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Current Database

  • EMDB [3393]
  • EMPIAR [40]

Current status

  • REL [3433]

Sample type

  • Complex [3148]
  • Protein [2990]
  • Ligand [2118]
  • RNA [1083]
  • DNA [935]
  • Virus [115]
  • Sample [83]
  • Cellular component [50]
  • Cell [31]
  • Other [26]

Organism

  • Homo sapiens [1198]
  • Synthetic construct [625]
  • Escherichia coli [484]
  • Saccharomyces cerevisiae [361]
  • Escherichia coli [177]
  • Severe acute respiratory syndrome coronavirus [167]
  • Saccharomyces cerevisiae [127]
  • Xenopus laevis [84]
  • Mus musculus [67]
  • Monkeypox virus [45]
  • Dna molecule [40]
  • Simian virus 40 [36]
  • Enterobacteria phage t4 [34]
  • Escherichia coli [32]
  • Influenza a virus [28]
  • Drosophila melanogaster [28]
  • Escherichia virus t7 [27]
  • Saccharolobus solfataricus [26]
  • Influenza a virus [25]
  • Pseudomonas phage jbd30 [24]
  • Saccharomyces cerevisiae [24]
  • Staphylococcus aureus [23]
  • Nipah virus [23]
  • Thermococcus kodakarensis [21]
  • Human herpesvirus 1 [20]
  • Human immunodeficiency virus 1 [20]
  • Influenza a virus [20]
  • Human herpesvirus 1 [18]
  • Influenza b virus [18]
  • Camelidae mixed library [17]
  • Chikungunya virus [16]
  • Escherichia coli [15]
  • Mammalian orthoreovirus [14]
  • Influenza b virus [14]
  • Foot-and-mouth disease virus [14]
  • Apis mellifera [14]
  • Sus scrofa [14]
  • Adeno-associated dependoparvovirus a [13]
  • Simplexvirus humanalpha1 [13]
  • Escherichia coli [13]
  • Lassa mammarenavirus [12]
  • Machupo virus [12]
  • Pyrococcus furiosus [12]
  • Photorhabdus thracensis [12]
  • Chikungunya virus [12]
  • Spodoptera frugiperda [12]
  • African swine fever virus [11]
  • Unidentified adenovirus [11]
  • Enterobacteria phage t4 [11]
  • Tetrahymena thermophila [11]
  • Bos taurus [11]
  • Human herpesvirus 1 [10]
  • Thogotovirus thogotoense [10]
  • Escherichia phage mu [10]
  • Pyrococcus abyssi [10]
  • Chaetomium thermophilum [10]
  • Influenza a virus [9]
  • Hantaan orthohantavirus [9]
  • Flock house virus [9]
  • Escherichia coli [9]
  • (no species) [8]
  • Simian virus 40 [8]
  • Mycolicibacterium thermoresistibile [8]
  • Pseudomonas phage phi6 [8]
  • Bacillus subtilis [8]
  • Influenza a virus [8]
  • Dictyostelium discoideum [8]
  • Escherichia coli [8]
  • Plasmodium falciparum [8]
  • Caenorhabditis elegans [8]
  • Sus scrofa [8]
  • Mycobacterium tuberculosis [7]
  • Schizosaccharomyces pombe [7]
  • Pyrococcus abyssi [7]
  • Gallus gallus [7]
  • Influenza c virus [6]
  • Bovine papillomavirus [6]
  • Cypovirus 1 [6]
  • La crosse orthobunyavirus [6]
  • Human immunodeficiency virus 2 [6]
  • Saccharomyces cerevisiae [6]
  • Middle east respiratory syndrome-related coronavirus [6]
  • Emiliania huxleyi virus 201 [6]
  • Human respiratory syncytial virus [6]
  • La crosse orthobunyavirus [6]
  • Torbevirus viento [6]
  • Influenza a virus [6]
  • Mammalian orthoreovirus [6]
  • Vibrio alginolyticus [6]
  • Oryctolagus cuniculus [6]
  • Pseudomonas putida [5]
  • (no species) [5]
  • Methanosarcina mazei [5]
  • Hantaan orthohantavirus [5]
  • Synthetic rna [5]
  • Tomato spotted wilt virus [5]
  • Rotavirus a [5]
  • Schizosaccharomyces pombe [5]
  • Komagataella phaffii [5]
  • Sfts phlebovirus [5]

EM Method

  • Single-particle [3242]
  • Helical reconstruction [70]
  • Subtomogram averaging [53]
  • Tomography [22]
  • Electron Crystallography [6]

Resolution

  • < 2Å [24]
  • ≥ 2Å and < 3Å [899]
  • ≥ 3Å and < 4Å [1658]
  • ≥ 4Å and < 5Å [373]
  • ≥ 5Å and < 6Å [73]
  • ≥ 6Å and < 8Å [122]
  • ≥ 8Å and < 12Å [88]
  • ≥ 12Å and < 16Å [30]
  • ≥ 16Å and < 20Å [39]
  • ≥ 20Å and < 30Å [40]
  • ≥ 30Å [26]

Model molecular weight

  • 0-50 kDa [8]
  • 50-100 kDa [60]
  • 100-250 kDa [503]
  • 250-500 kDa [895]
  • 500-1000 kDa [478]
  • 1-2 MDa [322]
  • 2-5 MDa [542]
  • 5-10 MDa [8]
  • > 10 MDa [18]

Release Date

  • 2026 [466]
  • 2025 [660]
  • 2024 [569]
  • 2023 [492]
  • 2022 [325]
  • 2021 [304]
  • 2020 [265]
  • 2019 [121]
  • 2018 [63]
  • 2017 [53]
  • 2016 [42]
  • 2015 [22]
  • 2014 [9]
  • 2013 [8]
  • 2012 [9]
  • 2011 [12]
  • 2010 [1]
  • 2009 [3]
  • 2007 [3]
  • 2006 [5]
  • 2005 [1]

