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author:"Burczynski ME"

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Current Database

  • EMDB [3]

Current status

  • REL [3]

Sample type

  • Complex [3]
  • Protein [3]
  • Ligand [2]

Organism

  • Homo sapiens [3]
  • Mus musculus [2]

EM Method

  • Single-particle [3]

Resolution

  • ≥ 3Å and < 4Å [3]

Model molecular weight

  • 100-250 kDa [3]

Release Date

  • 2025 [1]
  • 2024 [2]

Author by name

  • Burczynski ME [3]
  • Franklin MC [3]
  • Kim JH [3]
  • Murphy AJ [3]
  • Olson W [3]
  • Baras A [2]
  • Botermans W [2]
  • Chalasani N [2]
  • De T [2]
  • Devalaraja-narashimha KB [2]
  • Dunn ME [2]
  • Garnova E [2]
  • Herman G [2]
  • Ho AJ [2]
  • Huang T [2]
  • Jasewicz D [2]
  • Jin X [2]
  • Kamat V [2]
  • Karnik S [2]
  • Kithcart A [2]
  • Liu N [2]
  • Locke A [2]
  • Lotta LA [2]
  • Mastaitis J [2]
  • Melander O [2]
  • Meyer J [2]
  • Morton L [2]
  • Musser BJ [2]
  • Nielsen JB [2]
  • Olenchock BA [2]
  • Pan H [2]
  • Pandit A [2]
  • Rafique A [2]
  • Rankin AJ [2]
  • Romero Hernandez A [2]
  • Rosconi M [2]
  • Schwantes-an TH [2]
  • Torello J [2]
  • Verweij N [2]
  • Yancopoulos GD [2]
  • Zhang D [2]
  • Zheng W [2]
  • De Hoon J [2]
  • Chin HF [1]
  • Crowell B [1]
  • Das NM [1]
  • Economides AN [1]
  • Farrelly L [1]
  • Flanagan JJ [1]
  • Franklin M [1]
  • Harari OA [1]
  • Hassan HE [1]
  • Hatsell SJ [1]
  • Idone V [1]
  • Ivanova L [1]
  • Karayusuf E [1]
  • Kim HJ [1]
  • Kravets L [1]
  • Labriola-tompkins E [1]
  • Lob HE [1]
  • Mohammadi K [1]
  • Nannuru KC [1]
  • Perlee L [1]
  • Preda M [1]
  • Ray Y [1]
  • Retter MW [1]
  • Rottey S [1]
  • Saotome K [1]
  • Singh N [1]
  • Spencer Noakes L [1]
  • Van Lancker G [1]

Author by ORCID

  • Locke A [2]
  • Melander O [2]
  • Romero Hernandez A [2]
  • Baras A [2]
  • Lotta LA [2]
  • Devalaraja-narashimha KB [2]
  • Mastaitis J [2]
  • Murphy AJ [2]
  • Yancopoulos GD [2]
  • Meyer J [2]
  • Pan H [2]

Journal

  • NATURE [2]
  • ACTA CRYSTALLOGR D STRUCT BIOL [1]
  • JCI INSIGHT [1]

Software

  • CRYOSPARC [2]

Microscope

  • FEI TITAN KRIOS [2]
  • TFS KRIOS [1]

Electron Source

  • FIELD EMISSION GUN [3]

Film or detector model

  • GATAN K3 BIOQUANTUM 6K X 4K [3]

External links

  • AlphaFold DB [3]
  • PDB [3]
  • PDBe-Kb [3]
  • Pfam [3]
  • UniProt [3]
  • ChEBI [2]
  • ChEMBL [2]
  • Complex Portal [2]
  • Gene Ontology [2]
  • InterPro [2]
  • DrugBank [1]
Sort by: Download
Showing 1 - 3 of 3. Page 1 of 1
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EMD-49728
Download Map
3D View
TMPRSS6 in complex with REGN7999 Fab and REGN8023 Fab
Release date: July 9, 2025
Resolution: 3.29 Å
EM Method: Single-particle
Fitted PDBs: 9nrc
Q-score: 0.489

Lob HE, Singh N, Mohammadi K, Ivanova L, Crowell B, Kim HJ, Kravets L, Das NM, Ray Y, Kim JH, Rottey S, Labriola-Tompkins E, Hassan HE, Farrelly L, Chin HF, Preda M, Spencer Noakes L, Saotome K, Franklin M, Retter MW, Karayusuf E, Flanagan JJ, Olson W, Nannuru KC, Idone V, Burczynski ME, Harari OA, Perlee L, Van Lancker G, Murphy AJ, Economides AN, Hatsell SJ

JCI Insight (2025) 10 [ DOI: doi:10.1172/jci.insight.191813 Pubmed: 40548380 ]

EMD-41233
Download Map
3D View
Complex of NPR1 ectodomain with ANP plus an allosteric activating antibody, REGN5381
Release date: July 17, 2024
Resolution: 3.08 Å
EM Method: Single-particle
Fitted PDBs: 8tg9
Q-score: 0.495

