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author:"Latorraca NR"

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Current Database

  • EMDB [25]

Current status

  • REL [25]

Sample type

  • Cellular component [17]
  • Protein [15]
  • Complex [8]
  • Ligand [8]

Organism

  • Homo sapiens [19]
  • Mus musculus [4]
  • Danio rerio [4]
  • Lama glama [4]
  • Synthetic construct [3]
  • Rattus norvegicus [2]
  • Spodoptera frugiperda [2]

EM Method

  • Single-particle [25]

Resolution

  • ≥ 2Å and < 3Å [5]
  • ≥ 3Å and < 4Å [13]
  • ≥ 4Å and < 5Å [7]

Model molecular weight

  • 50-100 kDa [1]
  • 100-250 kDa [14]

Release Date

  • 2024 [7]
  • 2023 [5]
  • 2020 [2]
  • 2019 [9]
  • 2018 [2]

Author by name

  • Latorraca NR [25]
  • Kobilka BK [17]
  • Krishna Kumar K [15]
  • Koehl A [13]
  • Isacoff EY [12]
  • Marqusee S [12]
  • Montabana E [12]
  • O Brien Es [12]
  • Wang H [12]
  • Dror RO [11]
  • Habrian C [11]
  • Xu J [11]
  • Zhang C [11]
  • Hollingsworth SA [7]
  • Hu H [7]
  • Skiniotis G [7]
  • Chen DH [6]
  • Chew TA [6]
  • Feng L [6]
  • Hilger D [6]
  • Liao M [6]
  • Orlando BJ [6]
  • Wang A [6]
  • Zhang J [6]
  • Liao MF [4]
  • Zhang Y [4]
  • Kato HE [3]
  • Maeda S [3]
  • Robertson MJ [3]
  • Weis WI [3]
  • Aoki J [2]
  • Benjamin O [2]
  • Capel WD [2]
  • Dawson R [2]
  • Fonseca R [2]
  • Granier S [2]
  • Huang W [2]
  • Inoue A [2]
  • Kadji FMN [2]
  • Kleinhenz ALW [2]
  • Lefkowitz RJ [2]
  • Manglik A [2]
  • Matile H [2]
  • Paggi JM [2]
  • Qu Q [2]
  • Schertler GFX [2]
  • Staus DP [2]
  • Suomivuori CM [2]
  • Wingler LM [2]
  • Banister SD [1]
  • Farrens DL [1]
  • Habrian CH [1]
  • Malhotra SV [1]
  • Mathiesen JM [1]
  • Shalev-benami M [1]
  • Tuneew I [1]

Author by ORCID

  • Latorraca NR [24]
  • Kobilka BK [16]
  • O'brien ES [12]
  • Marqusee S [11]
  • Xu J [11]
  • Krishna Kumar K [11]
  • Isacoff EY [11]
  • Dror RO [8]
  • Hollingsworth SA [7]
  • Skiniotis G [6]
  • Hilger D [5]
  • Zhang Y [4]
  • Kato HE [3]
  • Weis WI [3]
  • Maeda S [3]
  • Suomivuori CM [2]
  • Schertler GFX [2]
  • Huang W [2]
  • Fonseca R [2]
  • Dawson R [2]
  • Robertson MJ [2]
  • Banister SD [1]

Journal

  • NATURE [23]
  • BIORXIV [4]
  • CELL [2]

Software

  • RELION [4]
  • FREALIGN [2]
  • CISTEM [1]
  • GCTF [1]

Microscope

  • FEI TITAN KRIOS [25]

Electron Source

  • FIELD EMISSION GUN [25]

Film or detector model

  • GATAN K3 BIOQUANTUM 6K X 4K [11]
  • GATAN K2 QUANTUM 4K X 4K [8]
  • GATAN K2 SUMMIT 4K X 4K [5]
  • GATAN K3 6K X 4K [1]

External links

  • PDB [15]
  • UniProt [15]
  • AlphaFold DB [11]
  • Gene Ontology [11]
  • InterPro [11]
  • PDBe-Kb [11]
  • Pfam [11]
  • ChEBI [6]
  • ChEMBL [6]
  • DrugBank [6]
  • CATH [3]
  • EMPIAR [1]
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Showing 1 - 10 of 25. Page 1 of 3
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EMD-41783
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3D View
CDPPB bound inactive mGlu5, local refinement on TM region
Release date: Dec. 18, 2024
Resolution: 4.0 Å
EM Method: Single-particle

Krishna Kumar K, Wang H, Habrian C, Latorraca NR, Xu J, O'Brien ES, Zhang C, Montabana E, Koehl A, Marqusee S, Isacoff EY, Kobilka BK

