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author:"Scrutton AM"

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Current Database

  • EMDB [17]

Current status

  • REL [17]

Sample type

  • Complex [17]
  • Protein [12]
  • Ligand [4]

Organism

  • Rattus norvegicus [13]
  • Mus musculus [9]
  • Sus scrofa [4]

EM Method

  • Single-particle [17]

Resolution

  • ≥ 2Å and < 3Å [4]
  • ≥ 3Å and < 4Å [11]
  • ≥ 4Å and < 5Å [2]

Model molecular weight

  • 100-250 kDa [1]
  • 250-500 kDa [3]
  • 500-1000 kDa [7]

Release Date

  • 2025 [8]
  • 2024 [9]

Author by name

  • Greger IH [17]
  • Ivica J [17]
  • Scrutton AM [17]
  • Stockwell I [17]
  • Ho H [9]
  • Kejzar N [9]
  • Kuchtiak V [9]
  • Nakagawa T [9]
  • Aricescu AR [8]
  • Chang VT [8]
  • Krieger JM [8]
  • Mclaughlin SH [8]
  • Peak-chew S [8]
  • Scrutton A [8]
  • Sengupta N [8]
  • Singh B [8]
  • Suzuki K [8]

Author by ORCID

  • Scrutton AM [17]
  • Greger IH [17]
  • Ho H [9]
  • Krieger JM [8]
  • Chang VT [8]
  • Suzuki K [8]
  • Ivica J [8]
  • Mclaughlin SH [8]
  • Peak-chew S [8]
  • Stockwell I [8]
  • Sengupta N [8]
  • Aricescu AR [8]

Journal

  • NAT STRUCT MOL BIOL [9]
  • SCIENCE [8]

Software

  • CRYOSPARC [8]
  • RELION [8]

Microscope

  • TFS KRIOS [17]

Electron Source

  • FIELD EMISSION GUN [17]

Film or detector model

  • GATAN K3 BIOQUANTUM 6K X 4K [11]
  • FEI FALCON IV 4K X 4K [6]

External links

  • AlphaFold DB [12]
  • PDB [12]
  • UniProt [12]
  • Pfam [11]
  • Gene Ontology [9]
  • InterPro [9]
  • PDBe-Kb [9]
  • ChEBI [4]
  • ChEMBL [4]
  • Complex Portal [2]
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EMD-54556
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Cerebellar GluA1/4 LBD tetramer focused refinement
Release date: Dec. 31, 2025
Resolution: 3.55 Å
EM Method: Single-particle
Fitted PDBs: 9s3z
Q-score: 0.477

Scrutton AM, Sengupta N, Ivica J, Stockwell I, Peak-Chew S, Singh B, Suzuki K, Chang VT, McLaughlin SH, Krieger JM, Aricescu AR, Greger IH

Science (2025) pp. eaeb3577-eaeb3577 [ DOI: doi:10.1126/science.aeb3577 Pubmed: 41379938 ]

EMD-54543
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Cerebellar GluA2/4 NTD heterophilic tetramer interface focused refinement
Release date: Dec. 24, 2025
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 9s3o
Q-score: 0.438

Scrutton AM, Sengupta N, Ivica J, Stockwell I, Peak-Chew S, Singh B, Suzuki K, Chang VT, McLaughlin SH, Krieger JM, Aricescu AR, Greger IH

Science (2025) pp. eaeb3577-eaeb3577 [ DOI: doi:10.1126/science.aeb3577 Pubmed: 41379938 ]

EMD-54558
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Cerebellar GluA1/4 TMD with TARP gamma 7 focused refinement
Release date: Dec. 24, 2025
Resolution: 3.66 Å
EM Method: Single-particle
Fitted PDBs: 9s41
Q-score: 0.447

Scrutton AM, Sengupta N, Ivica J, Stockwell I, Peak-Chew S, Singh B, Suzuki K, Chang VT, McLaughlin SH, Krieger JM, Aricescu AR, Greger IH

Science (2025) pp. eaeb3577-eaeb3577 [ DOI: doi:10.1126/science.aeb3577 Pubmed: 41379938 ]

EMD-54559
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3D View
Cerebellar GluAx/A4 TMD with four TARPs focused refinement
Release date: Dec. 24, 2025
Resolution: 3.57 Å
EM Method: Single-particle

Scrutton AM, Sengupta N, Ivica J, Stockwell I, Peak-Chew S, Singh B, Suzuki K, Chang VT, McLaughlin SH, Krieger JM, Aricescu AR, Greger IH

Science (2025) pp. eaeb3577-eaeb3577 [ DOI: doi:10.1126/science.aeb3577 Pubmed: 41379938 ]

EMD-55413
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3D View
GluA4 N-terminal domain bound to nanobody NB74 focused refinement
Release date: Dec. 24, 2025
Resolution: 4.4 Å
EM Method: Single-particle

Scrutton AM, Sengupta N, Ivica J, Stockwell I, Peak-Chew S, Singh B, Suzuki K, Chang VT, McLaughlin SH, Krieger JM, Aricescu AR, Greger IH

Science (2025) pp. eaeb3577-eaeb3577 [ DOI: doi:10.1126/science.aeb3577 Pubmed: 41379938 ]

