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grant_code:"F-1938-20200401"

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Current Database

  • EMDB [5]

Current status

  • REL [5]

Sample type

  • Complex [5]
  • DNA [5]
  • Protein [5]
  • RNA [5]
  • Ligand [2]

Organism

  • Streptococcus pyogenes [5]
  • Synthetic construct [5]

EM Method

  • Single-particle [5]

Resolution

  • ≥ 2Å and < 3Å [4]
  • ≥ 3Å and < 4Å [1]

Model molecular weight

  • 100-250 kDa [5]

Release Date

  • 2025 [5]

Author by name

  • Kiernan KA [5]
  • Taylor DW [5]

Author by ORCID

  • Kiernan KA [5]
  • Taylor DW [5]

Journal

  • NAT COMMUN [5]

Microscope

  • TFS KRIOS [5]

Electron Source

  • FIELD EMISSION GUN [5]

Film or detector model

  • GATAN K3 BIOCONTINUUM 6K X 4K [4]
  • GATAN K3 BIOQUANTUM 6K X 4K [1]

External links

  • AlphaFold DB [5]
  • Gene Ontology [5]
  • PDB [5]
  • PDBe-Kb [5]
  • Pfam [5]
  • UniProt [5]
  • InterPro [4]
  • ChEBI [2]
  • DrugBank [2]
  • ChEMBL [1]
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EMD-47835
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SpCas9 with 17-bp R-loop containing 2 terminal mismatches State II - precleavage
Release date: July 9, 2025
Resolution: 2.83 Å
EM Method: Single-particle
Fitted PDBs: 9eal
Q-score: 0.476

Kiernan KA, Taylor DW

Nat Commun (2025) 16 pp. 5681-5681 [ DOI: doi:10.1038/s41467-025-60668-7 Pubmed: 40593576 ]

EMD-47834
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SpCas9 with 17-bp R-loop containing 2 terminal mismatches State I - pre-activation
Release date: June 18, 2025
Resolution: 2.76 Å
EM Method: Single-particle
Fitted PDBs: 9eak
Q-score: 0.519

Kiernan KA, Taylor DW

Nat Commun (2025) 16 pp. 5681-5681 [ DOI: doi:10.1038/s41467-025-60668-7 Pubmed: 40593576 ]

EMD-47941
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SpCas9 with 17-bp R-loop containing 2 terminal mismatches State III - checkpoint
Release date: June 18, 2025
Resolution: 2.95 Å
EM Method: Single-particle
Fitted PDBs: 9ed9
Q-score: 0.479

Kiernan KA, Taylor DW

Nat Commun (2025) 16 pp. 5681-5681 [ DOI: doi:10.1038/s41467-025-60668-7 Pubmed: 40593576 ]

EMD-47942
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SpCas9 with 17-bp R-loop containing 2 terminal mismatches State IV - product
Release date: June 18, 2025
Resolution: 2.88 Å
EM Method: Single-particle
Fitted PDBs: 9eda
Q-score: 0.462

Kiernan KA, Taylor DW

Nat Commun (2025) 16 pp. 5681-5681 [ DOI: doi:10.1038/s41467-025-60668-7 Pubmed: 40593576 ]

EMD-47943
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3D View
SpCas9 with 17-bp R-loop containing 2 terminal mismatches State V - dissociated
Release date: June 18, 2025
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 9edb
Q-score: 0.459

Kiernan KA, Taylor DW

Nat Commun (2025) 16 pp. 5681-5681 [ DOI: doi:10.1038/s41467-025-60668-7 Pubmed: 40593576 ]

Sort by: Download
Showing 1 - 5 of 5. Page 1 of 1
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [5]

Current status

  • REL [5]

Sample type

  • Complex [5]
  • DNA [5]
  • Protein [5]
  • RNA [5]
  • Ligand [2]

Organism

  • Streptococcus pyogenes [5]
  • Synthetic construct [5]

EM Method

  • Single-particle [5]

Resolution

  • ≥ 2Å and < 3Å [4]
  • ≥ 3Å and < 4Å [1]

Model molecular weight

  • 100-250 kDa [5]

Release Date

  • 2025 [5]

Author by name

  • Kiernan KA [5]
  • Taylor DW [5]

Author by ORCID

  • Kiernan KA [5]
  • Taylor DW [5]

Journal

  • NAT COMMUN [5]

Microscope

  • TFS KRIOS [5]

Electron Source

  • FIELD EMISSION GUN [5]

Film or detector model

  • GATAN K3 BIOCONTINUUM 6K X 4K [4]
  • GATAN K3 BIOQUANTUM 6K X 4K [1]

External links

  • AlphaFold DB [5]
  • Gene Ontology [5]
  • PDB [5]
  • PDBe-Kb [5]
  • Pfam [5]
  • UniProt [5]
  • InterPro [4]
  • ChEBI [2]
  • DrugBank [2]
  • ChEMBL [1]