Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

Edit your search query here and hit Return to execute it:
grant_code:"GM143282"

Filter By

Current Database

  • EMDB [44]

Current status

  • REL [44]

Sample type

  • Complex [44]
  • Protein [39]
  • Ligand [29]

Organism

  • Homo sapiens [44]
  • Mus musculus [10]

EM Method

  • Single-particle [44]

Resolution

  • ≥ 2Å and < 3Å [15]
  • ≥ 3Å and < 4Å [25]
  • ≥ 4Å and < 5Å [4]

Model molecular weight

  • 0-50 kDa [5]
  • 50-100 kDa [21]
  • 100-250 kDa [12]
  • 250-500 kDa [1]

Release Date

  • 2025 [22]
  • 2024 [10]
  • 2023 [8]
  • 2022 [4]

Author by name

  • Dai Y [44]
  • Lee CH [44]
  • Pidathala S [25]
  • Chen X [22]
  • Niu Y [22]
  • Li S [16]
  • Wang H [16]
  • Wang L [16]
  • Zhao C [16]
  • Zhao H [9]
  • Li X [8]
  • Gorgulla C [6]
  • Liu F [6]
  • Nguyen LN [6]
  • Ahmed S [5]
  • Chen H [5]
  • Elghobashi-meinhardt N [5]
  • Kim JH [5]
  • Mcdonald JG [5]
  • Jan LY [4]
  • Lo YH [4]
  • Wang Y [4]
  • Ye W [4]
  • Chang CL [3]
  • Liao S [3]
  • Long C [3]
  • Zhang Z [3]

Author by ORCID

  • Dai Y [44]
  • Lee CH [35]
  • Pidathala S [22]
  • Zhao C [16]
  • Niu Y [16]
  • Liu F [6]
  • Gorgulla C [6]
  • Nguyen LN [6]
  • Li X [5]
  • Elghobashi-meinhardt N [5]
  • Chen H [5]
  • Ahmed S [5]
  • Ye W [4]
  • Li X [3]
  • Zhang Z [3]
  • Long C [3]
  • Chang CL [3]

Journal

  • CELL RES [26]
  • NAT COMMUN [6]
  • CELL [5]
  • MOL CELL [4]
  • NATURE [3]

Software

  • CRYOSPARC [5]

Microscope

  • FEI TITAN KRIOS [22]
  • TFS KRIOS [22]

Electron Source

  • FIELD EMISSION GUN [44]

Film or detector model

  • GATAN K3 6K X 4K [44]

External links

  • AlphaFold DB [39]
  • PDB [39]
  • UniProt [39]
  • Pfam [34]
  • Complex Portal [28]
  • Gene Ontology [28]
  • PDBe-Kb [28]
  • InterPro [22]
  • ChEBI [19]
  • ChEMBL [15]
  • DrugBank [9]
Sort by: Download
Showing 1 - 10 of 44. Page 1 of 5
Display:
Statistics
×

Download











































Preview first 10
Download
EMD-70562
Download Map
3D View
Cryo-EM structure of human SV2A in the apo state
Release date: Dec. 10, 2025
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 9okf
Q-score: 0.563

Pidathala S, Chen X, Dai Y, Nguyen LN, Gorgulla C, Niu Y, Liu F, Lee CH

Nat Commun (2025) 16 pp. 10748-10748 [ DOI: doi:10.1038/s41467-025-65781-1 Pubmed: 41315229 ]

EMD-70563
Download Map
3D View
Cryo-EM structure of human SV2A in complex with levetiracetam
Release date: Dec. 10, 2025
Resolution: 2.58 Å
EM Method: Single-particle
Fitted PDBs: 9okg
Q-score: 0.607

Pidathala S, Chen X, Dai Y, Nguyen LN, Gorgulla C, Niu Y, Liu F, Lee CH

Nat Commun (2025) 16 pp. 10748-10748 [ DOI: doi:10.1038/s41467-025-65781-1 Pubmed: 41315229 ]

EMD-70564
Download Map
3D View
Cryo-EM structure of human SV2A in complex with UCBJ
Release date: Dec. 10, 2025
Resolution: 2.39 Å
EM Method: Single-particle
Fitted PDBs: 9okh
Q-score: 0.593

Pidathala S, Chen X, Dai Y, Nguyen LN, Gorgulla C, Niu Y, Liu F, Lee CH

Nat Commun (2025) 16 pp. 10748-10748 [ DOI: doi:10.1038/s41467-025-65781-1 Pubmed: 41315229 ]

EMD-70565
Download Map
3D View
Cryo-EM structure of human SV2A in complex with UCBJ and UCB1244283
Release date: Dec. 10, 2025
Resolution: 2.67 Å
EM Method: Single-particle
Fitted PDBs: 9oki
Q-score: 0.599

Pidathala S, Chen X, Dai Y, Nguyen LN, Gorgulla C, Niu Y, Liu F, Lee CH

Nat Commun (2025) 16 pp. 10748-10748 [ DOI: doi:10.1038/s41467-025-65781-1 Pubmed: 41315229 ]

EMD-70566
Download Map
3D View
Cryo-EM structure of human SV2A in complex with padsevonil
Release date: Dec. 10, 2025
Resolution: 2.68 Å
EM Method: Single-particle
Fitted PDBs: 9okj
Q-score: 0.587

Pidathala S, Chen X, Dai Y, Nguyen LN, Gorgulla C, Niu Y, Liu F, Lee CH

Nat Commun (2025) 16 pp. 10748-10748 [ DOI: doi:10.1038/s41467-025-65781-1 Pubmed: 41315229 ]