Dunn ME, Kithcart A, Kim JH, Ho AJ, Franklin MC, Romero Hernandez A, de Hoon J, Botermans W, Meyer J, Jin X, Zhang D, Torello J, Jasewicz D, Kamat V, Garnova E, Liu N, Rosconi M, Pan H, Karnik S, Burczynski ME, Zheng W, Rafique A, Nielsen JB, De T, Verweij N, Pandit A, Locke A, Chalasani N, Melander O, Schwantes-An TH, Baras A, Lotta LA, Musser BJ, Mastaitis J, Devalaraja-Narashimha KB, Rankin AJ, Huang T, Herman G, Olson W, Murphy AJ, Yancopoulos GD, Olenchock BA, Morton L

Nature (2024) 633 pp. 654-661 [ Pubmed: 39261724 DOI: doi:10.1038/s41586-024-07903-1 ]

EMD-41234
Download Map
3D View
Complex of NPR1 ectodomain and REGN5381 Fab in an active-like state with no ANP bound
Release date: July 17, 2024
Resolution: 3.65 Å
EM Method: Single-particle
Fitted PDBs: 8tga
Q-score: 0.117

Dunn ME, Kithcart A, Kim JH, Ho AJ, Franklin MC, Romero Hernandez A, de Hoon J, Botermans W, Meyer J, Jin X, Zhang D, Torello J, Jasewicz D, Kamat V, Garnova E, Liu N, Rosconi M, Pan H, Karnik S, Burczynski ME, Zheng W, Rafique A, Nielsen JB, De T, Verweij N, Pandit A, Locke A, Chalasani N, Melander O, Schwantes-An TH, Baras A, Lotta LA, Musser BJ, Mastaitis J, Devalaraja-Narashimha KB, Rankin AJ, Huang T, Herman G, Olson W, Murphy AJ, Yancopoulos GD, Olenchock BA, Morton L

Nature (2024) 633 pp. 654-661 [ Pubmed: 39261724 DOI: doi:10.1038/s41586-024-07903-1 ]

Sort by: Download
Showing 1 - 3 of 3. Page 1 of 1
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [3]

Current status

  • REL [3]

Sample type

  • Complex [3]
  • Protein [3]
  • Ligand [2]

Organism

  • Homo sapiens [3]
  • Mus musculus [2]

EM Method

  • Single-particle [3]

Resolution

  • ≥ 3Å and < 4Å [3]

Model molecular weight

  • 100-250 kDa [3]

Release Date

  • 2025 [1]
  • 2024 [2]

Author by name

  • Burczynski ME [3]
  • Franklin MC [3]
  • Kim JH [3]
  • Murphy AJ [3]
  • Olson W [3]
  • Baras A [2]
  • Botermans W [2]
  • Chalasani N [2]
  • De T [2]
  • Devalaraja-narashimha KB [2]
  • Dunn ME [2]
  • Garnova E [2]
  • Herman G [2]
  • Ho AJ [2]
  • Huang T [2]
  • Jasewicz D [2]
  • Jin X [2]
  • Kamat V [2]
  • Karnik S [2]
  • Kithcart A [2]
  • Liu N [2]
  • Locke A [2]
  • Lotta LA [2]
  • Mastaitis J [2]
  • Melander O [2]
  • Meyer J [2]
  • Morton L [2]
  • Musser BJ [2]
  • Nielsen JB [2]
  • Olenchock BA [2]
  • Pan H [2]
  • Pandit A [2]
  • Rafique A [2]
  • Rankin AJ [2]
  • Romero Hernandez A [2]
  • Rosconi M [2]
  • Schwantes-an TH [2]
  • Torello J [2]
  • Verweij N [2]
  • Yancopoulos GD [2]
  • Zhang D [2]
  • Zheng W [2]
  • De Hoon J [2]
  • Chin HF [1]
  • Crowell B [1]
  • Das NM [1]
  • Economides AN [1]
  • Farrelly L [1]
  • Flanagan JJ [1]
  • Franklin M [1]
  • Harari OA [1]
  • Hassan HE [1]
  • Hatsell SJ [1]
  • Idone V [1]
  • Ivanova L [1]
  • Karayusuf E [1]
  • Kim HJ [1]
  • Kravets L [1]
  • Labriola-tompkins E [1]
  • Lob HE [1]
  • Mohammadi K [1]
  • Nannuru KC [1]
  • Perlee L [1]
  • Preda M [1]
  • Ray Y [1]
  • Retter MW [1]
  • Rottey S [1]
  • Saotome K [1]
  • Singh N [1]
  • Spencer Noakes L [1]
  • Van Lancker G [1]

Author by ORCID

  • Locke A [2]
  • Melander O [2]
  • Romero Hernandez A [2]
  • Baras A [2]
  • Lotta LA [2]
  • Devalaraja-narashimha KB [2]
  • Mastaitis J [2]
  • Murphy AJ [2]
  • Yancopoulos GD [2]
  • Meyer J [2]
  • Pan H [2]

Journal

  • NATURE [2]
  • ACTA CRYSTALLOGR D STRUCT BIOL [1]
  • JCI INSIGHT [1]

Software

  • CRYOSPARC [2]

Microscope

  • FEI TITAN KRIOS [2]
  • TFS KRIOS [1]

Electron Source

  • FIELD EMISSION GUN [3]

Film or detector model

  • GATAN K3 BIOQUANTUM 6K X 4K [3]

External links

  • AlphaFold DB [3]
  • PDB [3]
  • PDBe-Kb [3]
  • Pfam [3]
  • UniProt [3]
  • ChEBI [2]
  • ChEMBL [2]
  • Complex Portal [2]
  • Gene Ontology [2]
  • InterPro [2]
  • DrugBank [1]