Author by name

  • Li H [149]
  • Zhang Y [132]
  • Zhang X [108]
  • Gao Y [107]
  • Wang X [90]
  • Wang C [89]
  • Cusack S [83]
  • Shi Y [82]
  • Yeeles JTP [82]
  • Zhang Z [81]
  • O Donnell Me [76]
  • Zhou ZH [75]
  • Liu Y [74]
  • Korostelev AA [70]
  • Demo G [68]
  • Wang Y [67]
  • Wang J [66]
  • Zhang J [66]
  • Costa A [63]
  • Li Y [62]
  • Wang H [61]
  • Loveland AB [59]
  • Speck C [59]
  • Yu Z [59]
  • Li M [58]
  • Grimes JM [57]
  • Carrique L [56]
  • Li N [56]
  • Jones ML [55]
  • Arragain B [54]
  • Fodor E [54]
  • Gao N [54]
  • Keown JR [54]
  • Li J [54]
  • Li S [54]
  • Rao Z [54]
  • Georgescu R [53]
  • Wang M [53]
  • Ebright RH [52]
  • Li Q [52]
  • Beckmann R [51]
  • Baris Y [50]
  • De Biasio A [50]
  • Hamdan SM [50]
  • Liu B [50]
  • Noguchi Y [50]
  • Tehseen M [50]
  • Wilson DN [50]
  • Larsson DSD [49]
  • Selmer M [49]
  • Wang Q [49]
  • Aramayo R [48]
  • Liu Z [48]
  • Novacek J [48]
  • Ivanova ME [47]
  • Li Z [47]
  • Saleh A [47]
  • Xu C [47]
  • Yang J [47]
  • Yao NY [47]
  • Chen J [46]
  • Lu Y [46]
  • Zhang K [46]
  • Zhang L [46]
  • Blaha G [45]
  • Chen X [45]
  • He Q [45]
  • Savva CG [45]
  • Cheng J [44]
  • Kaelber JT [43]
  • Liu X [43]
  • Rodnina MV [43]
  • Fraser JS [42]
  • Molodtsov V [42]
  • Qi J [42]
  • Wang F [42]
  • Li W [41]
  • Shahid T [41]
  • Xie Y [41]
  • Berninghausen O [40]
  • Xu Y [40]
  • Yan L [40]
  • Gao GF [39]
  • Huang Y [39]
  • Li B [39]
  • Danazumi AU [38]
  • Drncova P [38]
  • Fan H [38]
  • Liu Q [38]
  • Lou Z [38]
  • Pavletich NP [38]
  • Remme J [38]
  • Spahn CMT [38]
  • Wang L [38]
  • Yuan Z [38]
  • Zhao X [38]
  • Cui Y [37]
  • Liu C [37]
  • Alhudhali L [36]
  • Clark AR [36]

Author by ORCID

  • Li H [55]
  • Larsson DSD [49]
  • Selmer M [48]
  • Hamdan SM [47]
  • Speck C [47]
  • Cusack S [47]
  • Keown JR [45]
  • Fodor E [41]
  • De Biasio A [40]
  • Arragain B [39]
  • Zhou ZH [39]
  • O'donnell ME [37]
  • Fraser JS [37]
  • Yeeles JTP [36]
  • Shahid T [34]
  • Danazumi AU [34]
  • Remus D [32]
  • Hite RK [32]
  • Hou YM [30]
  • Shi Y [28]
  • Pavletich NP [27]
  • Pellegrino J [27]
  • Seiple IB [27]
  • Rodnina MV [27]
  • Korostelev AA [27]
  • Jones ML [27]
  • Myasnikov A [26]
  • Novacek J [26]
  • Grimes JM [25]
  • Skwark MJ [25]
  • Gao GF [25]
  • Montoya A [25]
  • Aramayo R [25]
  • Jenkyn-bedford M [25]
  • Wilson DN [25]
  • Sunidhi S [25]
  • Li B [25]
  • Klinge S [24]
  • Vanden Broeck A [24]
  • Zhang P [24]
  • Naffakh N [23]
  • Spahn CMT [23]
  • Qi J [23]
  • Krischuns T [23]
  • Allwein B [22]
  • Bruning JG [22]
  • Batra S [22]
  • Lee CM [22]
  • Xie Y [21]
  • Pardon E [21]
  • Steyaert J [21]
  • Tahirov TH [20]
  • Chen ZA [20]
  • Ubarretxena-belandia I [20]
  • Beckmann R [20]
  • Rappsilber J [19]
  • Saleh A [19]
  • He Q [19]
  • Eichman BF [19]
  • Tognetti S [19]
  • He J [19]
  • Lim CJ [19]
  • Mullins EA [19]
  • Carrique L [18]
  • Ye M [18]
  • Gilbert RJC [18]
  • Deegan TD [18]
  • Wang D [18]
  • Li M [18]
  • Lu Y [18]
  • Li Q [18]
  • Sheng Y [18]
  • Enemark EJ [18]
  • Rasouli S [18]
  • Yi G [18]
  • Chazin WJ [17]
  • Lee DJ [17]
  • Demo G [17]
  • Shen PS [17]
  • Blackledge M [17]
  • Costa A [17]
  • Lopez-alonso JP [17]
  • Tascon I [17]
  • Tian WX [16]
  • Liu B [16]
  • Fuzik T [16]
  • He Y [16]
  • Liu B [16]
  • Zhai Y [16]
  • Gao N [16]
  • Feigon J [16]
  • Lauer SM [16]
  • Plevka P [16]
  • Gil-carton D [16]
  • Nikolay R [16]
  • Salay LE [15]
  • Dang S [15]
  • Loveland AB [15]
  • Zhang X [15]
  • Georgescu R [15]

