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author:"Pyle AM"

Filter By

Current Database

  • EMDB [22]
  • EMPIAR [13]

Current status

  • REL [35]

Sample type

  • Complex [22]
  • Ligand [22]
  • RNA [22]
  • Protein [19]
  • DNA [1]

Organism

  • Homo sapiens [14]
  • [eubacterium] rectale [5]
  • Candida albicans [3]

EM Method

  • Single-particle [22]

Resolution

  • ≥ 2Å and < 3Å [4]
  • ≥ 3Å and < 4Å [17]
  • ≥ 4Å and < 5Å [1]

Model molecular weight

  • 100-250 kDa [14]
  • 250-500 kDa [8]

Release Date

  • 2025 [3]
  • 2024 [5]
  • 2023 [7]
  • 2022 [20]

Author by name

  • Pyle AM [32]
  • Wang W [24]
  • Chung K [9]
  • Xu L [9]
  • Liu T [7]
  • Gotte B [3]
  • Guo R [3]
  • Hwang J [3]
  • Pyle A [3]
  • Sisto LJ [3]
  • Van Zandt Mc [3]
  • Zhang C [3]
  • Chai P [2]
  • Chung KC [2]
  • Devarkar SC [2]
  • Peng J [2]
  • Pyle AMP [2]
  • Xu LX [2]

Author by ORCID

  • Wang W [14]
  • Pyle AM [10]
  • Liu T [6]
  • Xu L [5]
  • Chung K [5]
  • Gotte B [3]
  • Chai P [2]
  • Devarkar SC [2]
  • Peng J [2]

Journal

  • MOL CELL [16]
  • NATURE [4]
  • SCIENCE [4]
  • NAT COMMUN [3]
  • PNAS [3]
  • TO BE PUBLISHED [2]

Software

  • CRYOSPARC [2]

Microscope

  • FEI TITAN KRIOS [17]
  • TFS KRIOS [3]
  • TFS GLACIOS [2]

Electron Source

  • FIELD EMISSION GUN [22]

Film or detector model

  • GATAN K3 6K X 4K [15]
  • GATAN K2 SUMMIT 4K X 4K [6]
  • FEI FALCON IV 4K X 4K [1]

EMPIAR Experiment type

  • EMDB [13]

EMPIAR Image category

  • MICROGRAPHS - MULTIFRAME [13]

External links

  • ChEBI [22]
  • DrugBank [22]
  • PDB [22]
  • AlphaFold DB [19]
  • Gene Ontology [19]
  • InterPro [19]
  • PDBe-Kb [19]
  • Pfam [19]
  • UniProt [19]
  • ChEMBL [18]
  • EMPIAR [17]
  • EMDB [13]
Sort by: Download
Showing 1 - 10 of 35. Page 1 of 4
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EMD-48538
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3D View
CryoEM Structure of the Candida albicans Group I Intron-GMP Complex
Release date: April 30, 2025
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 9mqs
Q-score: 0.396

Liu T, Xu L, Chung K, Sisto LJ, Hwang J, Zhang C, Van Zandt MC, Pyle AM

PNAS (2025) 122 pp. e2502425122-e2502425122 [ DOI: doi:10.1073/pnas.2502425122 Pubmed: 40339124 ]

EMD-48539
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3D View
CryoEM Structure of the Candida albicans Group I Intron-Compound 11 Complex under Magnesium Condition
Release date: April 30, 2025
Resolution: 2.43 Å
EM Method: Single-particle
Fitted PDBs: 9mqt
Q-score: 0.555

Liu T, Xu L, Chung K, Sisto LJ, Hwang J, Zhang C, Van Zandt MC, Pyle AM

PNAS (2025) 122 pp. e2502425122-e2502425122 [ DOI: doi:10.1073/pnas.2502425122 Pubmed: 40339124 ]

EMD-48540
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3D View
CryoEM Structure of the Candida albicans Group I Intron-Compound 11 Complex under Calcium Condition
Release date: April 30, 2025
Resolution: 2.59 Å
EM Method: Single-particle
Fitted PDBs: 9mqu
Q-score: 0.558

Liu T, Xu L, Chung K, Sisto LJ, Hwang J, Zhang C, Van Zandt MC, Pyle AM

PNAS (2025) 122 pp. e2502425122-e2502425122 [ DOI: doi:10.1073/pnas.2502425122 Pubmed: 40339124 ]

EMPIAR-11809
Related EMDB
EMD-40987
CryoEM micrographs of a group II RNP in the post-ligation state
Release date: July 14, 2024
Dataset size: 5.9 TB
Experiment type: EMDB

Xu L, Liu T, Chung K, Pyle AM

Nature (2023) [ DOI: 10.1038/s41586-023-06746-6 Pubmed: 37993708 ]

