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SXT
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Release date: Feb. 12, 2026
Dataset size: 90.1 GB
Experiment type: SXT

Iglesias-Fernandez M, Pérez-Berná AJ, Pereiro E, Espanol Pons M, Ginebra Molins MP

Nat Commun (2026)

Image sets:
  • Synthcrotron Cryo Soft X-ray Archives for the article "Synchrotron cryo-soft X-ray microscopy sheds light on the interaction of bacteria with nanostructured calcium phosphate substrates"
Release date: Oct. 28, 2025
Dataset size: 3.0 TB
Experiment type: SXT

Brewer J

To Be Published

Image sets:
  • Unaligned multi-frame micrographs of promoter escape by Mycobacterium tuberculosis RNAP
Release date: Sept. 16, 2025
Dataset size: 3.4 GB
Experiment type: SXT

Castro V, Calvo G, Perez-Berna AJ, Mamprin K, Kapishnikov S, Rogers D, O'Connor S, Sheridan P, Fahy K, Pereiro E, Gastaminza P

Structure (2025) 33 pp. 1547-1564 [ DOI: 10.1016/j.str.2025.05.015 Pubmed: 40553718 ]

Image sets:
  • Rapid Hepatitis C Virus Replication Machinery Removal After Antiviral 1 Treatment with DAA Monitored By Multimodal Imaging
Release date: April 7, 2025
Dataset size: 43.9 GB
Experiment type: SXT

Bolitho EM, Sanchez-Cano C, Shi H, Quinn PD, Harkiolaki M, Imberti C, Sadler PJ

Journal of the American Chemical Society (2021) 143 pp. 20224-20240 [ DOI: 10.1021/jacs.1c08630 Pubmed: 34808054 ]

Image sets:
  • Tomogram 9 (T9) - Tilt series of cryopreserved PC3 cell grown on Quantifoil TEM grids treated with 1x photo IC50 of Pt2 for 2 h (protected from light)
  • Tomogram 10 (T10) - Tilt series of cryopreserved PC3 cell grown on Quantifoil TEM grids treated with 0.25x photo IC50 of Pt2 for 1 h followed by 1 irradiation (blue light, λ=465 nm)
  • Tomogram 1 (T1) - Tilt series of cryopreserved PC3 cell grown on Quantifoil TEM grids exposed to dark conditions for 2 h
  • Tomogram 4 (T4) - Tilt series of cryopreserved PC3 cell grown on Quantifoil TEM grids exposed to 1 h irradiation (blue light, λ=465 nm)
  • Tomogram 6 (T6) - Tilt series of cryopreserved PC3 cell grown on Quantifoil TEM grids exposed to 1 h irradiation (blue light, λ=465 nm)
  • Tomogram 11 (T11) - Tilt series of cryopreserved PC3 cell grown on Quantifoil TEM grids treated with 0.25x photo IC50 of Pt2 for 1 h followed by 1 irradiation (blue light, λ=465 nm)
  • Tomogram 2 (T2) - Tilt series of cryopreserved PC3 cell grown on Quantifoil TEM grids exposed to dark conditions for 2 h
  • Tomogram 17 (T17) - Tilt series of cryopreserved PC3 cell grown on Quantifoil TEM grids treated with 1x photo IC50 of Pt2 for 1 h followed by 1 irradiation (blue light, λ=465 nm)
  • Tomogram 8 (T8) - Tilt series of cryopreserved PC3 cell grown on Quantifoil TEM grids treated with 1x photo IC50 of Pt2 for 2 h (protected from light)
  • Tomogram 7 (T7) - Tilt series of cryopreserved PC3 cell grown on Quantifoil TEM grids treated with 1x photo IC50 of Pt2 for 2 h (protected from light)
  • Tomogram 14 (T14) - Tilt series of cryopreserved PC3 cell grown on Quantifoil TEM grids treated with 0.5x photo IC50 of Pt2 for 1 h followed by 1 irradiation (blue light, λ=465 nm)
  • Tomogram 12 (T12) - Tilt series of cryopreserved PC3 cell grown on Quantifoil TEM grids treated with 0.25x photo IC50 of Pt2 for 1 h followed by 1 irradiation (blue light, λ=465 nm)
  • Tomogram 15 (T15) - Tilt series of cryopreserved PC3 cell grown on Quantifoil TEM grids treated with 1x photo IC50 of Pt2 for 1 h followed by 1 irradiation (blue light, λ=465 nm)
  • Tomogram 16 (T16) - Tilt series of cryopreserved PC3 cell grown on Quantifoil TEM grids treated with 1x photo IC50 of Pt2 for 1 h followed by 1 irradiation (blue light, λ=465 nm)
  • Tomogram 19 (T19) - Tilt series of cryopreserved PC3 cell grown on Quantifoil TEM grids treated with 1x photo IC50 of Pt2 for 1 h followed by 1 irradiation (blue light, λ=465 nm) and 2 h recovery in
  • Tomogram 13 (T13) - Tilt series of cryopreserved PC3 cell grown on Quantifoil TEM grids treated with 0.5x photo IC50 of Pt2 for 1 h followed by 1 irradiation (blue light, λ=465 nm)
  • Tomogram 5 (T5) - Tilt series of cryopreserved PC3 cell grown on Quantifoil TEM grids exposed to 1 h irradiation (blue light, λ=465 nm)
  • Tomogram 3 (T3) - Tilt series of cryopreserved PC3 cell grown on Quantifoil TEM grids exposed to dark conditions for 2 h
  • Tomogram 18 (T18) - Tilt series of cryopreserved PC3 cell grown on Quantifoil TEM grids treated with 1x photo IC50 of Pt2 for 1 h followed by 1 irradiation (blue light, λ=465 nm) and 2 h recovery
[Show more]
Release date: Oct. 17, 2023
Dataset size: 1.5 GB
Experiment type: SXT