Journal

  • NAT COMMUN [806]
  • NATURE [342]
  • NAT STRUCT MOL BIOL [286]
  • BIORXIV [250]
  • SCIENCE [238]
  • TO BE PUBLISHED [223]
  • NUCLEIC ACIDS RES [197]
  • MOL CELL [177]
  • PNAS [141]
  • CELL [124]
  • ELIFE [101]
  • SCI ADV [84]
  • EMBO J [72]
  • CELL RES [55]
  • CELL REP [50]
  • J BIOL CHEM [46]
  • J MOL BIOL [37]
  • ACTA CRYSTALLOGR D STRUCT BIOL [30]
  • CELL DISCOV [30]
  • NAT CHEM BIOL [30]
  • NAT MICROBIOL [23]
  • STRUCTURE [23]
  • COMMUN BIOL [19]
  • ISCIENCE [18]
  • EMBO REP [17]
  • PLOS PATHOG [15]
  • J VIROL [14]
  • INT J MOL SCI [13]
  • PROTEIN CELL [10]
  • SCI REP [10]
  • GENET MED [9]
  • NAT PLANTS [9]
  • J AM CHEM SOC [8]
  • SCI BULL (BEIJING) [8]
  • FEBS OPEN BIO [7]
  • RES SQ [7]
  • COMMUN CHEM [6]
  • DIS MODEL MECH [6]
  • J MED CHEM [6]
  • ADV SCI [5]
  • MBIO [5]
  • NPJ VACCINES [5]
  • PLOS NEGL TROP DIS [5]
  • CELL DEATH DIFFER. [4]
  • J CELL BIOL [4]
  • NAT CATAL [4]
  • PROTEIN SCI [4]
  • RNA [4]
  • ACS CENT SCI [3]
  • CELL HOST MICROBE [3]
  • INT J BIOL MACROMOL [3]
  • NAT CHEM [3]
  • NAT METHODS [3]
  • PNAS NEXUS [3]
  • VIRUSES [3]
  • ACS INFECT DIS. [2]
  • BIOCHEM J [2]
  • CELL CHEM BIOL [2]
  • CELL REP PHYS SCI [2]
  • FRONT MICROBIOL [2]
  • IUCRJ [2]
  • J MOL CELL BIOL [2]
  • J.BIOCHEM. [2]
  • PHILOS.TRANS.R.SOC.LOND.B BIOL.SCI. [2]
  • ACS CENTRAL SCIENCE [1]
  • ACS MED.CHEM.LETT. [1]
  • BBA ADV [1]
  • BIOMOLECULES [1]
  • CANCER DISCOV [1]
  • COMMUNICATIONS BIOLOGY [1]
  • CURR BIOL [1]
  • DEV CELL [1]
  • EBIOMEDICINE [1]
  • EUR.J.MED.CHEM. [1]
  • INNOVATION (NY) [1]
  • J CELL SCI [1]
  • J STRUCT BIOL [1]
  • J STRUCT BIOL X [1]
  • METHODS [1]
  • NAT CELL BIOL [1]
  • PLOS BIOL [1]
  • PLOS ONE [1]
  • PROTEINS [1]
  • SOIL BIOL.BIOCHEM. [1]
  • VACCINES (BASEL) [1]
  • VITA [1]

Software

  • CRYOSPARC [1096]
  • RELION [979]
  • CTFFIND [168]
  • GCTF [127]
  • FREALIGN [62]
  • CISTEM [56]
  • COOT [39]
  • UCSF CHIMERA [22]
  • CHIMERA [20]
  • DYNAMO [20]
  • WARP [18]
  • SPIDER [17]
  • PHENIX [16]
  • UCSF CHIMERAX [16]
  • EMCLARITY [11]
  • IMOD [9]
  • XMIPP [9]
  • CRYOLO [8]
  • CTFPHASEFLIP [6]
  • EMAN2, SPARX [5]
  • EMREADY [5]
  • ISOLDE [5]
  • MOTIONCORR2 [5]
  • SPIDER XMIPP [5]
  • EMAN [4]
  • EMAN2 [4]
  • IMAGIC [4]
  • SPARX [4]
  • EMAN, XMIPP [3]
  • IMAGIC, CTFIT, CTFFIND3 [3]
  • PEET [3]
  • RELION, CTFFIND3, EMAN2 [3]
  • RELION1.3 [3]
  • RELION_1.4 [3]
  • SERIALEM [3]
  • XMIPP, IMAGIC, SPIDER, APPION, CTFFIND3 [3]
  • BSOFT [2]
  • EMAN2, RELION [2]
  • IMAGIC-5 [2]
  • IMIRS [2]
  • RELION1.4 [2]
  • RELION_1.3 [2]
  • ADPEM [1]
  • CCP4 PACKAGE [1]
  • CHIMERA, VEDA [1]
  • CRYO [1]
  • CTFFIND3 [1]
  • EMAN, IMAGIC [1]
  • EMAN, SPIDER [1]
  • EMAN,IMAGIC [1]
  • EMIP, CHIMERA [1]
  • ETOMO [1]
  • GAUTOMATCH [1]
  • I3 [1]
  • IHRSR, XMIPP, IMAGIC, SPIDER, APPION, CTFFIND3 [1]
  • IMAGIC, RICO, BSOFT, CTFFIND3, FPM [1]
  • IMAGIC, SPIDER [1]
  • MATLAB [1]
  • MATLAB, IMAGEV [1]
  • MDFF METHOD [1]
  • MODELLER, CHIMERA, PHENIX, COOT [1]
  • MRC, EMIP, CHIMERA [1]
  • O [1]
  • SPDER [1]
  • SPIDER, EMAN [1]
  • SPIDER, RELION [1]
  • SPRING [1]
  • URO [1]
  • VEDA [1]
  • XMIPP AND EMAN [1]
  • XMIPP, EMAN2, SPIDER [1]

