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grant_code:"FR 1653/12-2"

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EMD-19683
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Cryo-EM structure of cell-free synthesized Human beta-1 adrenergic receptor cotranslationally inserted into a lipidic nanodiscs
Release date: May 21, 2025
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8s2t
Q-score: 0.447

Merino F, Kock Z, Ermel U, Dahlhaus P, Grimm A, Seybert A, Kubicek J, Frangakis AS, Dotsch V, Hilger D, Bernhard F

Structure (2025) 33 pp. 1867- [ Pubmed: 40858117 DOI: doi:10.1016/j.str.2025.07.020 ]

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Filter By

Current Database

  • EMDB [1]

Current status

  • REL [1]

Sample type

  • Complex [1]
  • Ligand [1]
  • Protein [1]

Organism

  • Homo sapiens [1]
  • Lama glama [1]

EM Method

  • Single-particle [1]

Resolution

  • ≥ 3Å and < 4Å [1]

Model molecular weight

  • 100-250 kDa [1]

Release Date

  • 2025 [1]

Author by name

  • Bernhard F [1]
  • Dahlhaus P [1]
  • Doetsch V [1]
  • Dotsch V [1]
  • Ermel U [1]
  • Frangakis AS [1]
  • Grimm A [1]
  • Hilger D [1]
  • Kock Z [1]
  • Koeck Z [1]
  • Kubicek J [1]
  • Merino F [1]
  • Seybert A [1]

Author by ORCID

  • Merino F [1]

Journal

  • STRUCTURE [1]

Software

  • CTFFIND [1]
  • RELION [1]

Microscope

  • TFS KRIOS [1]

Electron Source

  • FIELD EMISSION GUN [1]

Film or detector model

  • GATAN K2 SUMMIT 4K X 4K [1]

External links

  • AlphaFold DB [1]
  • ChEBI [1]
  • ChEMBL [1]
  • Gene Ontology [1]
  • InterPro [1]
  • PDB [1]
  • PDBe-Kb [1]
  • Pfam [1]
  • UniProt [1]