Luengo I, Darrow MC, Spink MC, Sun Y, Dai W, He CY, Chiu W, Pridmore T, Ashton AW, Duke EMH, Basham M, French AP

J. Struct. Biol. (2017) 198 pp. 43-53 [ DOI: 10.1016/j.jsb.2017.02.007 Pubmed: 28246039 ]

Image sets:
  • Trypanosoma
Release date: Jan. 30, 2023
Dataset size: 23.5 GB
Experiment type: SXT

Dyhr MCA, Sadeghi M, Moynova R, Knappe C, Kepsutlu Çakmak B, Werner S, Schneider G, McNally J, Noe F, Ewers H

bioRxiv (2022) [ DOI: 10.1101/2022.05.16.492055 ]

Image sets:
  • Tomographic reconstruction of plunge-frozen CRFK cell
Release date: March 28, 2022
Dataset size: 9.9 GB
Experiment type: SXT

Nahas KLN, Connor VC, Harkiolaki M, Crump CM, Graham SC

bioRxiv (2021) [ DOI: 10.1101/2021.10.11.463900 ]

Image sets:
  • Representative cryoSXT datasets for studying changes to cellular compartments during HSV-1 infection of U2OS cells
Release date: Nov. 26, 2021
Dataset size: 10.1 GB
Experiment type: CLXM

Groen J, Palanca A, Aires A, Conesa JJ, Maestro D, Rehbein S, Harkiolaki M, Villar AV, Cortajarena AL, Pereiro E

Chem Sci (2021) 12 pp. 15090-15103 [ Pubmed: 34909150 DOI: 10.1039/d1sc04183e ]

Image sets:
  • Stitched and correlated 3D reconstruction of a NIH-3T3 cell
Release date: Nov. 8, 2021
Dataset size: 260.2 MB
Experiment type: SXT

Perez-Berna AJ, Benseny-Cases N, Rodríguez MJ, Valcarcel R, Carrascosa JL, Gastaminzab P, Pereiroa E

Acta Crystallogr D Struct Biol (2021) D77 pp. 1365-1377 [ Pubmed: 34726165 DOI: 10.1107/S2059798321009955 ]

Image sets:
  • Three-dimensional reconstruction of whole-cell volumes of control, HCV replicon-bearing cell lines and HCV replicating cells treated with different drugs by cryo-SXT
Release date: Sept. 1, 2021
Dataset size: 162.4 MB
Experiment type: SXT

Okolo CA, Kounatidis I, Groen J, Nahas KL, Balint S, Fish T, Koronfel MA, López-Cortajarena A, Dobbie I, Pereiro E, Harkiolaki M

Nat. Protoc (2021)

Image sets:
  • SXT using Lysosome and non-fluorescent Au as fiducials
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