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grant_code:"R35GM141262"

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Current Database

  • EMDB [4]

Current status

  • REL [4]

Sample type

  • Complex [4]
  • Ligand [2]
  • Protein [2]
  • RNA [2]

Organism

  • Caenorhabditis elegans [3]
  • Synthetic construct [2]

EM Method

  • Single-particle [4]

Resolution

  • ≥ 2Å and < 3Å [1]
  • ≥ 3Å and < 4Å [1]
  • ≥ 6Å and < 8Å [2]

Model molecular weight

  • 50-100 kDa [1]
  • 100-250 kDa [1]

Release Date

  • 2025 [1]
  • 2024 [3]

Author by name

  • Aderounmu AM [4]
  • Bass BL [4]
  • Consalvo CD [4]
  • Shen PS [4]
  • Aruscavage PJ [3]
  • Donelick HM [3]
  • Eckert DM [3]
  • Maus-conn J [1]

Author by ORCID

  • Shen PS [4]
  • Bass BL [4]
  • Consalvo CD [4]
  • Aderounmu AM [1]
  • Maus-conn J [1]

Journal

  • ELIFE [3]
  • BIORXIV [1]
  • PNAS [1]

Software

  • CRYOSPARC [1]

Microscope

  • FEI TITAN KRIOS [3]
  • TFS KRIOS [1]

Electron Source

  • FIELD EMISSION GUN [4]

Film or detector model

  • GATAN K3 BIOQUANTUM 6K X 4K [4]

External links

  • ChEBI [2]
  • ChEMBL [2]
  • DrugBank [2]
  • PDB [2]
  • AlphaFold DB [1]
  • Gene Ontology [1]
  • InterPro [1]
  • PDBe-Kb [1]
  • Pfam [1]
  • UniProt [1]
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EMD-48691
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3D View
Cryo-EM structure of ancestral Dicer helicase bound to 27-bp dsRNA in end-bound transition state
Release date: March 12, 2025
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 9mw7
Q-score: 0.289

Aderounmu AM, Maus-Conn J, Consalvo CD, Shen PS, Bass BL

PNAS (2025) 122 pp. e2500825122-e2500825122 [ Pubmed: 40434637 DOI: doi:10.1073/pnas.2500825122 ]

EMD-41060
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Cryo-EM structure of DRH-1 helicase and C-terminal domain bound to dsRNA
Release date: May 15, 2024
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8t5s
Q-score: 0.428

Consalvo CD, Aderounmu AM, Donelick HM, Aruscavage PJ, Eckert DM, Shen PS, Bass BL

eLife (2024) 13 [ Pubmed: 38747717 DOI: doi:10.7554/eLife.93979 ]

EMD-43430
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3D View
Cryo-EM structure of C. elegans antiviral complex Dicer-1, DRH-1, and RDE-4 bound to one dsRNA
Release date: May 15, 2024
Resolution: 6.1 Å
EM Method: Single-particle

Consalvo CD, Aderounmu AM, Donelick HM, Aruscavage PJ, Eckert DM, Shen PS, Bass BL

eLife (2024) 13 [ Pubmed: 38747717 DOI: doi:10.7554/eLife.93979 ]

EMD-43431
Download Map
3D View
Cryo-EM structure of C. elegans antiviral complex Dicer-1, DRH-1, and RDE-4 bound to two dsRNA
Release date: May 15, 2024
Resolution: 7.6 Å
EM Method: Single-particle

Consalvo CD, Aderounmu AM, Donelick HM, Aruscavage PJ, Eckert DM, Shen PS, Bass BL

eLife (2024) 13 [ Pubmed: 38747717 DOI: doi:10.7554/eLife.93979 ]

Sort by: Download
Showing 1 - 4 of 4. Page 1 of 1
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [4]

Current status

  • REL [4]

Sample type

  • Complex [4]
  • Ligand [2]
  • Protein [2]
  • RNA [2]

Organism

  • Caenorhabditis elegans [3]
  • Synthetic construct [2]

EM Method

  • Single-particle [4]

Resolution

  • ≥ 2Å and < 3Å [1]
  • ≥ 3Å and < 4Å [1]
  • ≥ 6Å and < 8Å [2]

Model molecular weight

  • 50-100 kDa [1]
  • 100-250 kDa [1]

Release Date

  • 2025 [1]
  • 2024 [3]

Author by name

  • Aderounmu AM [4]
  • Bass BL [4]
  • Consalvo CD [4]
  • Shen PS [4]
  • Aruscavage PJ [3]
  • Donelick HM [3]
  • Eckert DM [3]
  • Maus-conn J [1]

Author by ORCID

  • Shen PS [4]
  • Bass BL [4]
  • Consalvo CD [4]
  • Aderounmu AM [1]
  • Maus-conn J [1]

Journal

  • ELIFE [3]
  • BIORXIV [1]
  • PNAS [1]

Software

  • CRYOSPARC [1]

Microscope

  • FEI TITAN KRIOS [3]
  • TFS KRIOS [1]

Electron Source

  • FIELD EMISSION GUN [4]

Film or detector model

  • GATAN K3 BIOQUANTUM 6K X 4K [4]

External links

  • ChEBI [2]
  • ChEMBL [2]
  • DrugBank [2]
  • PDB [2]
  • AlphaFold DB [1]
  • Gene Ontology [1]
  • InterPro [1]
  • PDBe-Kb [1]
  • Pfam [1]
  • UniProt [1]