Nature (2024) 629 pp. 951-956 [ Pubmed: 38632403 DOI: doi:10.1038/s41586-024-07327-x ]

EMD-41787
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3D View
CDPPB bound inactive mGlu5, non-uniform refinement of the whole complex
Release date: Dec. 18, 2024
Resolution: 3.3 Å
EM Method: Single-particle

Krishna Kumar K, Wang H, Habrian C, Latorraca NR, Xu J, O'Brien ES, Zhang C, Montabana E, Koehl A, Marqusee S, Isacoff EY, Kobilka BK

Nature (2024) 629 pp. 951-956 [ Pubmed: 38632403 DOI: doi:10.1038/s41586-024-07327-x ]

EMD-41789
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TM region local refinement of CDPPB, QUS bound mGlu5 in complex with Nb43
Release date: Dec. 18, 2024
Resolution: 4.46 Å
EM Method: Single-particle

Krishna Kumar K, Wang H, Habrian C, Latorraca NR, Xu J, O'Brien ES, Zhang C, Montabana E, Koehl A, Marqusee S, Isacoff EY, Kobilka BK

Nature (2024) 629 pp. 951-956 [ Pubmed: 38632403 DOI: doi:10.1038/s41586-024-07327-x ]

EMD-41793
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3D View
CDDPPB, QUS bound mGlu5 in complex with Nb43, local refinement on the VFT region
Release date: Dec. 18, 2024
Resolution: 2.89 Å
EM Method: Single-particle

Krishna Kumar K, Wang H, Habrian C, Latorraca NR, Xu J, O'Brien ES, Zhang C, Montabana E, Koehl A, Marqusee S, Isacoff EY, Kobilka BK

Nature (2024) 629 pp. 951-956 [ Pubmed: 38632403 DOI: doi:10.1038/s41586-024-07327-x ]

EMD-41804
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3D View
QUS bound active mGlu5 in complex with Nb43, local refinement on the TM region
Release date: Dec. 18, 2024
Resolution: 4.24 Å
EM Method: Single-particle

Krishna Kumar K, Wang H, Habrian C, Latorraca NR, Xu J, O'Brien ES, Zhang C, Montabana E, Koehl A, Marqusee S, Isacoff EY, Kobilka BK

Nature (2024) 629 pp. 951-956 [ Pubmed: 38632403 DOI: doi:10.1038/s41586-024-07327-x ]

EMD-41807
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3D View
QUS bounds mGlu5 in complex with Nb43, non uniform refinement on the whole complex
Release date: Dec. 18, 2024
Resolution: 3.33 Å
EM Method: Single-particle

Krishna Kumar K, Wang H, Habrian C, Latorraca NR, Xu J, O'Brien ES, Zhang C, Montabana E, Koehl A, Marqusee S, Isacoff EY, Kobilka BK

Nature (2024) 629 pp. 951-956 [ Pubmed: 38632403 DOI: doi:10.1038/s41586-024-07327-x ]

EMD-41808
Download Map
3D View
QUS bound inactive mGlu5 in complex with Nb43, local refinement on the TM region
Release date: Dec. 18, 2024
Resolution: 4.65 Å
EM Method: Single-particle

Krishna Kumar K, Wang H, Habrian C, Latorraca NR, Xu J, O'Brien ES, Zhang C, Montabana E, Koehl A, Marqusee S, Isacoff EY, Kobilka BK

Nature (2024) 629 pp. 951-956 [ Pubmed: 38632403 DOI: doi:10.1038/s41586-024-07327-x ]

EMD-41069
Composite map
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3D View
CDPPB-bound inactive mGlu5
Release date: Oct. 11, 2023
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8t6j
Q-score: 0.463

Krishna Kumar K, Wang H, Habrian C, Latorraca NR, Xu J, O'Brien ES, Zhang C, Montabana E, Koehl A, Marqusee S, Isacoff EY, Kobilka BK

Nature (2024) 629 pp. 951-956 [ Pubmed: 38632403 DOI: doi:10.1038/s41586-024-07327-x ]

EMD-41092
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3D View
Quis-bound intermediate mGlu5
Release date: Oct. 11, 2023
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8t7h
Q-score: 0.43

Krishna Kumar K, Wang H, Habrian C, Latorraca NR, Xu J, O'Brien ES, Zhang C, Montabana E, Koehl A, Marqusee S, Isacoff EY, Kobilka BK

Nature (2024) 629 pp. 951-956 [ Pubmed: 38632403 DOI: doi:10.1038/s41586-024-07327-x ]

EMD-41099
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3D View
Quis-bound intermediate mGlu5
Release date: Oct. 11, 2023
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8t8m
Q-score: 0.493

