Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

Edit your search query here and hit Return to execute it:
grant_code:"R01 GM121964"

Filter By

Current Database

  • EMDB [7]

Current status

  • REL [7]

Sample type

  • Protein [7]
  • Complex [6]
  • Cellular component [1]
  • Ligand [1]

Organism

  • Homo sapiens [5]
  • Mycobacterium tuberculosis [2]

EM Method

  • Single-particle [7]

Resolution

  • ≥ 3Å and < 4Å [4]
  • ≥ 4Å and < 5Å [3]

Model molecular weight

  • 50-100 kDa [2]
  • 100-250 kDa [5]

Release Date

  • 2021 [5]
  • 2020 [2]

Author by name

  • Liang WG [7]
  • Zhao M [7]
  • Mancl JM [6]
  • Tang WJ [6]
  • Carragher B [4]
  • Koehler CM [4]
  • Lee D [4]
  • Li S [4]
  • Lin King Jv [4]
  • Liu C [4]
  • Mo S [4]
  • Noble AJ [4]
  • Pan M [4]
  • Potter CS [4]
  • Wei H [4]
  • Wijaya J [4]
  • Tang W [1]

Author by ORCID

  • Zhao M [4]
  • Wei H [4]
  • Pan M [4]
  • Lee D [4]
  • Noble AJ [4]
  • Liu C [4]
  • Carragher B [4]
  • Tang WJ [4]
  • Li S [4]
  • Mancl JM [2]

Journal

  • NAT COMMUN [4]
  • STRUCTURE [2]
  • TO BE PUBLISHED [1]

Software

  • RELION [7]
  • CTFFIND [6]

Microscope

  • FEI TITAN KRIOS [7]

Electron Source

  • FIELD EMISSION GUN [7]

Film or detector model

  • GATAN K2 SUMMIT 4K X 4K [5]
  • GATAN K3 6K X 4K [2]

External links

  • AlphaFold DB [7]
  • PDB [7]
  • UniProt [7]
  • Gene Ontology [6]
  • InterPro [6]
  • PDBe-Kb [6]
  • Pfam [6]
  • Complex Portal [5]
  • EMPIAR [5]
  • ChEBI [1]
  • ChEMBL [1]
  • DrugBank [1]
Sort by: Download
Showing 1 - 7 of 7. Page 1 of 1
Display:
Statistics
×

Download











































Preview first 10
Download
EMD-22278
Download Map
3D View
Raw data
EMPIAR-10937
CryoEM structure of human presequence protease in partial open state 1
Release date: July 7, 2021
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 6xos
Q-score: 0.405

Liang WG, Wijaya J, Wei H, Noble AJ, Mancl JM, Mo S, Lee D, Lin King JV, Pan M, Liu C, Koehler CM, Zhao M, Potter CS, Carragher B, Li S, Tang WJ

Nat Commun (2022) 13 pp. 1833-1833 [ DOI: doi:10.1038/s41467-022-29322-4 Pubmed: 35383169 ]

EMD-22279
Download Map
3D View
Raw data
EMPIAR-10937
CryoEM structure of human presequence protease in partial open state 2
Release date: July 7, 2021
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 6xot
Q-score: 0.315

Liang WG, Wijaya J, Wei H, Noble AJ, Mancl JM, Mo S, Lee D, Lin King JV, Pan M, Liu C, Koehler CM, Zhao M, Potter CS, Carragher B, Li S, Tang WJ

Nat Commun (2022) 13 pp. 1833-1833 [ DOI: doi:10.1038/s41467-022-29322-4 Pubmed: 35383169 ]

EMD-22280
Download Map
3D View
Raw data
EMPIAR-10937
CryoEM structure of human presequence protease in open state
Release date: July 7, 2021
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 6xou
Q-score: 0.333

Liang WG, Wijaya J, Wei H, Noble AJ, Mancl JM, Mo S, Lee D, Lin King JV, Pan M, Liu C, Koehler CM, Zhao M, Potter CS, Carragher B, Li S, Tang WJ

Nat Commun (2022) 13 pp. 1833-1833 [ DOI: doi:10.1038/s41467-022-29322-4 Pubmed: 35383169 ]