EMD-55414
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3D View
GluA4 LBD-TMD with TARP gamma 2 focused refinement
Release date: Dec. 24, 2025
Resolution: 3.6 Å
EM Method: Single-particle

Scrutton AM, Sengupta N, Ivica J, Stockwell I, Peak-Chew S, Singh B, Suzuki K, Chang VT, McLaughlin SH, Krieger JM, Aricescu AR, Greger IH

Science (2025) pp. eaeb3577-eaeb3577 [ DOI: doi:10.1126/science.aeb3577 Pubmed: 41379938 ]

EMD-55418
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3D View
GluA4 with TARP gamma2 consensus refinement
Release date: Dec. 24, 2025
Resolution: 3.9 Å
EM Method: Single-particle

Scrutton AM, Sengupta N, Ivica J, Stockwell I, Peak-Chew S, Singh B, Suzuki K, Chang VT, McLaughlin SH, Krieger JM, Aricescu AR, Greger IH

Science (2025) pp. eaeb3577-eaeb3577 [ DOI: doi:10.1126/science.aeb3577 Pubmed: 41379938 ]

EMD-55419
Composite map
Download Map
3D View
Full-length GluA4 with TARP gamma 2 composite map
Release date: Dec. 24, 2025
Resolution: 4.5 Å
EM Method: Single-particle

Scrutton AM, Sengupta N, Ivica J, Stockwell I, Peak-Chew S, Singh B, Suzuki K, Chang VT, McLaughlin SH, Krieger JM, Aricescu AR, Greger IH

Science (2025) pp. eaeb3577-eaeb3577 [ DOI: doi:10.1126/science.aeb3577 Pubmed: 41379938 ]

EMD-44232
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GluA2 flip Q in complex with TARPgamma2 at pH8, consensus structure of LBD-TMD-TARPgamma2
Release date: July 31, 2024
Resolution: 2.71 Å
EM Method: Single-particle
Fitted PDBs: 9b5z
Q-score: 0.53

Ivica J, Kejzar N, Ho H, Stockwell I, Kuchtiak V, Scrutton AM, Nakagawa T, Greger IH

Nat Struct Mol Biol (2024) 31 pp. 1601-1613 [ DOI: doi:10.1038/s41594-024-01369-5 Pubmed: 39138332 ]

EMD-44233
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GluA2 flip Q in complex with TARPgamma2 at pH8, consensus structure of TMD-TARPgamma2
Release date: July 31, 2024
Resolution: 2.57 Å
EM Method: Single-particle
Fitted PDBs: 9b60
Q-score: 0.553

Ivica J, Kejzar N, Ho H, Stockwell I, Kuchtiak V, Scrutton AM, Nakagawa T, Greger IH

Nat Struct Mol Biol (2024) 31 pp. 1601-1613 [ DOI: doi:10.1038/s41594-024-01369-5 Pubmed: 39138332 ]

Sort by: Download
Showing 1 - 10 of 17. Page 1 of 2
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [17]

Current status

  • REL [17]

Sample type

  • Complex [17]
  • Protein [12]
  • Ligand [4]

Organism

  • Rattus norvegicus [13]
  • Mus musculus [9]
  • Sus scrofa [4]

EM Method

  • Single-particle [17]

Resolution

  • ≥ 2Å and < 3Å [4]
  • ≥ 3Å and < 4Å [11]
  • ≥ 4Å and < 5Å [2]

Model molecular weight

  • 100-250 kDa [1]
  • 250-500 kDa [3]
  • 500-1000 kDa [7]

Release Date

  • 2025 [8]
  • 2024 [9]

Author by name

  • Greger IH [17]
  • Ivica J [17]
  • Scrutton AM [17]
  • Stockwell I [17]
  • Ho H [9]
  • Kejzar N [9]
  • Kuchtiak V [9]
  • Nakagawa T [9]
  • Aricescu AR [8]
  • Chang VT [8]
  • Krieger JM [8]
  • Mclaughlin SH [8]
  • Peak-chew S [8]
  • Scrutton A [8]
  • Sengupta N [8]
  • Singh B [8]
  • Suzuki K [8]

Author by ORCID

  • Scrutton AM [17]
  • Greger IH [17]
  • Ho H [9]
  • Krieger JM [8]
  • Chang VT [8]
  • Suzuki K [8]
  • Ivica J [8]
  • Mclaughlin SH [8]
  • Peak-chew S [8]
  • Stockwell I [8]
  • Sengupta N [8]
  • Aricescu AR [8]

Journal

  • NAT STRUCT MOL BIOL [9]
  • SCIENCE [8]

Software

  • CRYOSPARC [8]
  • RELION [8]

Microscope

  • TFS KRIOS [17]

Electron Source

  • FIELD EMISSION GUN [17]

Film or detector model

  • GATAN K3 BIOQUANTUM 6K X 4K [11]
  • FEI FALCON IV 4K X 4K [6]

External links

  • AlphaFold DB [12]
  • PDB [12]
  • UniProt [12]
  • Pfam [11]
  • Gene Ontology [9]
  • InterPro [9]
  • PDBe-Kb [9]
  • ChEBI [4]
  • ChEMBL [4]
  • Complex Portal [2]