Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

Edit your search query here and hit Return to execute it:
grant_code:"R01 DK066485-13"

Filter By

Current Database

  • EMDB [7]

Current status

  • REL [7]

Sample type

  • Complex [7]
  • Protein [6]
  • Ligand [3]

Organism

  • Cricetus cricetus [7]
  • Rattus norvegicus [7]

EM Method

  • Single-particle [7]

Resolution

  • ≥ 3Å and < 4Å [2]
  • ≥ 4Å and < 5Å [1]
  • ≥ 5Å and < 6Å [2]
  • ≥ 6Å and < 8Å [1]

Model molecular weight

  • 250-500 kDa [7]

Release Date

  • 2022 [7]

Author by name

  • Driggers CM [7]
  • Mostofian B [7]
  • Patton BL [7]
  • Russo JD [7]
  • Shyng SL [7]
  • Sung MW [7]
  • Zuckerman DM [7]

Author by ORCID

  • Zuckerman DM [7]
  • Driggers CM [7]
  • Russo JD [7]

Journal

  • ELIFE [7]
  • J MOL BIOL [7]

Software

  • RELION [6]

Microscope

  • FEI TITAN KRIOS [7]

Electron Source

  • FIELD EMISSION GUN [7]

Film or detector model

  • GATAN K2 SUMMIT 4K X 4K [6]
  • FEI FALCON III 4K X 4K [1]

External links

  • PDB [7]
  • AlphaFold DB [6]
  • Complex Portal [6]
  • Gene Ontology [6]
  • InterPro [6]
  • PDBe-Kb [6]
  • Pfam [6]
  • UniProt [6]
  • ChEBI [3]
  • ChEMBL [3]
  • DrugBank [3]
Sort by: Download
Showing 1 - 7 of 7. Page 1 of 1
Display:
Statistics
×

Download











































Preview first 10
Download
EMD-26304
Download Map
3D View
Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and repaglinide with SUR1-out conformation
Release date: Aug. 31, 2022
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7u1s
Q-score: 0.404

Sung MW, Driggers CM, Mostofian B, Russo JD, Patton BL, Zuckerman DM, Shyng SL

J Mol Biol (2022) 434 pp. 167789-167789 [ DOI: doi:10.1016/j.jmb.2022.167789 Pubmed: 35964676 ]

EMD-26307
Download Map
3D View
Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and glibenclamide with Kir6.2-CTD in the up conformation
Release date: Aug. 31, 2022
Resolution: 3.58 Å
EM Method: Single-particle
Fitted PDBs: 7u24
Q-score: 0.452

Sung MW, Driggers CM, Mostofian B, Russo JD, Patton BL, Zuckerman DM, Shyng SL

J Mol Biol (2022) 434 pp. 167789-167789 [ DOI: doi:10.1016/j.jmb.2022.167789 Pubmed: 35964676 ]

EMD-26308
Download Map
3D View
Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and glibenclamide with Kir6.2-CTD in the down conformation
Release date: Aug. 31, 2022
Resolution: 6.8 Å
EM Method: Single-particle
Fitted PDBs: 7u6y
Q-score: 0.233

Sung MW, Driggers CM, Mostofian B, Russo JD, Patton BL, Zuckerman DM, Shyng SL

J Mol Biol (2022) 434 pp. 167789-167789 [ DOI: doi:10.1016/j.jmb.2022.167789 Pubmed: 35964676 ]

EMD-26309
Download Map
3D View
Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and in the presence of carbamazepine with Kir6.2-CTD in the up conformation
Release date: Aug. 31, 2022
Resolution: 5.2 Å
EM Method: Single-particle
Fitted PDBs: 7u7m
Q-score: 0.249

Sung MW, Driggers CM, Mostofian B, Russo JD, Patton BL, Zuckerman DM, Shyng SL

J Mol Biol (2022) 434 pp. 167789-167789 [ DOI: doi:10.1016/j.jmb.2022.167789 Pubmed: 35964676 ]

EMD-26312
Download Map
3D View
Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP with Kir6.2-CTD in the up conformation
Release date: Aug. 31, 2022
Resolution: 5.7 Å
EM Method: Single-particle
Fitted PDBs: 7uaa
Q-score: 0.26

Sung MW, Driggers CM, Mostofian B, Russo JD, Patton BL, Zuckerman DM, Shyng SL

J Mol Biol (2022) 434 pp. 167789-167789 [ DOI: doi:10.1016/j.jmb.2022.167789 Pubmed: 35964676 ]

EMD-26320
Download Map
3D View
Cryo-EM structure of the pancreatic ATP-sensitive potassium channel in the apo form with Kir6.2-CTD in the down conformation
Release date: Aug. 31, 2022
EM Method: Single-particle
Fitted PDBs: 7uqr

Sung MW, Driggers CM, Mostofian B, Russo JD, Patton BL, Zuckerman DM, Shyng SL

J Mol Biol (2022) 434 pp. 167789-167789 [ DOI: doi:10.1016/j.jmb.2022.167789 Pubmed: 35964676 ]

EMD-26321
Download Map
3D View
Cryo-EM structure of the pancreatic ATP-sensitive potassium channel in the presence of carbamazepine and ATP with Kir6.2-CTD in the down conformation
Release date: Aug. 31, 2022
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 7u2x
Q-score: 0.389

Sung MW, Driggers CM, Mostofian B, Russo JD, Patton BL, Zuckerman DM, Shyng SL

J Mol Biol (2022) 434 pp. 167789-167789 [ DOI: doi:10.1016/j.jmb.2022.167789 Pubmed: 35964676 ]

Sort by: Download
Showing 1 - 7 of 7. Page 1 of 1
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [7]

Current status

  • REL [7]

Sample type

  • Complex [7]
  • Protein [6]
  • Ligand [3]

Organism

  • Cricetus cricetus [7]
  • Rattus norvegicus [7]

EM Method

  • Single-particle [7]

Resolution

  • ≥ 3Å and < 4Å [2]
  • ≥ 4Å and < 5Å [1]
  • ≥ 5Å and < 6Å [2]
  • ≥ 6Å and < 8Å [1]

Model molecular weight

  • 250-500 kDa [7]

Release Date

  • 2022 [7]

Author by name

  • Driggers CM [7]
  • Mostofian B [7]
  • Patton BL [7]
  • Russo JD [7]
  • Shyng SL [7]
  • Sung MW [7]
  • Zuckerman DM [7]

Author by ORCID

  • Zuckerman DM [7]
  • Driggers CM [7]
  • Russo JD [7]

Journal

  • ELIFE [7]
  • J MOL BIOL [7]

Software

  • RELION [6]

Microscope

  • FEI TITAN KRIOS [7]

Electron Source

  • FIELD EMISSION GUN [7]

Film or detector model

  • GATAN K2 SUMMIT 4K X 4K [6]
  • FEI FALCON III 4K X 4K [1]

External links

  • PDB [7]
  • AlphaFold DB [6]
  • Complex Portal [6]
  • Gene Ontology [6]
  • InterPro [6]
  • PDBe-Kb [6]
  • Pfam [6]
  • UniProt [6]
  • ChEBI [3]
  • ChEMBL [3]
  • DrugBank [3]