Krishna Kumar K, Wang H, Habrian C, Latorraca NR, Xu J, O'Brien ES, Zhang C, Montabana E, Koehl A, Marqusee S, Isacoff EY, Kobilka BK

Nature (2024) 629 pp. 951-956 [ Pubmed: 38632403 DOI: doi:10.1038/s41586-024-07327-x ]

Sort by: Download
Showing 1 - 10 of 25. Page 1 of 3
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [25]

Current status

  • REL [25]

Sample type

  • Cellular component [17]
  • Protein [15]
  • Complex [8]
  • Ligand [8]

Organism

  • Homo sapiens [19]
  • Mus musculus [4]
  • Danio rerio [4]
  • Lama glama [4]
  • Synthetic construct [3]
  • Rattus norvegicus [2]
  • Spodoptera frugiperda [2]

EM Method

  • Single-particle [25]

Resolution

  • ≥ 2Å and < 3Å [5]
  • ≥ 3Å and < 4Å [13]
  • ≥ 4Å and < 5Å [7]

Model molecular weight

  • 50-100 kDa [1]
  • 100-250 kDa [14]

Release Date

  • 2024 [7]
  • 2023 [5]
  • 2020 [2]
  • 2019 [9]
  • 2018 [2]

Author by name

  • Latorraca NR [25]
  • Kobilka BK [17]
  • Krishna Kumar K [15]
  • Koehl A [13]
  • Isacoff EY [12]
  • Marqusee S [12]
  • Montabana E [12]
  • O Brien Es [12]
  • Wang H [12]
  • Dror RO [11]
  • Habrian C [11]
  • Xu J [11]
  • Zhang C [11]
  • Hollingsworth SA [7]
  • Hu H [7]
  • Skiniotis G [7]
  • Chen DH [6]
  • Chew TA [6]
  • Feng L [6]
  • Hilger D [6]
  • Liao M [6]
  • Orlando BJ [6]
  • Wang A [6]
  • Zhang J [6]
  • Liao MF [4]
  • Zhang Y [4]
  • Kato HE [3]
  • Maeda S [3]
  • Robertson MJ [3]
  • Weis WI [3]
  • Aoki J [2]
  • Benjamin O [2]
  • Capel WD [2]
  • Dawson R [2]
  • Fonseca R [2]
  • Granier S [2]
  • Huang W [2]
  • Inoue A [2]
  • Kadji FMN [2]
  • Kleinhenz ALW [2]
  • Lefkowitz RJ [2]
  • Manglik A [2]
  • Matile H [2]
  • Paggi JM [2]
  • Qu Q [2]
  • Schertler GFX [2]
  • Staus DP [2]
  • Suomivuori CM [2]
  • Wingler LM [2]
  • Banister SD [1]
  • Farrens DL [1]
  • Habrian CH [1]
  • Malhotra SV [1]
  • Mathiesen JM [1]
  • Shalev-benami M [1]
  • Tuneew I [1]

Author by ORCID

  • Latorraca NR [24]
  • Kobilka BK [16]
  • O'brien ES [12]
  • Marqusee S [11]
  • Xu J [11]
  • Krishna Kumar K [11]
  • Isacoff EY [11]
  • Dror RO [8]
  • Hollingsworth SA [7]
  • Skiniotis G [6]
  • Hilger D [5]
  • Zhang Y [4]
  • Kato HE [3]
  • Weis WI [3]
  • Maeda S [3]
  • Suomivuori CM [2]
  • Schertler GFX [2]
  • Huang W [2]
  • Fonseca R [2]
  • Dawson R [2]
  • Robertson MJ [2]
  • Banister SD [1]

Journal

  • NATURE [23]
  • BIORXIV [4]
  • CELL [2]

Software

  • RELION [4]
  • FREALIGN [2]
  • CISTEM [1]
  • GCTF [1]

Microscope

  • FEI TITAN KRIOS [25]

Electron Source

  • FIELD EMISSION GUN [25]

Film or detector model

  • GATAN K3 BIOQUANTUM 6K X 4K [11]
  • GATAN K2 QUANTUM 4K X 4K [8]
  • GATAN K2 SUMMIT 4K X 4K [5]
  • GATAN K3 6K X 4K [1]

External links

  • PDB [15]
  • UniProt [15]
  • AlphaFold DB [11]
  • Gene Ontology [11]
  • InterPro [11]
  • PDBe-Kb [11]
  • Pfam [11]
  • ChEBI [6]
  • ChEMBL [6]
  • DrugBank [6]
  • CATH [3]
  • EMPIAR [1]