 37918803 DOI: doi:10.1016/j.jbc.2023.105415 ]

EMD-15553
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CryoEM structure of the Chikungunya virus nsP1 capping pores in complex with GTP
Release date: May 31, 2023
Resolution: 2.48 Å
EM Method: Single-particle
Fitted PDBs: 8aov
Q-score: 0.616

Jones R, Hons M, Rabah N, Zamarreno N, Arranz R, Reguera J

PNAS (2023) 120 pp. e2213934120-e2213934120 [ DOI: doi:10.1073/pnas.2213934120 Pubmed: 36913573 ]

EMD-15578
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CryoEM structure of the Chikungunya virus nsP1 capping pores in covalent complex with a 7GMP cap structure
Release date: May 3, 2023
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8apx
Q-score: 0.391

Jones R, Hons M, Rabah N, Zamarreno N, Arranz R, Reguera J

PNAS (2023) 120 pp. e2213934120-e2213934120 [ DOI: doi:10.1073/pnas.2213934120 Pubmed: 36913573 ]

EMD-15554
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CryoEM structure of the Chikungunya virus nsP1 capping pores in complex with m7GTP and SAH ligands
Release date: March 29, 2023
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 8aow
Q-score: 0.584

Jones R, Hons M, Rabah N, Zamarreno N, Arranz R, Reguera J

PNAS (2023) 120 pp. e2213934120-e2213934120 [ DOI: doi:10.1073/pnas.2213934120 Pubmed: 36913573 ]

EMD-15555
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3D View
CryoEM structure of the Chikungunya virus nsP1 capping pores in complex with SAM
Release date: March 29, 2023
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8aox
Q-score: 0.574

Jones R, Hons M, Rabah N, Zamarreno N, Arranz R, Reguera J

PNAS (2023) 120 pp. e2213934120-e2213934120 [ DOI: doi:10.1073/pnas.2213934120 Pubmed: 36913573 ]

EMD-15704
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Structure of an open form of CHIKV nsP1 capping pores
Release date: March 29, 2023
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8axv
Q-score: 0.47

Jones R, Hons M, Rabah N, Zamarreno N, Arranz R, Reguera J

PNAS (2023) 120 pp. e2213934120-e2213934120 [ DOI: doi:10.1073/pnas.2213934120 Pubmed: 36913573 ]

EMD-33591
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Molecular architecture of the chikungunya virus replication complex
Release date: Dec. 14, 2022
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7y38
Q-score: 0.539

Tan YB, Chmielewski D, Law MCY, Zhang K, He Y, Chen M, Jin J, Luo D

Sci Adv (2022) 8 pp. eadd2536-eadd2536 [ Pubmed: 36449616 DOI: doi:10.1126/sciadv.add2536 ]

Sort by: Download
Showing 1 - 10 of 19. Page 1 of 2
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [19]

Current status

  • REL [19]

Sample type

  • Complex [18]
  • Protein [18]
  • Ligand [17]
  • RNA [2]
  • Virus [1]

Organism

  • Chikungunya virus [19]
  • Onyong-nyong virus [1]
  • Baculovirus expression vector pfastbac1-hm [1]
  • Synthetic construct [1]
  • In vitro transcription vector pt7-tp(deltai) [1]

EM Method

  • Single-particle [15]
  • Helical reconstruction [3]
  • Subtomogram averaging [1]

Resolution

  • ≥ 2Å and < 3Å [16]
  • ≥ 3Å and < 4Å [1]
  • ≥ 6Å and < 8Å [1]
  • ≥ 20Å and < 30Å [1]

Model molecular weight

  • 100-250 kDa [1]
  • 250-500 kDa [1]
  • 500-1000 kDa [12]
  • 1-2 MDa [2]
  • 2-5 MDa [1]

Release Date

  • 2024 [3]
  • 2023 [6]
  • 2022 [7]
  • 2021 [1]
  • 2020 [2]

Author by name

  • Jones R [10]
  • Reguera J [10]
  • Hons M [8]
  • Arranz R [7]
  • Law MCY [7]
  • Luo D [7]
  • Tan YB [7]
  • Zhang K [7]
  • Law YS [6]
  • Wirawan M [6]
  • Nguyen TM [5]
  • Rabah N [5]
  • Zamarreno N [5]
  • Jeong LS [4]
  • Amadori C [3]
  • Amara A [3]
  • Bouery Y [3]
  • Burlaud-gaillard J [3]
  • Couture L [3]
  • Desfosses A [3]
  • Karpov A [3]
  • Kril V [3]
  • Kummerer BM [3]
  • Meertens L [3]
  • Ptchelkine D [3]
  • Roingeard P [3]
  • Thienel AL [3]
  • Zimberger C [3]
  • Blijleven JS [2]
  • Bragagnolo G [2]
  • Lee KK [2]
  • Mangala Prasad V [2]
  • Smit JM [2]
  • Chen M [1]
  • Chmielewski D [1]
  • He Y [1]
  • Jin J [1]
  • Luo DH [1]

Author by ORCID

  • Jones R [10]
  • Reguera J [10]
  • Hons M [8]
  • Arranz R [7]
  • Rabah N [5]
  • Zamarreno N [5]
  • Roingeard P [3]
  • Amara A [3]
  • Zimberger C [3]
  • Kril V [3]
  • Desfosses A [3]
  • Kummerer BM [3]
  • Meertens L [3]
  • Thienel AL [3]
  • Lee KK [2]
  • Luo D [2]
  • Blijleven JS [2]
  • Law MCY [2]
  • Tan YB [1]
  • Chmielewski D [1]
  • Chen M [1]
  • Zhang K [1]
  • He Y [1]
  • Jin J [1]

Journal

  • NAT COMMUN [5]
  • PNAS [5]
  • CELL REP [4]
  • NATURE [2]
  • CELL HOST MICROBE [1]
  • J BIOL CHEM [1]
  • SCI ADV [1]

Software

  • RELION [7]
  • CRYOSPARC [4]
  • CTFFIND [1]
  • PEET [1]

Microscope

  • FEI TITAN KRIOS [18]
  • TFS TALOS [1]

Electron Source

  • FIELD EMISSION GUN [19]

Film or detector model

  • GATAN K2 SUMMIT 4K X 4K [12]
  • GATAN K3 6K X 4K [3]
  • GATAN K3 BIOQUANTUM 6K X 4K [3]
  • FEI FALCON III 4K X 4K [1]

External links

  • ChEBI [17]
  • ChEMBL [17]
  • DrugBank [17]
  • InterPro [17]
  • PDB [17]
  • PDBe-Kb [17]
  • Pfam [17]
  • UniProt [17]
  • Gene Ontology [15]