Microscope

  • FEI TITAN KRIOS [1894]
  • TFS KRIOS [1033]
  • FEI TALOS ARCTICA [136]
  • TFS GLACIOS [106]
  • FEI POLARA 300 [39]
  • FEI TECNAI F20 [25]
  • FEI TECNAI ARCTICA [23]
  • FEI TITAN [17]
  • FEI TECNAI F30 [16]
  • FEI TECNAI 20 [15]
  • FEI TECNAI 12 [14]
  • TFS TALOS [14]
  • TFS TALOS F200C [12]
  • JEOL CRYO ARM 300 [8]
  • JEOL 2000EX [5]
  • JEOL 2200FS [5]
  • JEOL CRYO ARM 200 [4]
  • JEOL 1230 [3]
  • JEOL 2010F [3]
  • JEOL 2100 [3]
  • JEOL 3200FS [3]
  • FEI TECNAI SPIRIT [2]
  • FEI/PHILIPS CM200FEG [2]
  • JEOL 1010 [2]
  • JEOL 1200EX [2]
  • JEOL 1200EXII [2]
  • JEOL 1400/HR YPS FEG [2]
  • FEI MORGAGNI [1]
  • FEI/PHILIPS CM300FEG/T [1]
  • JEOL 2100F [1]
  • JEOL 3200FSC [1]

Electron Source

  • FIELD EMISSION GUN [3333]
  • LAB6 [33]
  • TUNGSTEN HAIRPIN [19]
  • OTHER [8]

Film or detector model

  • GATAN K3 6K X 4K [1029]
  • GATAN K3 BIOQUANTUM 6K X 4K [754]
  • GATAN K2 SUMMIT 4K X 4K [716]
  • FEI FALCON IV 4K X 4K [259]
  • FEI FALCON III 4K X 4K [205]
  • GATAN K2 QUANTUM 4K X 4K [123]
  • TFS FALCON 4I 4K X 4K [100]
  • FEI FALCON II 4K X 4K [73]
  • GATAN K3 BIOCONTINUUM 6K X 4K [34]
  • KODAK SO-163 FILM [25]
  • GATAN ULTRASCAN 4000 4K X 4K [21]
  • TVIPS TEMCAM-F416 4K X 4K [12]
  • FEI CETA 4K X 4K [9]
  • GATAN K2 BASE 4K X 4K [6]
  • GENERIC GATAN [6]
  • GENERIC CCD [4]
  • GATAN K2 4K X 4K [3]
  • OTHER [3]
  • DECTRIS SINGLA 1K X 1K [2]
  • DIRECT ELECTRON DE-16 4K X 4K [2]
  • FEI EAGLE 4K X 4K [2]
  • GENERIC TVIPS 4K X 4K [2]
  • TVIPS TEMCAM-F415 4K X 4K [2]
  • DIRECT ELECTRON DE-64 8K X 8K [1]
  • FEI FALCON I 4K X 4K [1]
  • GATAN K2 IS 4K X 4K [1]
  • GATAN ULTRASCAN 1000 2K X 2K [1]
  • GENERIC GATAN 4K X 4K [1]
  • GENERIC TVIPS [1]

EMPIAR Experiment type

  • EMDB [32]
  • CLEM [6]
  • SXT [2]

EMPIAR Image category

  • MICROGRAPHS - MULTIFRAME [31]
  • MICROGRAPHS - SINGLE FRAME [12]
  • RECONSTRUCTED VOLUMES [3]
  • TILT SERIES [3]
  • PICKED PARTICLES - SINGLE FRAME - PROCESSED [2]

External links

  • UniProt [2882]
  • PDB [2842]
  • PDBe-Kb [2732]
  • Gene Ontology [2675]
  • InterPro [2576]
  • AlphaFold DB [2491]
  • Pfam [2442]
  • ChEBI [2013]
  • DrugBank [1975]
  • ChEMBL [1881]
  • Complex Portal [1486]
  • EMPIAR [407]
  • SCOP2 [42]
  • CATH [33]
  • EMDB [32]
  • BioImage Archive [6]
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EMD-55567
Download Map
3D View
Structure of the Vesicular Stomatitis Virus L Protein in Complex with the Phosphoprotein and the Nucleoprotein
CryoEM
Release date: Oct. 7, 2026
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 9t53
Q-score: 0.278
Similar entry percentile: 12%

Bloyet LM, Whelan SPJ

To Be Published

EMD-71503
Download Map
3D View
Human DNA Polymerase Gamma-RNA-DNA Primer-Template Complex with Incoming ATP
CryoEM
Release date: Oct. 7, 2026
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 9pck
Q-score: 0.458
Similar entry percentile: 17%

Sokolova V, Buchel G, Strock S, Nayak AR, Temiakov D

Nucleic Acids Res (2026) 54 [ Pubmed: 42788360 DOI: doi:10.1093/nar/gkag925 ]

EMD-76387
Download Map
3D View
EcPriA bound to DNA replication fork with dsDNA lagging strand
CryoEM
Release date: Oct. 7, 2026
Resolution: 3.5 Å
EM Method: Single-particle

Deorio HR, Duckworth AT, Forsythe GR, Sung AY, Sandler SJ, Grant T, Keck JL

Nucleic Acids Res (2026) 54 [ Pubmed: 42770332 DOI: doi:10.1093/nar/gkag911 ]

EMD-76388
Download Map
3D View
EcPriA bound to DNA replication fork with ssDNA lagging strand CRR up
CryoEM
Release date: Oct. 7, 2026
Resolution: 3.8 Å
EM Method: Single-particle

Deorio HR, Duckworth AT, Forsythe GR, Sung AY, Sandler SJ, Grant T, Keck JL

Nucleic Acids Res (2026) 54 [ Pubmed: 42770332 DOI: doi:10.1093/nar/gkag911 ]

EMD-76389
Download Map
3D View
EcPriA bound to DNA replication fork with ssDNA lagging strand CRR down
CryoEM
Release date: Oct. 7, 2026
Resolution: 3.8 Å
EM Method: Single-particle

Deorio HR, Duckworth AT, Forsythe GR, Sung AY, Sandler SJ, Grant T, Keck JL

Nucleic Acids Res (2026) 54 [ Pubmed: 42770332 DOI: doi:10.1093/nar/gkag911 ]