EMD-71812
Download Map
3D View
Cryo-EM structure of human SV2A in complex with Levetiracetam and UCB1244283
Release date: Dec. 10, 2025
Resolution: 3.03 Å
EM Method: Single-particle
Fitted PDBs: 9prs
Q-score: 0.55

Pidathala S, Chen X, Dai Y, Nguyen LN, Gorgulla C, Niu Y, Liu F, Lee CH

Nat Commun (2025) 16 pp. 10748-10748 [ DOI: doi:10.1038/s41467-025-65781-1 Pubmed: 41315229 ]

EMD-70733
Download Map
3D View
Structure of the sweet receptor bound to sucralose in the loose state, extracellular domain
Release date: Nov. 19, 2025
Resolution: 2.98 Å
EM Method: Single-particle
Fitted PDBs: 9oq1
Q-score: 0.467

Wang H, Chen X, Dai Y, Pidathala S, Niu Y, Zhao C, Li S, Wang L, Lee CH

Cell Res (2025) 35 pp. 775-778 [ Pubmed: 40754567 DOI: doi:10.1038/s41422-025-01156-x ]

EMD-70726
Download Map
3D View
Structure of the sweet receptor in the apo state
Release date: Sept. 3, 2025
Resolution: 3.07 Å
EM Method: Single-particle

Wang H, Chen X, Dai Y, Pidathala S, Niu Y, Zhao C, Li S, Wang L, Lee CH

Cell Res (2025) 35 pp. 775-778 [ Pubmed: 40754567 DOI: doi:10.1038/s41422-025-01156-x ]

EMD-70727
Download Map
3D View
Structure of the sweet receptor in the apo state, extracellular domain
Release date: Sept. 3, 2025
Resolution: 2.86 Å
EM Method: Single-particle
Fitted PDBs: 9opw
Q-score: 0.513

Wang H, Chen X, Dai Y, Pidathala S, Niu Y, Zhao C, Li S, Wang L, Lee CH

Cell Res (2025) 35 pp. 775-778 [ Pubmed: 40754567 DOI: doi:10.1038/s41422-025-01156-x ]

EMD-70728
Download Map
3D View
Structure of the sweet receptor in the apo state, VFT domain
Release date: Sept. 3, 2025
Resolution: 2.84 Å
EM Method: Single-particle

Wang H, Chen X, Dai Y, Pidathala S, Niu Y, Zhao C, Li S, Wang L, Lee CH

Cell Res (2025) 35 pp. 775-778 [ Pubmed: 40754567 DOI: doi:10.1038/s41422-025-01156-x ]

Sort by: Download
Showing 1 - 10 of 44. Page 1 of 5
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [44]

Current status

  • REL [44]

Sample type

  • Complex [44]
  • Protein [39]
  • Ligand [29]

Organism

  • Homo sapiens [44]
  • Mus musculus [10]

EM Method

  • Single-particle [44]

Resolution

  • ≥ 2Å and < 3Å [15]
  • ≥ 3Å and < 4Å [25]
  • ≥ 4Å and < 5Å [4]

Model molecular weight

  • 0-50 kDa [5]
  • 50-100 kDa [21]
  • 100-250 kDa [12]
  • 250-500 kDa [1]

Release Date

  • 2025 [22]
  • 2024 [10]
  • 2023 [8]
  • 2022 [4]

Author by name

  • Dai Y [44]
  • Lee CH [44]
  • Pidathala S [25]
  • Chen X [22]
  • Niu Y [22]
  • Li S [16]
  • Wang H [16]
  • Wang L [16]
  • Zhao C [16]
  • Zhao H [9]
  • Li X [8]
  • Gorgulla C [6]
  • Liu F [6]
  • Nguyen LN [6]
  • Ahmed S [5]
  • Chen H [5]
  • Elghobashi-meinhardt N [5]
  • Kim JH [5]
  • Mcdonald JG [5]
  • Jan LY [4]
  • Lo YH [4]
  • Wang Y [4]
  • Ye W [4]
  • Chang CL [3]
  • Liao S [3]
  • Long C [3]
  • Zhang Z [3]

Author by ORCID

  • Dai Y [44]
  • Lee CH [35]
  • Pidathala S [22]
  • Zhao C [16]
  • Niu Y [16]
  • Liu F [6]
  • Gorgulla C [6]
  • Nguyen LN [6]
  • Li X [5]
  • Elghobashi-meinhardt N [5]
  • Chen H [5]
  • Ahmed S [5]
  • Ye W [4]
  • Li X [3]
  • Zhang Z [3]
  • Long C [3]
  • Chang CL [3]

Journal

  • CELL RES [26]
  • NAT COMMUN [6]
  • CELL [5]
  • MOL CELL [4]
  • NATURE [3]

Software

  • CRYOSPARC [5]

Microscope

  • FEI TITAN KRIOS [22]
  • TFS KRIOS [22]

Electron Source

  • FIELD EMISSION GUN [44]

Film or detector model

  • GATAN K3 6K X 4K [44]

External links

  • AlphaFold DB [39]
  • PDB [39]
  • UniProt [39]
  • Pfam [34]
  • Complex Portal [28]
  • Gene Ontology [28]
  • PDBe-Kb [28]
  • InterPro [22]
  • ChEBI [19]
  • ChEMBL [15]
  • DrugBank [9]