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grant_code:"2022YFA0806504"

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Current Database

  • EMDB [6]

Current status

  • REL [6]

Sample type

  • Complex [6]
  • Ligand [6]
  • Protein [6]

Organism

  • Homo sapiens [6]

EM Method

  • Single-particle [6]

Resolution

  • ≥ 2Å and < 3Å [3]
  • ≥ 3Å and < 4Å [3]

Model molecular weight

  • 50-100 kDa [3]
  • 250-500 kDa [3]

Release Date

  • 2025 [6]

Author by name

  • Chen L [6]
  • Chen Y [6]
  • Guo W [6]
  • Wei M [6]
  • Guo WJ [4]
  • Li Y [3]
  • Song K [3]
  • Xu J [3]
  • Zang J [3]
  • Chen YK [2]
  • Song KC [1]

Author by ORCID

  • Chen L [6]
  • Wei M [3]
  • Xu J [3]

Journal

  • NAT COMMUN [3]
  • PROTEIN SCI [3]

Software

  • CRYOSPARC [1]

Microscope

  • FEI TITAN KRIOS [3]
  • TFS KRIOS [3]

Electron Source

  • FIELD EMISSION GUN [6]

Film or detector model

  • GATAN K3 6K X 4K [6]

External links

  • AlphaFold DB [6]
  • Complex Portal [6]
  • PDB [6]
  • PDBe-Kb [6]
  • Pfam [6]
  • UniProt [6]
  • ChEBI [5]
  • ChEMBL [5]
  • DrugBank [5]
  • Gene Ontology [4]
  • InterPro [3]
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EMD-63600
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3D View
Structure of human TRPC5 in the low Ca environment.
Release date: July 2, 2025
Resolution: 2.48 Å
EM Method: Single-particle
Fitted PDBs: 9m36
Q-score: 0.619

Chen Y, Song K, Guo W, Wei M, Chen L

Protein Sci (2025) 34 pp. e70218-e70218 [ Pubmed: 40671342 DOI: doi:10.1002/pro.70218 ]

EMD-63631
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3D View
Structure of human TRPC5 bound with - -englerin A, class 2.
Release date: July 2, 2025
Resolution: 2.62 Å
EM Method: Single-particle
Fitted PDBs: 9m4w
Q-score: 0.58

Chen Y, Song K, Guo W, Wei M, Chen L

Protein Sci (2025) 34 pp. e70218-e70218 [ Pubmed: 40671342 DOI: doi:10.1002/pro.70218 ]

EMD-63651
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3D View
Structure of human TRPC5 bound with - -englerin A,class1
Release date: July 2, 2025
Resolution: 2.53 Å
EM Method: Single-particle
Fitted PDBs: 9m5v
Q-score: 0.606

Chen Y, Song K, Guo W, Wei M, Chen L

Protein Sci (2025) 34 pp. e70218-e70218 [ Pubmed: 40671342 DOI: doi:10.1002/pro.70218 ]

EMD-60823
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3D View
Structure of human URAT1 bound with urate
Release date: Jan. 15, 2025
Resolution: 3.26 Å
EM Method: Single-particle
Fitted PDBs: 9irw
Q-score: 0.519

Guo W, Wei M, Li Y, Xu J, Zang J, Chen Y, Chen L

Nat Commun (2025) 16 pp. 1512-1512 [ Pubmed: 39929841 DOI: doi:10.1038/s41467-025-56843-5 ]

EMD-60824
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3D View
Structure of human URAT1 bound with benzbromarone
Release date: Jan. 15, 2025
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 9irx
Q-score: 0.557

Guo W, Wei M, Li Y, Xu J, Zang J, Chen Y, Chen L

Nat Commun (2025) 16 pp. 1512-1512 [ Pubmed: 39929841 DOI: doi:10.1038/s41467-025-56843-5 ]

EMD-60825
Download Map
3D View
Structure of human URAT1 bound with verinurad
Release date: Jan. 15, 2025
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 9iry
Q-score: 0.507

Guo W, Wei M, Li Y, Xu J, Zang J, Chen Y, Chen L

Nat Commun (2025) 16 pp. 1512-1512 [ Pubmed: 39929841 DOI: doi:10.1038/s41467-025-56843-5 ]

Sort by: Download
Showing 1 - 6 of 6. Page 1 of 1
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [6]

Current status

  • REL [6]

Sample type

  • Complex [6]
  • Ligand [6]
  • Protein [6]

Organism

  • Homo sapiens [6]

EM Method

  • Single-particle [6]

Resolution

  • ≥ 2Å and < 3Å [3]
  • ≥ 3Å and < 4Å [3]

Model molecular weight

  • 50-100 kDa [3]
  • 250-500 kDa [3]

Release Date

  • 2025 [6]

Author by name

  • Chen L [6]
  • Chen Y [6]
  • Guo W [6]
  • Wei M [6]
  • Guo WJ [4]
  • Li Y [3]
  • Song K [3]
  • Xu J [3]
  • Zang J [3]
  • Chen YK [2]
  • Song KC [1]

Author by ORCID

  • Chen L [6]
  • Wei M [3]
  • Xu J [3]

Journal

  • NAT COMMUN [3]
  • PROTEIN SCI [3]

Software

  • CRYOSPARC [1]

Microscope

  • FEI TITAN KRIOS [3]
  • TFS KRIOS [3]

Electron Source

  • FIELD EMISSION GUN [6]

Film or detector model

  • GATAN K3 6K X 4K [6]

External links

  • AlphaFold DB [6]
  • Complex Portal [6]
  • PDB [6]
  • PDBe-Kb [6]
  • Pfam [6]
  • UniProt [6]
  • ChEBI [5]
  • ChEMBL [5]
  • DrugBank [5]
  • Gene Ontology [4]
  • InterPro [3]