EMD-76732
Download Map
3D View
Structure of a Strand-Displacement Complex of Human Mitochondrial DNA Polymerase Gamma
Composite map
CryoEM
Release date: Oct. 7, 2026
Resolution: 2.93 Å
EM Method: Single-particle
Fitted PDBs: 12sl
Q-score: 0.431
Similar entry percentile: 21%

Sokolova V, Buchel G, Strock S, Nayak AR, Temiakov D

Nucleic Acids Res (2026) 54 [ Pubmed: 42788360 DOI: doi:10.1093/nar/gkag925 ]

EMD-77233
Download Map
3D View
Raw Consensus map of the Strand-Displacement Complex of Human Mitochondrial DNA Polymerase Gamma
CryoEM
Consensus map
Release date: Oct. 7, 2026
Resolution: 2.93 Å
EM Method: Single-particle

Sokolova V, Buchel G, Strock S, Nayak AR, Temiakov D

Nucleic Acids Res (2026) 54 [ Pubmed: 42788360 DOI: doi:10.1093/nar/gkag925 ]

EMD-77234
Download Map
3D View
Focused map Catalytic Subunit of the Strand-Displacement Complex of Human Mitochondrial DNA Polymerase Gamma
CryoEM
Focused map
Release date: Oct. 7, 2026
Resolution: 2.9 Å
EM Method: Single-particle

Sokolova V, Buchel G, Strock S, Nayak AR, Temiakov D

Nucleic Acids Res (2026) 54 [ Pubmed: 42788360 DOI: doi:10.1093/nar/gkag925 ]

EMD-77235
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3D View
Focused map Accessory Subunit of the Strand-Displacement Complex of Human Mitochondrial DNA Polymerase Gamma
Focused map
CryoEM
Release date: Oct. 7, 2026
Resolution: 2.81 Å
EM Method: Single-particle

Sokolova V, Buchel G, Strock S, Nayak AR, Temiakov D

Nucleic Acids Res (2026) 54 [ Pubmed: 42788360 DOI: doi:10.1093/nar/gkag925 ]

EMD-80334
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3D View
Cryo-EM structure of the E. coli beta sliding clamp-Hda heterooctamer
CryoEM
Release date: Oct. 7, 2026
Resolution: 3.12 Å
EM Method: Single-particle
Fitted PDBs: 25ry
Q-score: 0.403
Similar entry percentile: 19%

Jiang X, Danev R, Luan Y, Nakakido M, Tsumoto K, Kikkawa M

Nucleic Acids Res (2026) [ ]

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Current Database

  • EMDB [3393]
  • EMPIAR [40]

Current status

  • REL [3433]

Sample type

  • Complex [3148]
  • Protein [2990]
  • Ligand [2118]
  • RNA [1083]
  • DNA [935]
  • Virus [115]
  • Sample [83]
  • Cellular component [50]
  • Cell [31]
  • Other [26]

Organism

  • Homo sapiens [1198]
  • Synthetic construct [625]
  • Escherichia coli [484]
  • Saccharomyces cerevisiae [361]
  • Escherichia coli [177]
  • Severe acute respiratory syndrome coronavirus [167]
  • Saccharomyces cerevisiae [127]
  • Xenopus laevis [84]
  • Mus musculus [67]
  • Monkeypox virus [45]
  • Dna molecule [40]
  • Simian virus 40 [36]
  • Enterobacteria phage t4 [34]
  • Escherichia coli [32]
  • Influenza a virus [28]
  • Drosophila melanogaster [28]
  • Escherichia virus t7 [27]
  • Saccharolobus solfataricus [26]
  • Influenza a virus [25]
  • Pseudomonas phage jbd30 [24]
  • Saccharomyces cerevisiae [24]
  • Staphylococcus aureus [23]
  • Nipah virus [23]
  • Thermococcus kodakarensis [21]
  • Human herpesvirus 1 [20]
  • Human immunodeficiency virus 1 [20]
  • Influenza a virus [20]
  • Human herpesvirus 1 [18]
  • Influenza b virus [18]
  • Camelidae mixed library [17]
  • Chikungunya virus [16]
  • Escherichia coli [15]
  • Mammalian orthoreovirus [14]
  • Influenza b virus [14]
  • Foot-and-mouth disease virus [14]
  • Apis mellifera [14]
  • Sus scrofa [14]
  • Adeno-associated dependoparvovirus a [13]
  • Simplexvirus humanalpha1 [13]
  • Escherichia coli [13]
  • Lassa mammarenavirus [12]
  • Machupo virus [12]
  • Pyrococcus furiosus [12]
  • Photorhabdus thracensis [12]
  • Chikungunya virus [12]
  • Spodoptera frugiperda [12]
  • African swine fever virus [11]
  • Unidentified adenovirus [11]
  • Enterobacteria phage t4 [11]
  • Tetrahymena thermophila [11]
  • Bos taurus [11]
  • Human herpesvirus 1 [10]
  • Thogotovirus thogotoense [10]
  • Escherichia phage mu [10]
  • Pyrococcus abyssi [10]
  • Chaetomium thermophilum [10]
  • Influenza a virus [9]
  • Hantaan orthohantavirus [9]
  • Flock house virus [9]
  • Escherichia coli [9]
  • (no species) [8]
  • Simian virus 40 [8]
  • Mycolicibacterium thermoresistibile [8]
  • Pseudomonas phage phi6 [8]
  • Bacillus subtilis [8]
  • Influenza a virus [8]
  • Dictyostelium discoideum [8]
  • Escherichia coli [8]
  • Plasmodium falciparum [8]
  • Caenorhabditis elegans [8]
  • Sus scrofa [8]
  • Mycobacterium tuberculosis [7]
  • Schizosaccharomyces pombe [7]
  • Pyrococcus abyssi [7]
  • Gallus gallus [7]
  • Influenza c virus [6]
  • Bovine papillomavirus [6]
  • Cypovirus 1 [6]
  • La crosse orthobunyavirus [6]
  • Human immunodeficiency virus 2 [6]
  • Saccharomyces cerevisiae [6]
  • Middle east respiratory syndrome-related coronavirus [6]
  • Emiliania huxleyi virus 201 [6]
  • Human respiratory syncytial virus [6]
  • La crosse orthobunyavirus [6]
  • Torbevirus viento [6]
  • Influenza a virus [6]
  • Mammalian orthoreovirus [6]
  • Vibrio alginolyticus [6]
  • Oryctolagus cuniculus [6]
  • Pseudomonas putida [5]
  • (no species) [5]
  • Methanosarcina mazei [5]
  • Hantaan orthohantavirus [5]
  • Synthetic rna [5]
  • Tomato spotted wilt virus [5]
  • Rotavirus a [5]
  • Schizosaccharomyces pombe [5]
  • Komagataella phaffii [5]
  • Sfts phlebovirus [5]