Image sets:
  • Unaligned multi-frame micrographs of a group IIC intron (post-exon ligation)
EMPIAR-11496
Related EMDB
EMD-40348
Single particle cryo-EM structure of RIG-I in complex with p3SLR14
Release date: March 20, 2024
Dataset size: 1.1 TB
Experiment type: EMDB

Wang W, Pyle AM

To Be Published

Image sets:
  • Unaligned multi-frame micrographs of RIG-I in complex with p3SLR14
EMPIAR-11495
Related EMDB
EMD-40347
Single particle cryo-EM structure of 14-aa-GS-RIG-I in complex with p3SLR30
Release date: March 18, 2024
Dataset size: 2.7 TB
Experiment type: EMDB

Wang W, Pyle AM

To Be Published

Image sets:
  • Unaligned multi-frame micrographs of 14-aa-GS-RIG-I in complex with p3SLR30
EMD-40347
Download Map
3D View
Raw data
EMPIAR-11495
Cryo-EM structure of 14aa-GS RIG-I in complex with p3SLR30
Release date: March 13, 2024
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8scz
Q-score: 0.386

Wang W, Pyle AM

To Be Published

EMD-40348
Download Map
3D View
Raw data
EMPIAR-11496
Cryo-EM structure of RIG-I in complex with p3SLR14
Release date: March 13, 2024
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 8sd0
Q-score: 0.425

Wang W, Pyle AM

To Be Published

EMD-40985
Download Map
3D View
Structure of a group II intron ribonucleoprotein in the pre-ligation pre-2F state
Release date: Nov. 22, 2023
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8t2r
Q-score: 0.459

Xu L, Liu T, Chung K, Pyle AM

Nature (2023) 624 pp. 682-688 [ Pubmed: 37993708 DOI: doi:10.1038/s41586-023-06746-6 ]

EMD-40986
Download Map
3D View
Structure of a group II intron ribonucleoprotein in the pre-branching pre-1F state
Release date: Nov. 22, 2023
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8t2s
Q-score: 0.48

Xu L, Liu T, Chung K, Pyle AM

Nature (2023) 624 pp. 682-688 [ Pubmed: 37993708 DOI: doi:10.1038/s41586-023-06746-6 ]

Sort by: Download
Showing 1 - 10 of 35. Page 1 of 4
Display:
Statistics
×

Download












































Preview first 10
Download

Filter By

Current Database

  • EMDB [22]
  • EMPIAR [13]

Current status

  • REL [35]

Sample type

  • Complex [22]
  • Ligand [22]
  • RNA [22]
  • Protein [19]
  • DNA [1]

Organism

  • Homo sapiens [14]
  • [eubacterium] rectale [5]
  • Candida albicans [3]

EM Method

  • Single-particle [22]

Resolution

  • ≥ 2Å and < 3Å [4]
  • ≥ 3Å and < 4Å [17]
  • ≥ 4Å and < 5Å [1]

Model molecular weight

  • 100-250 kDa [14]
  • 250-500 kDa [8]

Release Date

  • 2025 [3]
  • 2024 [5]
  • 2023 [7]
  • 2022 [20]

Author by name

  • Pyle AM [32]
  • Wang W [24]
  • Chung K [9]
  • Xu L [9]
  • Liu T [7]
  • Gotte B [3]
  • Guo R [3]
  • Hwang J [3]
  • Pyle A [3]
  • Sisto LJ [3]
  • Van Zandt Mc [3]
  • Zhang C [3]
  • Chai P [2]
  • Chung KC [2]
  • Devarkar SC [2]
  • Peng J [2]
  • Pyle AMP [2]
  • Xu LX [2]

Author by ORCID

  • Wang W [14]
  • Pyle AM [10]
  • Liu T [6]
  • Xu L [5]
  • Chung K [5]
  • Gotte B [3]
  • Chai P [2]
  • Devarkar SC [2]
  • Peng J [2]

Journal

  • MOL CELL [16]
  • NATURE [4]
  • SCIENCE [4]
  • NAT COMMUN [3]
  • PNAS [3]
  • TO BE PUBLISHED [2]

Software

  • CRYOSPARC [2]

Microscope

  • FEI TITAN KRIOS [17]
  • TFS KRIOS [3]
  • TFS GLACIOS [2]

Electron Source

  • FIELD EMISSION GUN [22]

Film or detector model

  • GATAN K3 6K X 4K [15]
  • GATAN K2 SUMMIT 4K X 4K [6]
  • FEI FALCON IV 4K X 4K [1]

EMPIAR Experiment type

  • EMDB [13]

EMPIAR Image category

  • MICROGRAPHS - MULTIFRAME [13]

External links

  • ChEBI [22]
  • DrugBank [22]
  • PDB [22]
  • AlphaFold DB [19]
  • Gene Ontology [19]
  • InterPro [19]
  • PDBe-Kb [19]
  • Pfam [19]
  • UniProt [19]
  • ChEMBL [18]
  • EMPIAR [17]
  • EMDB [13]