EMD-22281
Download Map
3D View
Raw data
EMPIAR-10937
CryoEM structure of human presequence protease in partial closed state 1
Release date: July 7, 2021
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 6xov
Q-score: 0.468

Liang WG, Wijaya J, Wei H, Noble AJ, Mancl JM, Mo S, Lee D, Lin King JV, Pan M, Liu C, Koehler CM, Zhao M, Potter CS, Carragher B, Li S, Tang WJ

Nat Commun (2022) 13 pp. 1833-1833 [ DOI: doi:10.1038/s41467-022-29322-4 Pubmed: 35383169 ]

EMD-22282
Download Map
3D View
Raw data
EMPIAR-10937
CryoEM structure of human presequence protease in partial close state 2, induced by presequence of citrate synthase
Release date: July 7, 2021
Resolution: 4.6 Å
EM Method: Single-particle
Fitted PDBs: 6xow
Q-score: 0.214

Liang WG, Zhao M, Tang W

To Be Published

EMD-22252
Download Map
3D View
CRYOEM STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS ZINC METALLOPROTEASE ZMP1 IN OPEN STATE
Release date: Dec. 23, 2020
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6xly
Q-score: 0.457

Liang WG, Mancl JM, Zhao M, Tang WJ

Structure (2021) 29 pp. 709- [ DOI: doi:10.1016/j.str.2020.12.002 Pubmed: 33378640 ]

EMD-22630
Download Map
3D View
Partial open state of Mycobacterium tuberculosis zinc metalloprotease 1
Release date: Dec. 23, 2020
Resolution: 4.6 Å
EM Method: Single-particle
Fitted PDBs: 7k1v
Q-score: 0.223

Liang WG, Mancl JM, Zhao M, Tang WJ

Structure (2021) 29 pp. 709- [ DOI: doi:10.1016/j.str.2020.12.002 Pubmed: 33378640 ]

Sort by: Download
Showing 1 - 7 of 7. Page 1 of 1
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [7]

Current status

  • REL [7]

Sample type

  • Protein [7]
  • Complex [6]
  • Cellular component [1]
  • Ligand [1]

Organism

  • Homo sapiens [5]
  • Mycobacterium tuberculosis [2]

EM Method

  • Single-particle [7]

Resolution

  • ≥ 3Å and < 4Å [4]
  • ≥ 4Å and < 5Å [3]

Model molecular weight

  • 50-100 kDa [2]
  • 100-250 kDa [5]

Release Date

  • 2021 [5]
  • 2020 [2]

Author by name

  • Liang WG [7]
  • Zhao M [7]
  • Mancl JM [6]
  • Tang WJ [6]
  • Carragher B [4]
  • Koehler CM [4]
  • Lee D [4]
  • Li S [4]
  • Lin King Jv [4]
  • Liu C [4]
  • Mo S [4]
  • Noble AJ [4]
  • Pan M [4]
  • Potter CS [4]
  • Wei H [4]
  • Wijaya J [4]
  • Tang W [1]

Author by ORCID

  • Zhao M [4]
  • Wei H [4]
  • Pan M [4]
  • Lee D [4]
  • Noble AJ [4]
  • Liu C [4]
  • Carragher B [4]
  • Tang WJ [4]
  • Li S [4]
  • Mancl JM [2]

Journal

  • NAT COMMUN [4]
  • STRUCTURE [2]
  • TO BE PUBLISHED [1]

Software

  • RELION [7]
  • CTFFIND [6]

Microscope

  • FEI TITAN KRIOS [7]

Electron Source

  • FIELD EMISSION GUN [7]

Film or detector model

  • GATAN K2 SUMMIT 4K X 4K [5]
  • GATAN K3 6K X 4K [2]

External links

  • AlphaFold DB [7]
  • PDB [7]
  • UniProt [7]
  • Gene Ontology [6]
  • InterPro [6]
  • PDBe-Kb [6]
  • Pfam [6]
  • Complex Portal [5]
  • EMPIAR [5]
  • ChEBI [1]
  • ChEMBL [1]
  • DrugBank [1]