EM Method

  • Single-particle [3242]
  • Helical reconstruction [70]
  • Subtomogram averaging [53]
  • Tomography [22]
  • Electron Crystallography [6]

Resolution

  • < 2Å [24]
  • ≥ 2Å and < 3Å [899]
  • ≥ 3Å and < 4Å [1658]
  • ≥ 4Å and < 5Å [373]
  • ≥ 5Å and < 6Å [73]
  • ≥ 6Å and < 8Å [122]
  • ≥ 8Å and < 12Å [88]
  • ≥ 12Å and < 16Å [30]
  • ≥ 16Å and < 20Å [39]
  • ≥ 20Å and < 30Å [40]
  • ≥ 30Å [26]

Model molecular weight

  • 0-50 kDa [8]
  • 50-100 kDa [60]
  • 100-250 kDa [503]
  • 250-500 kDa [895]
  • 500-1000 kDa [478]
  • 1-2 MDa [322]
  • 2-5 MDa [542]
  • 5-10 MDa [8]
  • > 10 MDa [18]

Release Date

  • 2026 [466]
  • 2025 [660]
  • 2024 [569]
  • 2023 [492]
  • 2022 [325]
  • 2021 [304]
  • 2020 [265]
  • 2019 [121]
  • 2018 [63]
  • 2017 [53]
  • 2016 [42]
  • 2015 [22]
  • 2014 [9]
  • 2013 [8]
  • 2012 [9]
  • 2011 [12]
  • 2010 [1]
  • 2009 [3]
  • 2007 [3]
  • 2006 [5]
  • 2005 [1]

Author by name

  • Li H [149]
  • Zhang Y [132]
  • Zhang X [108]
  • Gao Y [107]
  • Wang X [90]
  • Wang C [89]
  • Cusack S [83]
  • Shi Y [82]
  • Yeeles JTP [82]
  • Zhang Z [81]
  • O Donnell Me [76]
  • Zhou ZH [75]
  • Liu Y [74]
  • Korostelev AA [70]
  • Demo G [68]
  • Wang Y [67]
  • Wang J [66]
  • Zhang J [66]
  • Costa A [63]
  • Li Y [62]
  • Wang H [61]
  • Loveland AB [59]
  • Speck C [59]
  • Yu Z [59]
  • Li M [58]
  • Grimes JM [57]
  • Carrique L [56]
  • Li N [56]
  • Jones ML [55]
  • Arragain B [54]
  • Fodor E [54]
  • Gao N [54]
  • Keown JR [54]
  • Li J [54]
  • Li S [54]
  • Rao Z [54]
  • Georgescu R [53]
  • Wang M [53]
  • Ebright RH [52]
  • Li Q [52]
  • Beckmann R [51]
  • Baris Y [50]
  • De Biasio A [50]
  • Hamdan SM [50]
  • Liu B [50]
  • Noguchi Y [50]
  • Tehseen M [50]
  • Wilson DN [50]
  • Larsson DSD [49]
  • Selmer M [49]
  • Wang Q [49]
  • Aramayo R [48]
  • Liu Z [48]
  • Novacek J [48]
  • Ivanova ME [47]
  • Li Z [47]
  • Saleh A [47]
  • Xu C [47]
  • Yang J [47]
  • Yao NY [47]
  • Chen J [46]
  • Lu Y [46]
  • Zhang K [46]
  • Zhang L [46]
  • Blaha G [45]
  • Chen X [45]
  • He Q [45]
  • Savva CG [45]
  • Cheng J [44]
  • Kaelber JT [43]
  • Liu X [43]
  • Rodnina MV [43]
  • Fraser JS [42]
  • Molodtsov V [42]
  • Qi J [42]
  • Wang F [42]
  • Li W [41]
  • Shahid T [41]
  • Xie Y [41]
  • Berninghausen O [40]
  • Xu Y [40]
  • Yan L [40]
  • Gao GF [39]
  • Huang Y [39]
  • Li B [39]
  • Danazumi AU [38]
  • Drncova P [38]
  • Fan H [38]
  • Liu Q [38]
  • Lou Z [38]
  • Pavletich NP [38]
  • Remme J [38]
  • Spahn CMT [38]
  • Wang L [38]
  • Yuan Z [38]
  • Zhao X [38]
  • Cui Y [37]
  • Liu C [37]
  • Alhudhali L [36]
  • Clark AR [36]

Author by ORCID

  • Li H [55]
  • Larsson DSD [49]
  • Selmer M [48]
  • Hamdan SM [47]
  • Speck C [47]
  • Cusack S [47]
  • Keown JR [45]
  • Fodor E [41]
  • De Biasio A [40]
  • Arragain B [39]
  • Zhou ZH [39]
  • O'donnell ME [37]
  • Fraser JS [37]
  • Yeeles JTP [36]
  • Shahid T [34]
  • Danazumi AU [34]
  • Remus D [32]
  • Hite RK [32]
  • Hou YM [30]
  • Shi Y [28]
  • Pavletich NP [27]
  • Pellegrino J [27]
  • Seiple IB [27]
  • Rodnina MV [27]
  • Korostelev AA [27]
  • Jones ML [27]
  • Myasnikov A [26]
  • Novacek J [26]
  • Grimes JM [25]
  • Skwark MJ [25]
  • Gao GF [25]
  • Montoya A [25]
  • Aramayo R [25]
  • Jenkyn-bedford M [25]
  • Wilson DN [25]
  • Sunidhi S [25]
  • Li B [25]
  • Klinge S [24]
  • Vanden Broeck A [24]
  • Zhang P [24]
  • Naffakh N [23]
  • Spahn CMT [23]
  • Qi J [23]
  • Krischuns T [23]
  • Allwein B [22]
  • Bruning JG [22]
  • Batra S [22]
  • Lee CM [22]
  • Xie Y [21]
  • Pardon E [21]
  • Steyaert J [21]
  • Tahirov TH [20]
  • Chen ZA [20]
  • Ubarretxena-belandia I [20]
  • Beckmann R [20]
  • Rappsilber J [19]
  • Saleh A [19]
  • He Q [19]
  • Eichman BF [19]
  • Tognetti S [19]
  • He J [19]
  • Lim CJ [19]
  • Mullins EA [19]
  • Carrique L [18]
  • Ye M [18]
  • Gilbert RJC [18]
  • Deegan TD [18]
  • Wang D [18]
  • Li M [18]
  • Lu Y [18]
  • Li Q [18]
  • Sheng Y [18]
  • Enemark EJ [18]
  • Rasouli S [18]
  • Yi G [18]
  • Chazin WJ [17]
  • Lee DJ [17]
  • Demo G [17]
  • Shen PS [17]
  • Blackledge M [17]
  • Costa A [17]
  • Lopez-alonso JP [17]
  • Tascon I [17]
  • Tian WX [16]
  • Liu B [16]
  • Fuzik T [16]
  • He Y [16]
  • Liu B [16]
  • Zhai Y [16]
  • Gao N [16]
  • Feigon J [16]
  • Lauer SM [16]
  • Plevka P [16]
  • Gil-carton D [16]
  • Nikolay R [16]
  • Salay LE [15]
  • Dang S [15]
  • Loveland AB [15]
  • Zhang X [15]
  • Georgescu R [15]

Journal

  • NAT COMMUN [806]
  • NATURE [342]
  • NAT STRUCT MOL BIOL [286]
  • BIORXIV [250]
  • SCIENCE [238]
  • TO BE PUBLISHED [223]
  • NUCLEIC ACIDS RES [197]
  • MOL CELL [177]
  • PNAS [141]
  • CELL [124]
  • ELIFE [101]
  • SCI ADV [84]
  • EMBO J [72]
  • CELL RES [55]
  • CELL REP [50]
  • J BIOL CHEM [46]
  • J MOL BIOL [37]
  • ACTA CRYSTALLOGR D STRUCT BIOL [30]
  • CELL DISCOV [30]
  • NAT CHEM BIOL [30]
  • NAT MICROBIOL [23]
  • STRUCTURE [23]
  • COMMUN BIOL [19]
  • ISCIENCE [18]
  • EMBO REP [17]
  • PLOS PATHOG [15]
  • J VIROL [14]
  • INT J MOL SCI [13]
  • PROTEIN CELL [10]
  • SCI REP [10]
  • GENET MED [9]
  • NAT PLANTS [9]
  • J AM CHEM SOC [8]
  • SCI BULL (BEIJING) [8]
  • FEBS OPEN BIO [7]
  • RES SQ [7]
  • COMMUN CHEM [6]
  • DIS MODEL MECH [6]
  • J MED CHEM [6]
  • ADV SCI [5]
  • MBIO [5]
  • NPJ VACCINES [5]
  • PLOS NEGL TROP DIS [5]
  • CELL DEATH DIFFER. [4]
  • J CELL BIOL [4]
  • NAT CATAL [4]
  • PROTEIN SCI [4]
  • RNA [4]
  • ACS CENT SCI [3]
  • CELL HOST MICROBE [3]
  • INT J BIOL MACROMOL [3]
  • NAT CHEM [3]
  • NAT METHODS [3]
  • PNAS NEXUS [3]
  • VIRUSES [3]
  • ACS INFECT DIS. [2]
  • BIOCHEM J [2]
  • CELL CHEM BIOL [2]
  • CELL REP PHYS SCI [2]
  • FRONT MICROBIOL [2]
  • IUCRJ [2]
  • J MOL CELL BIOL [2]
  • J.BIOCHEM. [2]
  • PHILOS.TRANS.R.SOC.LOND.B BIOL.SCI. [2]
  • ACS CENTRAL SCIENCE [1]
  • ACS MED.CHEM.LETT. [1]
  • BBA ADV [1]
  • BIOMOLECULES [1]
  • CANCER DISCOV [1]
  • COMMUNICATIONS BIOLOGY [1]
  • CURR BIOL [1]
  • DEV CELL [1]
  • EBIOMEDICINE [1]
  • EUR.J.MED.CHEM. [1]
  • INNOVATION (NY) [1]
  • J CELL SCI [1]
  • J STRUCT BIOL [1]
  • J STRUCT BIOL X [1]
  • METHODS [1]
  • NAT CELL BIOL [1]
  • PLOS BIOL [1]
  • PLOS ONE [1]
  • PROTEINS [1]
  • SOIL BIOL.BIOCHEM. [1]
  • VACCINES (BASEL) [1]
  • VITA [1]

Software

  • CRYOSPARC [1096]
  • RELION [979]
  • CTFFIND [168]
  • GCTF [127]
  • FREALIGN [62]
  • CISTEM [56]
  • COOT [39]
  • UCSF CHIMERA [22]
  • CHIMERA [20]
  • DYNAMO [20]
  • WARP [18]
  • SPIDER [17]
  • PHENIX [16]
  • UCSF CHIMERAX [16]
  • EMCLARITY [11]
  • IMOD [9]
  • XMIPP [9]
  • CRYOLO [8]
  • CTFPHASEFLIP [6]
  • EMAN2, SPARX [5]
  • EMREADY [5]
  • ISOLDE [5]
  • MOTIONCORR2 [5]
  • SPIDER XMIPP [5]
  • EMAN [4]
  • EMAN2 [4]
  • IMAGIC [4]
  • SPARX [4]
  • EMAN, XMIPP [3]
  • IMAGIC, CTFIT, CTFFIND3 [3]
  • PEET [3]
  • RELION, CTFFIND3, EMAN2 [3]
  • RELION1.3 [3]
  • RELION_1.4 [3]
  • SERIALEM [3]
  • XMIPP, IMAGIC, SPIDER, APPION, CTFFIND3 [3]
  • BSOFT [2]
  • EMAN2, RELION [2]
  • IMAGIC-5 [2]
  • IMIRS [2]
  • RELION1.4 [2]
  • RELION_1.3 [2]
  • ADPEM [1]
  • CCP4 PACKAGE [1]
  • CHIMERA, VEDA [1]
  • CRYO [1]
  • CTFFIND3 [1]
  • EMAN, IMAGIC [1]
  • EMAN, SPIDER [1]
  • EMAN,IMAGIC [1]
  • EMIP, CHIMERA [1]
  • ETOMO [1]
  • GAUTOMATCH [1]
  • I3 [1]
  • IHRSR, XMIPP, IMAGIC, SPIDER, APPION, CTFFIND3 [1]
  • IMAGIC, RICO, BSOFT, CTFFIND3, FPM [1]
  • IMAGIC, SPIDER [1]
  • MATLAB [1]
  • MATLAB, IMAGEV [1]
  • MDFF METHOD [1]
  • MODELLER, CHIMERA, PHENIX, COOT [1]
  • MRC, EMIP, CHIMERA [1]
  • O [1]
  • SPDER [1]
  • SPIDER, EMAN [1]
  • SPIDER, RELION [1]
  • SPRING [1]
  • URO [1]
  • VEDA [1]
  • XMIPP AND EMAN [1]
  • XMIPP, EMAN2, SPIDER [1]

Microscope

  • FEI TITAN KRIOS [1894]
  • TFS KRIOS [1033]
  • FEI TALOS ARCTICA [136]
  • TFS GLACIOS [106]
  • FEI POLARA 300 [39]
  • FEI TECNAI F20 [25]
  • FEI TECNAI ARCTICA [23]
  • FEI TITAN [17]
  • FEI TECNAI F30 [16]
  • FEI TECNAI 20 [15]
  • FEI TECNAI 12 [14]
  • TFS TALOS [14]
  • TFS TALOS F200C [12]
  • JEOL CRYO ARM 300 [8]
  • JEOL 2000EX [5]
  • JEOL 2200FS [5]
  • JEOL CRYO ARM 200 [4]
  • JEOL 1230 [3]
  • JEOL 2010F [3]
  • JEOL 2100 [3]
  • JEOL 3200FS [3]
  • FEI TECNAI SPIRIT [2]
  • FEI/PHILIPS CM200FEG [2]
  • JEOL 1010 [2]
  • JEOL 1200EX [2]
  • JEOL 1200EXII [2]
  • JEOL 1400/HR YPS FEG [2]
  • FEI MORGAGNI [1]
  • FEI/PHILIPS CM300FEG/T [1]
  • JEOL 2100F [1]
  • JEOL 3200FSC [1]

Electron Source

  • FIELD EMISSION GUN [3333]
  • LAB6 [33]
  • TUNGSTEN HAIRPIN [19]
  • OTHER [8]

Film or detector model

  • GATAN K3 6K X 4K [1029]
  • GATAN K3 BIOQUANTUM 6K X 4K [754]
  • GATAN K2 SUMMIT 4K X 4K [716]
  • FEI FALCON IV 4K X 4K [259]
  • FEI FALCON III 4K X 4K [205]
  • GATAN K2 QUANTUM 4K X 4K [123]
  • TFS FALCON 4I 4K X 4K [100]
  • FEI FALCON II 4K X 4K [73]
  • GATAN K3 BIOCONTINUUM 6K X 4K [34]
  • KODAK SO-163 FILM [25]
  • GATAN ULTRASCAN 4000 4K X 4K [21]
  • TVIPS TEMCAM-F416 4K X 4K [12]
  • FEI CETA 4K X 4K [9]
  • GATAN K2 BASE 4K X 4K [6]
  • GENERIC GATAN [6]
  • GENERIC CCD [4]
  • GATAN K2 4K X 4K [3]
  • OTHER [3]
  • DECTRIS SINGLA 1K X 1K [2]
  • DIRECT ELECTRON DE-16 4K X 4K [2]
  • FEI EAGLE 4K X 4K [2]
  • GENERIC TVIPS 4K X 4K [2]
  • TVIPS TEMCAM-F415 4K X 4K [2]
  • DIRECT ELECTRON DE-64 8K X 8K [1]
  • FEI FALCON I 4K X 4K [1]
  • GATAN K2 IS 4K X 4K [1]
  • GATAN ULTRASCAN 1000 2K X 2K [1]
  • GENERIC GATAN 4K X 4K [1]
  • GENERIC TVIPS [1]

EMPIAR Experiment type

  • EMDB [32]
  • CLEM [6]
  • SXT [2]

EMPIAR Image category

  • MICROGRAPHS - MULTIFRAME [31]
  • MICROGRAPHS - SINGLE FRAME [12]
  • RECONSTRUCTED VOLUMES [3]
  • TILT SERIES [3]
  • PICKED PARTICLES - SINGLE FRAME - PROCESSED [2]

External links

  • UniProt [2882]
  • PDB [2842]
  • PDBe-Kb [2732]
  • Gene Ontology [2675]
  • InterPro [2576]
  • AlphaFold DB [2491]
  • Pfam [2442]
  • ChEBI [2013]
  • DrugBank [1975]
  • ChEMBL [1881]
  • Complex Portal [1486]
  • EMPIAR [407]
  • SCOP2 [42]
  • CATH [33]
  • EMDB [32]
  • BioImage Archive [6]